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Dive into the research topics where Matias Brødsgaard Grynderup is active.

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Featured researches published by Matias Brødsgaard Grynderup.


American Journal of Epidemiology | 2011

Job Strain and the Risk of Depression: Is Reporting Biased?

Henrik Kolstad; Åse Marie Hansen; Anette Kærgaard; Jane Frølund Thomsen; Linda Kaerlev; Sigurd Mikkelsen; Matias Brødsgaard Grynderup; Ole Mors; Reiner Rugulies; Ann Suhl Kristensen; Johan Myhre Andersen; Jens Peter Bonde

It is unknown whether the relation between job strain and depression reflects causal characteristics of the working environment or reporting bias. The authors investigated reporting bias by analyzing individual versus work-unit measures of job strain and the risk of depressive symptoms (n = 287) and a diagnosis of depression (n = 97) among 4,291 employees within 378 work units in Aarhus, Denmark, 2007. All participants reported psychological demands and decision latitude, and the authors estimated mean values for each work unit. The odds ratios predicting depressive symptoms or a diagnosis of depression for the highest versus the lowest levels of individual, self-reported high psychological demands and low decision latitude were significantly increased above 2.5. When participants were classified by the work-unit mean levels, these associations were substantially smaller. For depressive symptoms, the odds ratios were 1.49 (95% confidence interval (CI): 0.88, 2.53) and 1.08 (95% CI: 0.84, 1.39), respectively, for psychological demands and decision latitude. For a diagnosis of depression, the odds ratios were 1.33 (95% CI: 0.57, 3.09) and 1.02 (95% CI: 0.68, 1.56), respectively, for psychological demands and decision latitude. These findings indicate that reporting bias inflates associations between job strain and the occurrence of depression, if studies rely on individual self-reports.


Journal of Occupational and Environmental Medicine | 2014

Exposure to Workplace Bullying and Risk of Depression

Maria Gullander; Annie Hogh; Åse Marie Hansen; Roger Persson; Reiner Rugulies; Henrik Kolstad; Jane Frølund Thomsen; Morten Veis Willert; Matias Brødsgaard Grynderup; Ole Mors; Jens Peter Bonde

Objective: We examined the prospective association between self-labeled and witness-reported bullying and the risk of newly onset of depression. Methods: Employees were recruited from two cohorts of 3196 and 2002 employees, respectively. Participants received a questionnaire at baseline in 2006 to 2007 with follow-up in 2008 to 2009 and 2011. New cases of depression were diagnosed in the follow-up using Schedules for Clinical Assessment in Neuropsychiatry interviews and the Major Depression Inventory questionnaire. Results: We identified 147 new cases of depression. The odds ratio for newly onset depression among participants reporting bullying occasionally was 2.17 (95% confidence interval [CI]: 1.11 to 4.23) and among frequently bullied 9.63 (95% CI: 3.42 to 27.1). There was no association between percentage witnessing bullying and newly onset depression. Conclusions: Frequent self-labeled bullying predicts development of depression but a work environment with high proportion of employees witnessing bullying does not.


Scandinavian Journal of Work, Environment & Health | 2012

A two-year follow-up study of risk of depression according to work-unit measures of psychological demands and decision latitude

Matias Brødsgaard Grynderup; Ole Mors; Åse Marie Hansen; Johan Hviid Andersen; Jens Peter Bonde; Anette Kærgaard; Linda Kaerlev; Sigurd Mikkelsen; Reiner Rugulies; Jane Frølund Thomsen; Henrik Kolstad

OBJECTIVES The aim of this study was to examine if high psychological demands and low decision latitude at work increase the risk of depression. METHODS In 2007, 4237 non-depressed Danish public employees within 378 different work units were enrolled in the study. Mean levels of psychological demands and decision latitude were computed for each work unit to obtain exposure measures that were robust to reporting bias. In 2009, 3046 (72%) participated at follow-up, and those reporting high levels of depressive, burnout or stress symptoms went through a psychiatric interview by which 58 cases of new onset depression were diagnosed. Odds ratios (OR) of depression for different levels of work unit mean psychological demands and decision latitude were estimated by logistic regression taking established risk factors into account. RESULTS The OR for depression according to psychological demands was 1.07 [95% confidence interval (95% CI) 0.42-2.49] for every unit of change on a 5-point scale. The corresponding OR for decision latitude was 1.85 (95% CI 0.55-6.26). No interactive effects of psychological demands and decision latitude were observed. CONCLUSION These findings suggest that low decision latitude may predict depression, but confidence intervals are wide and findings are also compatible with no increased risk.


Journal of Occupational and Environmental Medicine | 2016

Negative Acts at Work as Potential Bullying Behavior and Depression: Examining the Direction of the Association in a 2-Year Follow-Up Study.

Annie Hogh; Paul Maurice Conway; Matias Brødsgaard Grynderup; Maria Gullander; Morten Veis Willert; Eva Gemzøe Mikkelsen; Roger Persson; Jens Peter Bonde; Henrik Kolstad; Ole Mors; Reiner Rugulies; Linda Kaerlev; Åse Marie Hansen

Objective: This study investigates the 2-year prospective association between exposure to negative acts at work and depression. Methods: A questionnaire study was carried out among 3363 employees and followed up 2 years later. Negative acts as potential bullying behavior were assessed by the Revised Negative Acts Questionnaire and depression by The Major Depression Inventory or Schedule for Clinical Assessment in Neuropsychiatry interviews. Logistic regression analyses tested potential associations between depression and negative acts. Results: Exposure to negative acts was associated with depression 2 years later; however, when adjusting for Sense of Coherence and depressive symptoms at baseline the association was no longer significant. Conversely, depression at baseline predicted self-reported exposure to negative acts at follow-up. Conclusions: Depression predicts exposure to negative acts at a 2-year follow-up, whereas negative acts do not predict depression after adjustment for Sense of Coherence and baseline depressive symptoms.


Journal of Psychosomatic Research | 2015

Are changes in workplace bullying status related to changes in salivary cortisol? A longitudinal study among Danish employees

Maria Gullander; Matias Brødsgaard Grynderup; Åse Marie Hansen; Annie Hogh; Roger Persson; Henrik Kolstad; Ole Mors; Linda Kaerlev; Jens Peter Bonde

OBJECTIVES This study aims to investigate whether incident workplace bullying and its dicontinuance is related to subsequent change in morning and evening saliva cortisol concentrations. METHODS Participants came from two Danish cohort studies, the PRISME cohort (n=4489) and the Workplace Bullying and Harassment Cohort (n=3707). At baseline and follow-up exposure to bullying was measured by a single question on bullying (preceded by a definition). Two saliva samples to measure cortisol were collected during a work-day (30 min after awakening and at 8 p.m.). All participants responding to the item on workplace bullying, giving saliva samples and participated at both baseline and follow-up were included. The reference group consisted of non-bullied respondents at both baseline and follow-up. Multilevel mixed-effects linear regressions were used to test for changes in salivary cortisol after newly onset of and discontinuance of workplace bullying. All analyses were adjusted for the potentially confounding effect of differences from baseline to follow-up in education, smoking, alcohol consumption, body mass index, cohort, sampling waves, time of awakening, and time of sampling. RESULTS We found no indication of statistically significant difference in saliva cortisol, neither when participants changed their self-labelling from not bullied at baseline to being bullied at follow-up, nor when they at follow-up two years later reported discontinuance of bullying. CONCLUSION This longitudinal study on the impact of changes in bullying status on change in cortisol levels showed consistent lack of associations with onset and discontinuance of workplace bullying.


Scandinavian Journal of Work, Environment & Health | 2016

Workplace bullying, sleep problems and leisure-time physical activity: a prospective cohort study

Åse Marie Hansen; Maria Gullander; Annie Hogh; Roger Persson; Henrik Kolstad; Morten Vejs Willert; Jens Peter Bonde; Linda Kaerlev; Reiner Rugulies; Matias Brødsgaard Grynderup

OBJECTIVES Workplace bullying is a potent stressor that may increase sleep problems. Since physical fitness improves resilience to stress, it seems plausible that recreational physical activities may moderate the association between bullying and sleep. The study aimed to examine prospectively whether (i) bullying increases the risk of sleep problems, and (ii) the association between bullying and sleep problems is moderated by leisure-time physical activity (LTPA). METHODS The study sample comprised a cohort of public and private sector employees, who were enrolled into the Work Bullying and Harassment (WBH) cohort (N=3278) or the Psychosocial Risk Factors for Stress and Mental Disease (PRISME) cohort (N=4455). We measured workplace bullying using one question that was preceded by a definition of bullying. We used the Karolinska sleep questionnaire to assess sleep problems. The number of hours per week spent on LTPA estimated the degree of physical activity. RESULTS Workplace bullying at baseline (T1) was associated with awakening problems and lack of restful sleep at follow-up (T2) but not with overall sleep problems and disturbed sleep. T1-LTPA did not moderate the association between T1-workplace bullying and T2-sleep problems. CONCLUSION We found support that workplace bullying is related to development of T2-sleep problems, but this association seems not to be modified by LTPA.


Audiology and Neuro-otology | 2014

Atherogenic Risk Factors and Hearing Thresholds

Thomas Winther Frederiksen; Cecilia Høst Ramlau-Hansen; Zara Ann Stokholm; Matias Brødsgaard Grynderup; Åse Marie Hansen; Søren Peter Lund; Jesper Medom Vestergaard; Jesper Kristiansen; Jens Peter Bonde; Henrik Kolstad

The objective of this study was to evaluate the influence of atherogenic risk factors on hearing thresholds. In a cross-sectional study we analyzed data from a Danish survey in 2009-2010 on physical and psychological working conditions. The study included 576 white- and blue-collar workers from childrens day care units, financial services and 10 manufacturing trades. Associations between atherogenic risk factors (blood lipids, glycosylated hemoglobin, smoking habits, body mass index (BMI), and ambulatory blood pressure) and hearing thresholds were analyzed using multiple linear regression models. Adjusted results suggested associations between smoking, high BMI and triglyceride level and low high-density lipoprotein level and increased low-frequency hearing thresholds (average of pure-tone hearing thresholds at 0.25, 0.5 and 1 kHz). Furthermore, an increasing load of atherogenic risk factors seemed associated with increased low-frequency hearing thresholds, but only at a borderline level of statistical significance. Associations were generally strongest with hearing levels of the worst hearing ear. We found no statistically significant associations between atherogenic risk factors and high-frequency hearing thresholds (average of pure-tone hearing thresholds at 4, 6 and 8 kHz).


International Archives of Occupational and Environmental Health | 2017

Occupational noise exposure, psychosocial working conditions and the risk of tinnitus.

Thomas Winther Frederiksen; Cecilia Høst Ramlau-Hansen; Zara Ann Stokholm; Matias Brødsgaard Grynderup; Åse Marie Hansen; Søren Peter Lund; Jesper Kristiansen; Jesper Medom Vestergaard; Jens Peter Bonde; Henrik Kolstad

PurposeThe purpose of this study was to evaluate the influence of occupational noise (current and cumulative doses) and psychosocial work factors (psychological demands and decision latitude) on tinnitus occurrence among workers, using objective and non-self-reported exposure measures to prevent reporting bias.MethodsIn a cross-sectional study, we analyzed data from a Danish survey from 2009 to 2010 that included 534 workers from children day care units and 10 manufacturing trades. Associations between risk factors (current noise exposure, cumulative noise exposure and psychosocial working conditions) and tinnitus were analyzed with logistic regression.ResultsWe found no statistically significant associations between either current [OR 0.95 (95% CI 0.89; 1.01)] or cumulative [OR 0.93 (95% CI 0.81; 1.06)] occupational noise exposure and tinnitus. Likewise, results for psychosocial working conditions showed no statistically significant association between work place decision latitude [OR 1.06 (95% CI 0.94; 1.13)] or psychological demands [OR 1.07 (95% CI 0.90; 1.26)] and tinnitus.ConclusionsOur results suggest that current Danish occupational noise levels (in combination with relevant noise protection) are not associated with tinnitus. Also, results indicated that the psychosocial working conditions we observed in this cohort of mainly industrial workers were not associated with tinnitus. Therefore, psychosocial working conditions comparable to those observed in this study are probably not relevant to take into account in the evaluation of workers presenting with tinnitus.


Journal of Occupational and Environmental Medicine | 2016

Relationship Between Changes in Workplace Bullying Status and the Reporting of Personality Characteristics

Roger Persson; Annie Hogh; Matias Brødsgaard Grynderup; Morten Vejs Willert; Maria Gullander; Åse Marie Hansen; Henrik Kolstad; Ole Mors; Eva Gemzøe Mikkelsen; Ann Suhl Kristensen; Linda Kaerlev; Reiner Rugulies; Jens Peter Bonde

Objective: To examine whether a shift in work-related bullying status, from being non-bullied to being bullied or vice versa, was associated with changes in reporting of personality characteristics. Methods: Data on bullying and personality (neuroticism, extraversion, and sense of coherence) were collected in three waves approximately 2 years apart (N = 4947). Using a within-subjects design, personality change scores that followed altered bullying status were evaluated with one-sample t tests. Sensitivity analyses targeted depressive symptoms. Results: Shifts from non-bullied to frequently bullied were associated with increased neuroticism or decreased sense of coherence manageability scores. Shifts from bullied to non-bullied were associated with decreasing neuroticism and increasing extraversion scores, or increasing sense of coherence meaningfulness and comprehensibility scores. Excluding depressive cases had minor effects. Conclusions: Bullying seems to some extent to affect personality scale scores, which thus seem sensitive to environmental and social circumstances.


Journal of Occupational and Environmental Medicine | 2016

Emotional Demands at Work and the Risk of Clinical Depression: A Longitudinal Study in the Danish Public Sector

Marianne Agergaard Vammen; Sigurd Mikkelsen; Åse Marie Hansen; Jens Peter Bonde; Matias Brødsgaard Grynderup; Henrik Kolstad; Linda Kaerlev; Ole Mors; Reiner Rugulies; Jane Frølund Thomsen

Objective: This study is a 2-year follow-up study of different dimensions of work-related emotional demands as a predictor for clinical depression. Methods: In a two-wave study, 3224 (72%) public employees from 474 work-units participated twice by filling in questionnaires. Sixty-two cases of clinical depression were diagnosed. Emotional demands were examined as perceived and content-related emotional demands, individually reported and work-unit based. Support, meaningful work, and enrichment were considered as potential effect modifiers. Results: Individually reported perceived emotional demands predicted depression (odds ratio: 1.40; 95% confidence intervals: 1.02 to 1.92). The work-unit based odds ratio was in the same direction, though not significant. Content-related emotional demands did not predict depression. Support, meaningful work, and enrichment did not modify the results. Conclusions: The personal perception of emotional demands was a risk factor for clinical depression but specific emotionally demanding work tasks were not.

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Annie Hogh

University of Copenhagen

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Linda Kaerlev

University of Southern Denmark

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