Matija Milosevic

Visualization of Trunk Muscle Synergies During Sitting Perturbations Using Self-Organizing Maps (SOM)

The purpose of this study was to demonstrate the use of the self-organizing map (SOM) method for visualization, modeling, and comparison of trunk neuromuscular synergies during perturbed sitting. Thirteen participants were perturbed at the level of the sternum, in eight directions during sitting. Electromyographic (EMG) responses of ten trunk muscles involved in postural control were recorded. The SOM was used to encode the EMG responses on a 2-D projection (i.e., visualization). The result contains similar patterns mapped close together on the plot therefore forming clusters of data. Such visualization of ten EMG responses, following eight directional perturbations, allows for comparisons of direction-dependent postural synergies. Direction-dependent neuromuscular response models for each muscle were then constructed from the SOM visualization. The results demonstrated that the SOM was able to encode neuromuscular responses, and the SOM visualization showed direction-dependent differences in the postural synergies. Moreover, each muscle was modeled using the SOM-based method, and derived models showed that all muscles, except for one, produced a Gaussian fit for direction-dependent responses. Overall, SOM analysis offers a reverse engineering method for exploration and comparison of complex neuromuscular systems, which can describe postural synergies at a glance.

Trunk control impairment is responsible for postural instability during quiet sitting in individuals with cervical spinal cord injury.

BACKGROUND Individuals with cervical spinal cord injury usually sustain impairments to the trunk and upper and lower limbs, resulting in compromised sitting balance. The objectives of this study were to: 1) compare postural control of individuals with cervical spinal cord injury and able-bodied individuals; and 2) investigate the effects of foot support and trunk fluctuations on postural control during sitting balance. METHODS Ten able-bodied individuals and six individuals with cervical spinal cord injury were asked to sit quietly during two 60s trials. The forces exerted on the seat and the foot support surfaces were measured separately using two force plates. The global centre of pressure sway was obtained from the measurements on the two force plates, and the sway for each force plate was calculated individually. FINDINGS Individuals with spinal cord injury had at least twice as large global and seat sways compared to able-bodied individuals, while foot support sway was not significantly different between the two groups. Comparison between global and seat sways showed that anterior-posterior velocity of global sway was larger compared to the seat sway in both groups. INTERPRETATION Postural control of individuals with cervical spinal cord injury was worse than that of able-bodied individuals. The trunk swayed more in individuals with spinal cord injury, while the stabilization effect of the feet did not differ between the groups. Foot support affected anterior-posterior fluctuations in both groups equally. Thus, trunk control is the dominant mechanism contributing to sitting balance in both able-bodied and spinal cord injury individuals.

Anticipation of direction and time of perturbation modulates the onset latency of trunk muscle responses during sitting perturbations

Trunk muscles are responsible for maintaining trunk stability during sitting. However, the effects of anticipation of perturbation on trunk muscle responses are not well understood. The objectives of this study were to identify the responses of trunk muscles to sudden support surface translations and quantify the effects of anticipation of direction and time of perturbation on the trunk neuromuscular responses. Twelve able-bodied individuals participated in the study. Participants were seated on a kneeling chair and support surface translations were applied in the forward and backward directions with and without direction and time of perturbation cues. The trunk started moving on average approximately 40ms after the perturbation. During unanticipated perturbations, average latencies of the trunk muscle contractions were in the range between 103.4 and 117.4ms. When participants anticipated the perturbations, trunk muscle latencies were reduced by 16.8±10.0ms and the time it took the trunk to reach maximum velocity was also reduced, suggesting a biomechanical advantage caused by faster muscle responses. These results suggested that trunk muscles have medium latency responses and use reflexive mechanisms. Moreover, anticipation of perturbation decreased trunk muscles latencies, suggesting that the central nervous system modulated readiness of the trunk based on anticipatory information.

Evaluation of Protective Gloves and Working Techniques for Reducing Hand-arm Vibration Exposure in the Workplace

Evaluation of Protective Gloves and Working Techniques for Reducing Hand‐arm Vibration Exposure in the Workplace: Matija MILOSEVIC, et al. Electrical and Computer Engineering Department, Ryerson University, Canada—

Trunk muscle co-activation using functional electrical stimulation modifies center of pressure fluctuations during quiet sitting by increasing trunk stiffness.

BackgroundThe purpose of this study was to examine the impact of functional electrical stimulation (FES) induced co-activation of trunk muscles during quiet sitting. We hypothesized that FES applied to the trunk muscles will increase trunk stiffness. The objectives of this study were to: 1) compare the center of pressure (COP) fluctuations during unsupported and FES-assisted quiet sitting - an experimental study and; 2) investigate how FES influences sitting balance - an analytical (simulation) study.MethodsThe experimental study involved 15 able-bodied individuals who were seated on an instrumented chair. During the experiment, COP of the body projected on the seating surface was calculated to compare sitting stability of participants during unsupported and FES-assisted quiet sitting. The analytical (simulation) study examined dynamics of quiet sitting using an inverted pendulum model, representing the body, and a proportional-derivative (PD) controller, representing the central nervous system control. This model was used to analyze the relationship between increased trunk stiffness and COP fluctuations.ResultsIn the experimental study, the COP fluctuations showed that: i) the mean velocity, mean frequency and the power frequency were higher during FES-assisted sitting; ii) the frequency dispersion for anterior-posterior fluctuations was smaller during FES-assisted sitting; and iii) the mean distance, range and centroidal frequency did not change during FES-assisted sitting. The analytical (simulation) study showed that increased mechanical stiffness of the trunk had the same effect on COP fluctuations as the FES.ConclusionsThe results of this study suggest that FES applied to the key trunk muscles increases the speed of the COP fluctuations by increasing the trunk stiffness during quiet sitting.

Arm movement effect on balance

The background research shows a high incidence of falls and loss of balance related injuries, which cause serious consequences to individual health and quality of life, as well as substantial healthcare impact in services and costs. The literature review emphasizes that arm movements have a potentially significant effect on balance, and indentifies the use of balance boards as a relevant and meaningful tool for dynamic balance evaluation. The primary objective of this initial study was to develop a method to test and evaluate the effect of arm movements on the maintenance of postural stability. Further we investigated the impact of dominant and non-dominant arms, the reaction time of arms, and the amount of activity of arms related to dynamic balance control. The study applied an accelerometer-based balance board test to measure postural stability as related to arm movements. The evaluation consists of accelerometers placed on the two arms and the balance board. Data were acquired from four different subjects and processed accordingly. The finding verified that arms play an important role in the improvement of balance. Our findings suggest that the dominant arm is more active in balance control and that the movement of arms most often occurs just prior to and during loss of balance. The results also suggest that the amount of arm movement activity directly relates to balance control and the use of the dominant arm.

Head Movement Effects in a Cost-Effective Virtual Reality Training Environment for Balance Rehabilitation

Falling is a major risk to the health and quality of life for the elderly and for those with vestibular impairment. Virtual environments have been investigated in the past for their potential for vestibular rehabilitation. In this study, a low cost, off-the-shelf virtual reality game was evaluated for user head movements. Two levels of difficulty were used in the training, conducted in five sessions over the course of one week. Subjects felt very immersed in the environment and game performance increased gradually. Lateral head movements were recorded consistently throughout the training period and between difficulty levels, with a range of 60° left and right. Performance on standard balance tests after training also showed improvement. This suggests that this readily available virtual reality game could be used in balance rehabilitation.

Lateral hypothalamic activity indicates hunger and satiety states in humans

Lateral hypothalamic area (LHA) local field potentials (LFPs) were recorded in a Prader–Willi patient undergoing deep brain stimulation (DBS) for obesity. During hunger, exposure to food‐related cues induced an increase in beta/low‐gamma activity. In contrast, recordings during satiety were marked by prominent alpha rhythms. Based on these findings, we have delivered alpha‐frequency DBS prior to and during food intake. Despite reporting an early sensation of fullness, the patient continued to crave food. This suggests that the pattern of activity in LHA may indicate hunger/satiety states in humans but attest to the complexity of conducting neuromodulation studies in obesity.

Relationship Between Posturography, Clinical Balance and Executive Function in Parkinson´s Disease

ABSTRACT This study aimed to evaluate the relationship between posturography, clinical balance, and executive function tests in Parkinson´s disease (PD). Seventy-one people participated in the study. Static posturography evaluated the center of pressure fluctuations in quiet standing and dynamic posturography assessed sit-to-stand, tandem walk, and step over an obstacle. Functional balance was evaluated by Berg Balance Scale, MiniBESTest, and Timed Up and Go test. Executive function was assessed by Trail Making Test (TMT) and semantic verbal fluency test. Step over obstacle measures (percentage of body weight transfer and movement time) were moderately correlated to Timed Up and Go, part B of TMT and semantic verbal fluency (r > 0.40; p < 0.05 in all relationships). Stepping over an obstacle assesses the responses to internal perturbations. Participants with shorter movement times and higher percentage of body weight transfer (higher lift up index) on this task were also faster in Timed Up and Go, part B of TMT, and semantic verbal fluency. All these tasks require executive function (problem solving, sequencing, shifting attention), which is affected by PD and contribute to postural assessment.