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Dive into the research topics where Matthew J. Dougherty is active.

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Featured researches published by Matthew J. Dougherty.


Surgery | 1995

Venous aneurysms : surgical indications and review of the literature

Keith D. Calligaro; Syed Ahmad; Rahul Dandora; Matthew J. Dougherty; Ronald P. Savarese; Kevin J. Doerr; Sandy McAffee; Dominic A. DeLaurentis

BACKGROUND During the last 20 years we diagnosed five cases of venous aneurysm of the jugular (n = 4) and basilic (n = 1) veins. The purpose of this report was to determine the natural history and indications for surgery of venous aneurysms. METHODS Our five cases were included in an English-language literature review performed through August 1993. RESULTS In our series two aneurysms (one external jugular vein, one basilic vein) were excised for cosmetic reasons. Three internal jugular vein aneurysms were followed up for up to 4 years without complications with serial color duplex ultrasonography. Of 32 patients with abdominal venous aneurysms (18 portal, seven inferior vena cava, four superior mesenteric, two splenic, one internal iliac), 13 (41%) had major complications including five deaths. Of 31 patients with deep venous aneurysms of the extremity (29 popliteal, two common femoral), 22 (71%) had deep vein thrombosis or pulmonary embolism and in 17 recurrent deep vein thrombosis or pulmonary embolism developed when patients were treated with anticoagulation alone. CONCLUSIONS Prophylactic surgery is cautiously recommended for low-risk patients with venous aneurysms of the abdomen and strongly recommended for most patients with lower extremity deep venous aneurysms. Other venous aneurysms should be excised only if they are symptomatic, enlarging, or disfiguring.


Journal of Vascular Surgery | 2003

Acute arterial complications associated with total hip and knee arthroplasty

Keith D. Calligaro; Matthew J. Dougherty; Sean V Ryan; Robert E. Booth

OBJECTIVE To our knowledge, ours is the largest single-center experience with diagnosis and management of acute arterial hemorrhagic and limb-threatening ischemic complications associated with total hip arthroplasty (THA) and total knee arthroplasty (TKA). METHODS Between 1989 and 2002, 23,199 TKA procedures (13,618 total, 11,953 primary, 1665 revision) and THR procedures (9581 total, 7812 primary, 1769 revision) were performed at the orthopedic service of Pennsylvania Hospital, Philadelphia. Arterial injuries were grouped according to type (ischemia, bleeding, pseudoaneurysm, ischemia plus bleeding) and time of recognition of injury (0-5 days after orthoplasty). RESULTS Acute arterial complications developed in 32 patients (0.13%), associated with 24 TKA procedures (0.17%) and 8 THA procedures (0.08%; P =.0609). There were no deaths, and limb salvage was achieved in all patients. Arterial injury was detected by the orthopedic service on the same day (SD group) as performance of joint replacement in 18 patients (56%), but was not recognized until the first to fifth postoperative day (PO group) in 14 patients (44%). Arterial complications included acute lower-limb ischemia only in 18 patients SD group, 9; PO group, 9), bleeding only in 4 patients (SD group), arterial transection resulting in both ischemia and bleeding in 5 patients (SD group), and arterial pseudoaneurysm in 5 patients (PO group). Of the 18 patients with acute ischemia only, preoperative arteriography was performed in 12 patients (67%), and 6 patients (33%) were brought directly to the operating room because of advanced ischemia. Revascularization procedures in these 18 patients included bypass to the infrapopliteal artery (n = 7), popliteal artery (n = 5), or common femoral artery (n = 1); in only 5 patients (28%) was thrombectomy alone successful. These 18 patients tended to require fasciotomy (4 of 9 vs 2 of 9; P =.6199) and have foot drop (3 of 9 vs 1 of 9; P =.5765) more frequently when ischemia was recognized after the day of surgery. Bleeding was managed with arteriorrhaphy. Arterial transection was treated with end-to-end anastomosis (n = 3), interposition grafting (n = 1), and below-knee popliteal bypass (n = 1). Popliteal artery pseudoaneurysm was treated with percutaneous methods (n = 3) or surgery (n = 2). CONCLUSION In this series, risk for arterial injury associated with THA and TKA was remarkably low. Nonetheless, even at a high-volume orthopedic hospital, acute arterial injury was not recognized on the day of surgery in about half of patients. Judicious use of preoperative arteriography and aggressive revascularization are critical to achieving limb salvage. Simple arterial thrombectomy to treat ischemic complications of THA and TKA is rarely sufficient.


Journal of Vascular Surgery | 1995

Impact of clinical pathways on hospital costs and early outcome after major vascular surgery

Keith D. Calligaro; Matthew J. Dougherty; Carol A. Raviola; David J. Musser; Dominic A. DeLaurentis

PURPOSE The purpose of this study was to determine whether major vascular surgery could be performed safely and with significant hospital cost savings by decreasing length of stay and implementation of vascular clinical pathways. METHODS Morbidity, mortality, readmission rates, same-day admissions, length of stay, and hospital costs were compared between patients who were electively admitted between September 1, 1992, and August 30, 1993 (group 1), and January 1 to December 31, 1994 (group 2), for extracranial, infrarenal abdominal aortic, and lower extremity arterial surgery. For group 2 patients, vascular critical pathways were instituted, a dedicated vascular ward was established, and outpatient preoperative arteriography and anesthesiology-cardiology evaluations were performed. Length-of-stay goals were 1 day for extracranial, 5 days for aortic, and 2 to 5 days for lower extremity surgery. Emergency admissions, inpatients referred for vascular surgery, patients transferred from other hospitals, and patients who required prolonged preoperative treatment were excluded. RESULTS With this strategy same-day admissions were significantly increased (80% [145/177] vs 6.2% [9/145]) (p < 0.0001), and average length of stay was significantly decreased (3.8 vs 8.8 days) (p < 0.0001) in group 2 versus group 1, respectively. There were no significant differences between group 1 and group 2 in terms of overall mortality rate (2.1% [3/145] vs 2.3% [4/177]), cardiac (3.4% [5/145] vs 4.0% [7/177]), pulmonary (4.1% [6/145] vs 1.7% [3/177]), or neurologic (1.4% [2/145] vs 0% [0/177]) complications, or readmission within 30 days (11.3% [16/142] vs 9.2% [16/173]) (p > 0.05). There were also no differences in morbidity or mortality rates when each type of surgery was compared. Annual hospital cost savings totalled


Journal of Vascular Surgery | 1996

Congenitally absent inferior vena cava presenting in adulthood with venous stasis and ulceration: A surgically treated case

Matthew J. Dougherty; Keith D. Calligaro; Dominic A. DeLaurentis

1,267,445. CONCLUSION Same-day admission and early hospital discharge for patients undergoing elective major vascular surgery can result in significant hospital cost savings without apparent increase in morbidity or mortality rates.


Journal of Vascular Surgery | 2009

Duplex ultrasound imaging alone is sufficient for midterm endovascular aneurysm repair surveillance: A cost analysis study and prospective comparison with computed tomography scan

Brian R. Beeman; Lynne M. Doctor; Kevin Doerr; Sandy McAfee-Bennett; Matthew J. Dougherty; Keith D. Calligaro

Absence of the inferior vena cava (IVC) is an uncommon congenital abnormality. Symptoms of lower extremity venous insufficiency resulting from this anatomic abnormality have been reported only once in the English literature, and no experience with surgical treatment of this condition has been published. We report the case of an otherwise healthy 41-year-old man with an 18-month history of severe venous insufficiency involving the right leg manifested by extensive ulceration that did not respond to aggressive conservative treatment. Duplex findings were not suggestive of venous obstruction or reflux, but venography documented no filling of the common iliac vein or inferior vena cava, and outflow was via collaterals to the azygous and hemiazygous systems. Computed tomography demonstrated complete absence of the inferior vena cava with azygous continuation. A prosthetic bypass from the external iliac to the intrathoracic azygous vein was performed with complete symptomatic relief after a 30-month follow-up period. Venous bypass surgery may play a role in treatment of this rare cause of venous insufficiency.


Journal of Vascular Surgery | 1999

Endovascular versus surgical treatment for thrombosed hemodialysis grafts: A prospective, randomized study

Matthew J. Dougherty; Keith D. Calligaro; Nancy Schindler; Carol A. Raviola; Adu Ntoso

OBJECTIVE Early in our experience with endovascular aortic aneurysm repair (EVAR) we performed both serial computed tomography scans and duplex ultrasound (DU) imaging in our post-EVAR surveillance regimen. Later we conducted a prospective study with DU imaging as the sole surveillance study and determined cost savings and outcome using this strategy. METHODS From September 21, 1998, to May 30, 2008, 250 patients underwent EVAR at our hospital. Before July 1, 2004, EVAR patients underwent CT and DU imaging performed every 6 months during the first year and then annually if no problems were identified (group 1). We compared aneurysm sac size, presence of endoleak, and graft patency between the two scanning modalities. After July 1, 2004, patients underwent surveillance using DU imaging as the sole surveillance study unless a problem was detected (group 2). CT and DU imaging charges for each regimen were compared using our 2008 health system pricing and Medicare reimbursements. All DU examinations were performed in our accredited noninvasive vascular laboratory by experienced technologists. Statistical analysis was performed using Pearson correlation coefficient. RESULTS DU and CT scans were equivalent in determining aneurysm sac diameter after EVAR (P < .001). DU and CT were each as likely to falsely suggest an endoleak when none existed and were as likely to miss an endoleak. Using DU imaging alone would have reduced cost of EVAR surveillance by 29% (


Journal of Vascular Surgery | 2003

Intra-abdominal aortic graft infection: complete or partial graft preservation in patients at very high risk

Keith D. Calligaro; Frank J. Veith; John G. Yuan; Nicholas J. Gargiulo; Matthew J. Dougherty

534,356) in group 1. Cost savings of


Annals of Surgery | 1994

Selective preservation of infected prosthetic arterial grafts. Analysis of a 20-year experience with 120 extracavitary-infected grafts.

Keith D. Calligaro; Frank J. Veith; Michael L. Schwartz; Jamie Goldsmith; Ronald P. Savarese; Matthew J. Dougherty; Dominic A. DeLaurentis

1595 per patient per year were realized in group 2 by eliminating CT scan surveillance. None of the group 2 patients sustained an adverse event such as rupture, graft migration, or limb occlusion as a result of having DU imaging performed as the sole follow-up modality. CONCLUSION Surveillance of EVAR patients can be performed accurately, safely, and cost-effectively with DU as the sole imaging study.


Journal of Vascular Surgery | 1994

Acute arterial thrombosis associated with total knee arthroplasty

Keith D. Calligaro; Dominic A. DeLaurentis; Robert E. Booth; Richard H. Rothman; Ronald P. Savarese; Matthew J. Dougherty

PURPOSE The objective of this study was to compare clinical outcome and costs for two widely used treatment strategies for hemodialysis graft thrombosis. METHODS During a 4-year period, 80 patients with thrombosed dialysis grafts were randomly assigned to surgical thrombectomy with or without graft revision (SURG) or thrombolytic therapy with urokinase with the pulse-spray technique (ENDO), with adjunctive percutaneous transluminal angioplasty as indicated. All the procedures were performed in an endovascular operating suite with fistulography. The clinical and cost data were tabulated, and the outcome was analyzed with the life-table method. RESULTS Fifty-six women and 24 men ranged in age from 33 to 90 years (mean, 63.7 years). The patients had undergone a mean of 2.8 prior access procedures in the ipsilateral extremity. All the grafts were upper extremity expanded polytetrafluoroethylene grafts. Lesions that were presumed to be the primary cause of graft thrombosis were identified in 73 of 80 grafts, and 60 of these were at the venous anastomosis. The procedure time averaged 99 minutes for the patients in the SURG group and 113 minutes for the patients in the ENDO group (P =.12). Eleven patients in the ENDO group crossed over to surgical revision as compared with two patients in the SURG group who required adjunctive percutaneous transluminal angioplasty (P =.005). The mean cost of treatment (including room and supply costs but not professional fees) was significantly higher for the ENDO group than for the SURG group (


Journal of Vascular Surgery | 1997

Use of arm and lesser saphenous vein compared with prosthetic grafts for infrapopliteal arterial bypass: Are they worth the effort?

Keith D. Calligaro; Jennifer R. Syrek; Matthew J. Dougherty; Ignacio Rua; Carol A. Raviola; Dominic A. DeLaurentis

2945 vs

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Kevin J. Doerr

University of Pennsylvania

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Sam Tyagi

Pennsylvania Hospital

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