Matthew T. Keough

Context counts: Solitary drinking explains the association between depressive symptoms and alcohol-related problems in undergraduates

INTRODUCTION According to theory, depressed individuals self-medicate their negative affect with alcohol. Due to isolation and interpersonal difficulties, undergraduates with elevated depressive symptoms may do much of their drinking alone and/or in intimate contexts (e.g., with family or romantic partners) rather than at normative social events (e.g., parties). Evidence suggests drinking in these contexts leads to heavy use and alcohol-related problems. Accordingly, context may be an explanatory mechanism linking depressive symptoms to problematic drinking. This pathway remains understudied in the literature. Our study aimed to examine solitary and intimate drinking as distinct mediators of the depression-problematic drinking association. We hypothesized that depressive symptoms would be positively associated with solitary and intimate drinking which in turn would be associated with elevated alcohol use and related problems. METHODS Undergraduates (N=295; 72% women) completed online self-reports. RESULTS Consistent with hypotheses, path analyses supported depressive symptoms as a positive predictor of solitary drinking, which in turn was a positive predictor of alcohol-related problems, but not of alcohol use. Counter to hypotheses, depressive symptoms were unrelated to intimate drinking. Interestingly, depressive symptoms were negatively associated with drinking at parties, which in turn led to reduced risk for elevated alcohol use and related problems. CONCLUSIONS Our results shed new light on the depression pathway to problematic drinking in undergraduates by considering the role of drinking context. Our findings suggest undergraduates with elevated depressive symptoms are at risk for potentially problematic drinking because they are drinking alone. Solitary drinking represents a malleable target for clinical interventions aimed at reducing risky depression-related alcohol use.

Clarifying the measurement and the role of the behavioral inhibition system in alcohol misuse

BACKGROUND In response to conflicting reward (Behavioral Approach System [BAS]) and/or punishment cues (Fight-Flight-Freeze System [FFFS]) the Behavioral Inhibition System (BIS) inhibits behavior, leading to increased attention to threat, high anxiety, and behavioral ambivalence. The role of BIS in alcohol misuse is complex, as anxiety promotes self-medication drinking, while attention to threat (e.g., negative outcomes of heavy drinking) may reduce risk. Theory suggests that a concurrent strong BAS may bias BIS-conflict in favor of alcohol approach, while a concurrent strong FFFS may increase the likelihood of alcohol avoidance. However, few studies measure BIS as a conflict system, and no studies incorporate such a measure into examinations of alcohol misuse. Our study goals were to (i) test the Motivational Flanker Task (MFT) as a new laboratory measure of the BIS, BAS, and FFFS; and (ii) use the MFT, in conjunction with self-report measures, to test BAS and FFFS as moderators of the BIS-alcohol misuse relation. We hypothesized that an elevated BIS would predict heavy drinking and alcohol-related problems, but only when BAS was high. Further, we expected an elevated BIS to be associated with reduced alcohol misuse, but only when FFFS was high. METHODS Students (N = 198) completed self-reports of BIS/BAS/FFFS and drinking behavior, and 2 reaction time tasks: MFT and Point Scoring Reaction Time Task (PSRTT). The PSRTT is a published measure of the revised BIS. RESULTS MFT BIS conflict was associated with self-report and PSRTT measures. MFT BAS, but not FFFS, was associated with self-reports. As expected, elevated BIS was associated with heavy drinking, but only when BAS-Drive and BAS-Fun Seeking was also high. FFFS was not supported as a moderator of the BIS-alcohol misuse association. CONCLUSIONS Results support the MFT as a promising measure of the revised BIS. Considering the joint effects of BIS and BAS clarified risk for alcohol misuse.

Getting the party started — Alone: Solitary predrinking mediates the effect of social anxiety on alcohol-related problems ☆

Predrinking (or pregaming) is common among undergraduates and has been linked with problem alcohol use. While many students predrink to save money, evidence suggests that some students predrink to cope with social anxiety (SA). Tension reduction and cognitive theories predict that those high in SA may predrink to reduce anticipatory anxiety before attending social events and their predrinking may be done alone rather than in normative social contexts. Available data suggest that, relative to social drinking, solitary drinking elevates risk for alcohol use and related problems. Informed by this evidence, we speculated that context for predrinking may be an important mechanism by which SA-risk for alcohol use unfolds. Specifically, we offered the novel hypothesis that those high in SA would engage frequently in solitary predrinking and this in turn would be associated with elevated alcohol use and related problems. Undergraduate drinkers (N=293; 70% women) completed self-reports of social anxiety, predrinking context (social, solitary), alcohol use, and alcohol-related problems. In partial support of our hypotheses, SA was a positive predictor of solitary predrinking, which in turn predicted elevated alcohol-related problems, but not alcohol use. While not hypothesized, we also found that SA was a negative predictor of social predrinking, which in turn reduced risk for alcohol use and related problems. Our study is the first in the literature to show that solitary predrinking helps explain the well-documented association between SA and alcohol-related problems. These findings may inform etiological models and clinical interventions, suggesting that SA-risk for problem drinking begins even before the party starts.

Is being mindful associated with reduced risk for internally-motivated drinking and alcohol use among undergraduates?

Mindfulness encompasses four core skills: observing, describing, acting with awareness, and accepting without judgment; which aim to increase ones awareness, tolerance, and acceptance of internal experiences (Baer et al., 2004). Despite promising clinical results that mindfulness reduces alcohol craving and relapse, complementary etiological research is underdeveloped. Theory suggests that those who are motivated to drink to change internal states (reduce negative/increase positive affect) are at risk for elevated alcohol use. The ability to accept ones affective state should preclude internally-motivated drinking, and thus, elevated alcohol use. The purpose of this study was to parse out which mindfulness skills are central to alcohol use. We hypothesized that accepting without judgment would be a unique negative predictor of internally-motivated drinking (drinking for coping and enhancement motives) and alcohol use. Students (N=76) completed self-report measures of past month alcohol use and four motives for drinking: to cope, for enhancement, to conform, and for social reasons. Partially supporting our hypotheses, accepting without judgment was negatively associated with drinking for coping motives, but was unassociated with drinking for enhancement motives. Interestingly, acceptance without judgment was negatively associated with drinking for conformity motives (to reduce social rejection). Unexpectedly, acting with awareness, but not accepting without judgment, was a negative predictor of alcohol use. Our findings suggest that interventions aimed at reducing coping- and conformity-motivated drinking and alcohol use by young adults may benefit from incorporating mindfulness skills training (i.e., accepting without judgment; acting with awareness).

Impulsivity increases risk for coping-motivated drinking in undergraduates with elevated social anxiety☆

According to theory, those high in social anxiety (SA) are at risk for drinking alcohol for coping and conformity motives, which in turn lead to alcohol use and related problems. Empirical tests of this risk pathway in non-clinical samples have produced mixed results. Although those high on SA may drink to cope with anxiety and to reduce the likelihood of social rejection, they may also avoid drinking for fear of embarrassing themselves when intoxicated. Central to alcohol use by those high in SA is a temporary disregard of alcohols potentially negative consequences. Accordingly, we hypothesized that SA would positively predict alcohol use and problems, but only at high levels of impulsivity (IMP). We expected these interactive effects to be mediated by coping and conformity motives. Undergraduates (N = 461) completed self-reports. Partially supporting hypotheses, IMP moderated the association between SA and alcohol-related problems (but not use), such that SA predicted problems only at high IMP. This interactive effect was mediated by coping (but not conformity) motives, such that SA positively predicted coping motives (especially at high IMP), which in turn predicted problems. Results suggest that IMP and coping motives clarify SA-related drinking. Clinical interventions may consider targeting IMP.

Interactive Effects of the BIS and the BAS on Trajectories of Alcohol Misuse after University Graduation.

Reinforcement Sensitivity Theory predicts that those with a strong behavioral inhibition system (BIS) likely experience considerable anxiety and uncertainty during the transition out of university. Accordingly, they may continue to drink heavily to cope during this time (a period associated with normative reductions in heavy drinking), but only if they also have a strong behavioral approach system (BAS) to enhance the anxiolytic effects of drinking. The purpose of this study was to test this hypothesis. Participants completed online measures prior to and at 3-month intervals over the course of the year following graduation. As hypothesized, results showed that an elevated BIS predicted impeded maturing out, but only when the impulsivity facet of BAS was also elevated. In contrast, a strong BIS predicted rapid maturing out if BAS impulsivity was weak. Study findings advance our understanding of BIS-related alcohol misuse trajectories in young adulthood and provide direction for clinical interventions.

Exploring physical activity preferences across the lifespan

ABSTRACT This investigation of 1885 participants focused on patterns of physical activity (PA) preferences across the lifespan. The first part involved an exploratory factor analysis (EFA) of a 50-item measure of PA preferences, while the second examined differences in PA factor scores across five age groups: teens, 20s, 30s, 40s, and 50+. EFA results suggested an eight-factor (oblique rotation) solution; the factors labelled were: yoga and stretching, non-gym leisure activities, martial arts, class training, outdoor activities, group cardio, weight training, and competitive sports. Age group differences were examined through univariate analysis of variance for each of the eight factors. Three factors showed no significant age group differences, while five others manifested significant age group differences with significant linear trends, such that older groups expressed lower preference levels. Results give rise to concern regarding diminishing activity-related avenues for personal enjoyment and satisfaction of aging individuals.

Solitary gambling mediates the risk pathway from anxiety sensitivity to excessive gambling: Evidence from a longitudinal ecological momentary assessment study.

Anxiety and gambling problems co-occur at high rates. Social learning theory (SLT) suggests that people high in anxiety engage in excessive gambling to reduce negative affect. Because anxiety sensitivity (AS) is a vulnerability factor associated with addictive behaviors, it is important to identify mediators in this high-risk pathway. Emerging research shows that social context mediates associations between anxiety vulnerability and addictive behaviors. This literature shows that anxiety-prone people are at increased risk for substance problems because they engage in frequent solitary substance use. Theory would predict a similar pathway to gambling problems, but this remains to be tested. Accordingly, this study aimed to examine solitary gambling as an explanatory variable in the anxiety pathway to gambling problems. We used a longitudinal ecological momentary assessment (EMA) design. After completing baseline measures, young adults (N = 108) were asked to report daily on their gambling behavior over a 30-day period. Bias corrected bootstrapped confidence intervals (CI) supported 1 hypothesized indirect effect from baseline AS (Time 1) to EMA time spent gambling (Time 2) via EMA solitary gambling (Time 2; B = 0.019, 95% CI [0.002, 0.045]). This suggests that emerging adults with high levels of AS at baseline engaged in frequent solitary gambling over the 30-day EMA sampling period, which in turn predicted more time spent gambling over this same time period. Our results show that solitary gambling mediates the relation between anxiety vulnerability and excessive gambling. Understanding how social context relates to excessive gambling can help create interventions to reduce solitary gambling among anxiety-prone individuals.

Testing the Efficacy of an Online Self-Help Treatment for Comorbid Alcohol Misuse and Emotional Problems in Young Adults: A Randomized Controlled Trial (RCT) (Preprint)

Background Alcohol misuse and emotional problems (ie, depression and anxiety) are highly comorbid among Canadian young adults. However, there is a lack of integrated, accessible, and evidence-based treatment options for these young adults. Objective The main goal of this study is to develop and test the efficacy of an integrated, online self-help program designed to target both alcohol misuse and emotional problems. Methods A two-arm randomized controlled trial design will be used to compare the efficacy of the online integrated treatment to a psychoeducational control group. A target sample of 214 participants will be recruited and randomly assigned to either condition. The integrated treatment will last 8 weeks, and participants will work through 12 modules. Modules will incorporate content based on principles of cognitive behavioral therapy and motivational interviewing. Participants in the control group will receive links to psychoeducational resources and will have access to the full treatment after follow-up. The primary outcome will be the number of Canadian standard drinks consumed in the week leading up the assessment. Secondary outcomes of interest include symptoms of depression, anxiety, alcohol-related problems, quality of life, and use of other drugs. Assessments will be completed at 3 time-points: at baseline, at the end of treatment (ie, 8 weeks), and at follow-up (ie, 24 weeks). Upon completion, data will be analyzed using generalized linear mixed models. Results Data collection began in June 2018 and will continue until January 2020. Final study results will be submitted for publication by July 2020. Conclusions Currently, there are no integrated treatments designed to target alcohol misuse and the range of emotional problems experienced by young adults. This research stands to provide an effective, accessible (ie, Web-based), and feasible option to treat the many struggling young adults in this country. Trial Registration ClinicalTrials.gov ID NCT03406039; https://clinicaltrials.gov/ct2/show/NCT03406039 (Archived by WebCite at http://www.webcitation.org/72fDefnrh) Registered Report Identifier PRR1-10.2196/11298