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Matthias Dr. Schüller

Bayer

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Publication

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FEBS Letters | 1991

Antiviral activity of some natural and synthetic sugar analogues

Richard T.C. Huang; Ellen Dietsch; Oswald Lockhof; Matthias Dr. Schüller; Werner Reutter

A number of natural and synthetic sugar analogues have been tested for their antiviral activity, using an influenza virus strain as a model. Hemagglutinating titres (HA) and cytopathic effect (CPE) were surveyed to estimate the virus production. It was found that introduction of the benzyl group into these sugars generally causes them to become antivirally active. Substitution with methyl, acetyl, uridyl and thiocyanyl groups or derivatization with azido, isopropylidene and benzylidene groups were without effect. All sugars containing the 2‐deoxy‐2‐acetamido group were inactive.

Archive | 1988

Methods for treating viruses in patients by administering 2-hydroxymethylene-3,4,5-trihydroxypiperidines

Horst Boshagen; Bodo Junge; Günther Dr. Kinast; Matthias Dr. Schüller; Jurgen Stoltefuss; Arnold Paessens

Archive | 1986

3-Amino-4,5-dihydroxypiperidines, process for their preparation and their use

Günther Dr. Kinast; Matthias Dr. Schüller; Theo Dr. Schröder

Archive | 1988

Use of 2-hydroxymethylene-3,4,5-trihydroxypiperidines as antiviral agents

Horst Boshagen; Bodo Junge; Günther Dr. Kinast; Matthias Dr. Schüller; Jurgen Stoltefuss; Arnold Paessens

Archive | 1991

Desoxynojirimycin derivatives, process for their preparation and their use in drugs

Wolfgang Dr Roeben; Oswald Lockhoff; Kai Rossen; Matthias Dr. Schüller; Jürgen Dipl.-Ing. Stoltefuss; Arnold Paessens

Archive | 1988

Chiral 6-hydroxymethyl-3-amino-4,5-dihydroxy piperidines, their intermediates, processes for their preparation and their use

Matthias Dr. Schüller; Horst Boshagen; Fred-Robert Heiker

Archive | 1991

Medicines containing as a mixture interferon and 1-desoxy-piperidinoses, process for their manufacture and their use

Arnold Paessens; Matthias Dr. Schüller

Archive | 1991

Neue Desoxynojirimycinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln

Wolfgang Dr Roeben; Oswald Lockhoff; Kai Rossen; Matthias Dr. Schüller; Jürgen Dipl.-Ing. Stoltefuss; Arnold Paessens

Archive | 1991

ANTIVIRAL DEOXYNOJIRIMYCIN DERIVATIVES

Wolfgang Dr Roeben; Oswald Lockhoff; Kai Rossen; Matthias Dr. Schüller; Jurgen Stoltefuss; Arnold Paessens

Archive | 1988

N-substituted derivatives of 1-desoxynojirimycine and 1-desoxymannonojirimycine, process for their preparation and their use as pharmaceuticals.

Horst Boshagen; Bodo Junge; Arnold Paessens; Matthias Dr. Schüller

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Horst Boshagen

Bayer

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Arnold Paessens

Safety Pharmacology Society

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Bodo Junge

Bayer

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Günther Dr. Kinast

Bayer

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Jurgen Stoltefuss

Bayer

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Kai Rossen

Bayer

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Oswald Lockhoff

Bayer

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Wolfgang Dr Roeben

Bayer

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Jürgen Dipl.-Ing. Stoltefuss

Bayer

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Ellen Dietsch

Free University of Berlin

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