Maurício Abujamra Nascimento
State University of Campinas
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Featured researches published by Maurício Abujamra Nascimento.
Ophthalmologica | 2003
David Leonardo Cruvinel Isaac; Vinícius Coral Ghanem; Maurício Abujamra Nascimento; Marcelo Torigoe; Newton Kara-José
Purposes: To evaluate the main factors related to visual outcome after open globe injuries (excluding intraocular foreign bodies). Methods: Retrospective study analyzing consecutive ocular lacerations, primarily repaired in this institution, between January 1993 and January 2000. Of the 364 cases, 283 (77.75%) lacerations were statistically analyzed, correlating the preoperative variables with the postoperative visual acuity (VA). Excluded from this study were all patients with less than 6 months of follow-up, previous ocular surgery, unreliable information on VA, intraocular foreign bodies and endophthalmitis. When a bilateral injury was detected, only 1 eye was randomly chosen. Results: It was observed, after statistical analysis (multivariate analysis), that the most important factors related to postoperative poor VA (less than 20/100) were: the length of the laceration, the elapsed time between the injury and the surgery and the presence or absence of vitreous loss, cataract (lens damage), hyphema, laceration posterior to rectus muscle insertion and retinal detachment. Conclusion: With this study, it was possible to point out the most important factors related to visual prognosis in open globe injuries. The results found are similar to results previously reported.
American Journal of Ophthalmology | 2014
João Paulo Fernandes Felix; Rodrigo Pessoa Cavalcanti Lira; Rafael Santos Zacchia; Jaqueline Toribio; Maurício Abujamra Nascimento; Carlos Eduardo Leite Arieta
PURPOSE To compare the effects of trimethoprim-sulfamethoxazole vs placebo in reducing the risk of recurrences of Toxoplasma gondii retinochoroiditis. DESIGN Single-center, prospective randomized double-masked clinical trial. METHODS A total of 95 patients from Campinas, Brazil, with active recurrent Toxoplasma gondii retinochoroiditis were included. The initially active toxoplasmosis lesions were successfully treated in all cases using trimethoprim-sulfamethoxazole (800 mg/160 mg) twice daily for 45 days. Subsequently, 5 patients dropped out of the study. The remaining patients were randomized to Group 1 (trimethoprim/sulfamethoxazole tablet every 2 days) or Group 2 (identical placebo tablet every 2 days). Randomization was 1:1, was stratified by sex, and used block sizes of 4. The primary outcome was recurrent toxoplasmosis retinochoroiditis within 1 year, and the secondary outcome was a 1-year change in best-corrected visual acuity (BCVA) (ETDRS chart). RESULTS The incidence of recurrent toxoplasmosis retinochoroiditis within 12 months was 0 of 46 (0%) and 6 of 47 (12.80%) in the trimethoprim-sulfamethoxazole and placebo groups, respectively (P = .026). Visual acuity improvements in the 2 groups were similar. No treatment-limiting toxicity was observed. CONCLUSIONS Trimethoprim/sulfamethoxazole therapy resulted in a 100% reduction in the recurrence of Toxoplasma gondii retinochoroiditis over 1 year of treatment.
Archives of Ophthalmology | 2010
Rodrigo Pessoa Cavalcanti Lira; Iuuki Takasaka; Carlos Eduardo Leite Arieta; Maurício Abujamra Nascimento; Roberto Caldato; Heitor Panetta
OBJECTIVE To compare the reattachment rate and visual acuity results among patients with rhegmatogenous retinal detachment who underwent scleral buckle surgery with retinopexy by intraoperative cryotherapy (cryopexy) vs postoperative (1 month later) laser photocoagulation (laserpexy). METHODS Eighty-six patients with rhegmatogenous retinal detachment scheduled for scleral buckle surgery were randomly assigned to the cryopexy or laserpexy group. MAIN OUTCOME MEASURES The primary outcome was the 1-week reattachment rate. Other outcome measures included later reattachment rate (1 month and 6 months), best-corrected visual acuity, rate of subsequent operations, and postoperative complications. RESULTS The 1-week, 1-month, and 6-month anatomical success rates were similar in the 2 groups: 93% (40 patients), 100%, and 100% in the cryopexy group and 95% (41 patients), 100%, and 100% in the laserpexy group, respectively. Three patients in the cryopexy group and 2 in the laserpexy group underwent 1 additional rhegmatogenous retinal detachment surgery (pars plan vitrectomy) after primary failure at 1-week follow-up. The types of postoperative complications were similar in both groups, except for eyelid edema. Visual recovery was slower in the cryotherapy group, but the difference in visual acuity after 6 months was not significant. CONCLUSIONS In patients with uncomplicated retinal detachment, both techniques of retinopexy have shown satisfactory anatomical and functional success. Laserpexy offers faster visual acuity recuperation with fewer postoperative complications but requires a second intervention and costs more than cryotherapy. APPLICATION TO CLINICAL PRACTICE Laserpexy is a successful alternative to cryopexy in creating chorioretinal adhesion for scleral buckle surgery. TRIAL REGISTRATION clinicaltrials.gov Identifier: NCT01068379.
Revista De Saude Publica | 2001
Rodrigo Pessoa Cavalcanti Lira; Maurício Abujamra Nascimento; Edméa Rita Temporini; Newton Kara-José; Carlos Eduardo Leite Arieta
Com o objetivo de verificar as causas de suspensao de cirurgia de catarata e sugerir medidas para melhorar a eficiencia do servico prestado a populacao, foi realizado um estudo transversal no servico de oftalmologia de um hospital universitario do Estado de Sao Paulo. A amostra foi composta por 200 individuos. A media de idade foi de 68± 11,4 anos. As causas de suspensao de cirurgia foram: condicao clinica desfavoravel (23,1%); horario cirurgico insuficiente (35,9%); e nao comparecimento do paciente (41%). Os fatores causadores foram, majoritariamente, as razoes sociais e o funcionamento do hospital.
Current Eye Research | 2004
Maurício Abujamra Nascimento; Rodrigo Pessoa Cavalcanti Lira; Paulo Henrique Limeira Soares; Nolvar Spessatto; Newton Kara-José; Carlos Eduardo Leite Arieta
Purpose. The aim of this prospective randomized clinical trial was to investigate whether routine medical testing before cataract surgery reduced the rate of ocular surgical complications and to study its impact on visual acuity outcome. Methods. The study was carried out in an academic medical center in Brazil, at State University of Campinas, between 10 February 2000 and 10 January 2001. The scheduled cataract operations were randomly assigned to one of two groups: 1) to be preceded by routine medical testing (the “routine-testing group”) or 2) not to be preceded by routine medical testing (the “selective-testing group”). If the patient was assigned to the selective-testing group, it was requested that no preoperative testing be performed unless the patient presented with a new or worsening medical problem that would warrant medical evaluation with testing. In the case of patients assigned to the routine-testing group, three tests were requested: a 12-lead electrocardiogram, a complete blood count, and measurements of serum glucose. Ocular surgical complications, preoperative and postoperative best-corrected visual acuity were recorded on a standardized form. Results. The sample of 1025 patients scheduled to undergo cataract surgery was comprised of 512 assigned to the routine-testing group and of 513 assigned to the selective-testing group. The two groups had similar proportions of operations canceled and not subsequently rescheduled, 2% in each group. The cumulative rate of ocular surgical complications was similar in the two groups, 20.5% in the routine-testing group and 19.3% in the selective-testing group (p = 0.624). The preoperative and the postoperative best-corrected visual acuity were similar in both groups (p = 0.999 in the former and p = 0.664 in the latter). Conclusions. The results of this study suggest that routine medical testing before cataract surgery did not reduce the rate of ocular surgical complications and did not influence visual acuity outcome.
Revista De Saude Publica | 2003
Rodrigo Pessoa Cavalcanti Lira; Maurício Abujamra Nascimento; Newton Kara-José; Carlos Eduardo Leite Arieta
OBJETIVO: Determinar a prevalencia de resultados anormais numa rotina de exames pre-operatorios para facectomias e sua influencia na ocorrencia de complicacoes clinicas perioperatorias. METODOS: Estudo prospectivo desenvolvido em um centro medico academico no Brasil, com uma amostra de 746 pacientes, selecionados entre indicados para cirurgia de catarata. Para todos os pacientes foram solicitados eletrocardiograma, hemograma completo e glicemia de jejum, alem de uma avaliacao clinica. Foram excluidos do estudo pacientes com menos de 40 anos de idade, pacientes submetidos previamente a cirurgia ocular, pacientes com indicacao de anestesia geral, ou pacientes que sofreram infarto agudo do miocardio ate tres meses antes da cirurgia. Eventos medicos intra-operatorios foram registrados numa ficha de protocolo. Para analise, utilizou-se do teste de Fisher e analise de variância (ANOVA). RESULTADOS: Na amostra de 746 pacientes, 405 (54,3%) eram homens. A idade media foi de 66,6±11,6 anos. Ocorreram complicacoes intra-operatorias em 71 (9,5%) pacientes. Houve resultados anormais em 13,5% (101 pacientes) das dosagens de hemoglobina e em 16,6% (124) das dosagens de glicemia de jejum. Em relacao aos eletrocardiogramas, foram constatadas anormalidades em 46,6% (348) dos individuos. Houve maior prevalencia de eletrocardiogramas com anormalidades em pacientes com complicacoes clinicas perioperatorias (p=0,02). Nao existiu diferenca estatisticamente significativa nas dosagens de hemoglobina (14,0±1,6 g/dL em pacientes sem complicacoes intra-operatorias e 14,3±1,3 g/dL em pacientes com complicacoes - p=0,150) e nas de glicemia de jejum (104±29 mg/dL em pacientes sem complicacoes e 105±41 mg/dL em pacientes com complicacoes - p=0,850). CONCLUSOES: Dentro da rotina investigada de exames pre-operatorios para facectomia, apenas os resultados anormais presentes no eletrocardiograma estiveram associados a ocorrencia de complicacoes durante o periodo de perioperatorio.
Sao Paulo Medical Journal | 2004
Paulo de Tarso Ponte Pierre-Filho; Alessandra Maria Mont'Alverne Pierre; Maurício Abujamra Nascimento; Ana Maria Marcondes
CONTEXT Retinal vein thrombosis is most common in old people, and is often associated with systemic vascular disease. One of its rare systemic causes is protein S deficiency. CASE REPORT A case of a 21-year-old woman with retinal vein prethrombosis associated only with protein S deficiency is described. She presented with acutely reduced visual acuity and a central scotoma in her left eye. Warfarin therapy was initiated, and complete improvement in ophthalmoscopic findings was subsequently observed. This case illustrates that protein S deficiency is a factor that should be considered in cases of retinal vein occlusion, particularly in young patients.
Indian Journal of Ophthalmology | 2010
Rodrigo Pessoa Cavalcanti Lira; Maurício Abujamra Nascimento; Carlos Eduardo Leite Arieta; Luis Eduardo Mateus Duarte; Fabio Endo Hirata; Wilson Nadruz
Incidence of preoperative rise in blood pressure (BP) in cataract surgery among hypertensive and normotensive patients. Objective: To study the incidence of preoperative rise in BP in cataract surgery among normotensive individuals and hypertensive patients with historic good BP control in a population without other major chronic diseases. Settings: Ophthalmology Service of a University Hospital. Materials and Methods: A prospective study with 822 patients older than 40 years of age, with cataract surgery indication, and without major chronic diseases other than hypertension. The patients were divided in two groups: hypertensive and normotensive. Preoperative data, physical exams and medical adverse events were recorded in an evaluation questionnaire. Results: The sample included 427 normotensive (52%) and 395 hypertensive patients (48%). The two groups had similar proportions of operations that were cancelled and not subsequently rescheduled, 2% (eight patients) in each group. The incidence of preoperative rise in BP was 3.7% in the normotensive group and 10.9% in the hypertensive group (P < 0.001). Conclusion: Hypertensive patients with historic good BP control and without other major co-morbidities present a larger incidence of preoperative rise in BP than normotensive individuals in cataract surgery.
SciELO | 2004
Carlos Eduardo Leite Arieta; Maurício Abujamra Nascimento; Rodrigo Pessoa Cavalcanti Lira; Newton Kara-José
The objective of this clinical trial was to determine the frequency of medical tests considered unnecessary in routine preoperative evaluation for cataract surgery. Unnecessary costs with these tests were also evaluated. For patients assigned to the selective testing group, it was requested that no preoperative testing be performed unless the patient presented a new or worsening medical problem warranting medical evaluation with testing. For patients assigned to the routine testing group, three tests were requested: a 12-lead electrocardiogram, complete blood count, and serum glucose level. The costs of tests considered unnecessary were calculated. The sample of 1,025 patients consisted of 512 assigned to the routine testing group and 513 to the selective testing group. Cumulative rate of medical events was similar in the two groups (p=0.923). The selective group underwent 60.7% fewer tests. The results suggest that selective preoperative testing in cataract surgery does not harm patients in terms of peri-operative clinical complications and also represents a significant cost reduction compared to routine testing.
Arquivos Brasileiros De Oftalmologia | 2003
Vinícius Coral Ghanem; David Leonardo Cruvinel Isaac; Maurício Abujamra Nascimento; Rosane Silvestre de Castro; Newton Kara-José
PURPOSES: 1) To verify the impact of the creation of the Single Technical Record (STR) at the University of Campinas (Unicamp) Hospital das Clinicas, on the preservation period of corneas which were used in elective penetrating keratoplasties, and 2) to compare the primary failure incidence in cornea penetrating keratoplasties regarding the periods before and after the creation of STR. METHODS: A retrospective study was conducted at the Unicamp Hospital, which evaluated 15 consecutive cornea penetrating keratoplasties between January 1st and April 30th, 2000 and 24 consecutive penetrating keratoplasties between May 1st and September 20th of the same year (corneas under the control of the STR), totaling 39 keratoplasties. RESULTS: The mean time between cornea preparation and transplantation was 3.8 days (±1.78) in the period before STR creation, and 6.0 days (±2.97) after STR creation, representing a 36.7% increase in the preservation time. There was a statistically significant difference (p=0.02) between the two groups. No corneal primary failure was observed among the 39 transplanted patients in both groups. CONCLUSION: Based on the results of this study, it can be concluded that this new concept of the State Transplantation System has caused a statistically significant increase in the conservation period of corneas, which may reduce the period of a clear transplant due to an increased loss of endothelial cells, as well as increase the primary failure incidence or result in a high number of corneas that cannot be used due to having exceeded the preservation time recommended by the literature.