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Dive into the research topics where Maximilian Sixt is active.

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Featured researches published by Maximilian Sixt.


Chemie Ingenieur Technik | 2018

Quality-by-Design (QbD) process evaluation for phytopharmaceuticals on the example of 10-deacetylbaccatin III from yew

Lukas Uhlenbrock; Maximilian Sixt; Jochen Strube

The focus of pharmaceutical product development lies on assuring excellent product quality at the end of a cost-efficient process. The Quality-by-Design (QbD) concept shifts the focus from quality assurance through testing to quality control by process understanding, resulting in very robust processes with high quality product[FDA 2006, ICH 2009, 2009]. QbD was originally intended by authorities for biologics, where product quality proven completely by analytics is not desired. Product quality has to be controlled by means of appropriate processes and operations as well.


Comptes Rendus Chimie | 2016

Process design for integration of extraction, purification and formulation with alternative solvent concepts

Maximilian Sixt; I. Koudous; Jochen Strube


Processes | 2017

Systematic and Model-Assisted Evaluation of Solvent Based- or Pressurized Hot Water Extraction for the Extraction of Artemisinin from Artemisia annua L.

Maximilian Sixt; Jochen Strube


Resource-Efficient Technologies | 2017

Pressurized hot water extraction of 10-deacetylbaccatin III from yew for industrial application

Maximilian Sixt; Jochen Strube


Processes | 2018

Systematic and Model-Assisted Process Design for the Extraction and Purification of Artemisinin from Artemisia annua L.—Part I: Conceptual Process Design and Cost Estimation

Maximilian Sixt; Axel Schmidt; Fabian Mestmäcker; Maximilian Huter; Lukas Uhlenbrock; Jochen Strube


Chemical Engineering Research & Design | 2018

Integrating crystallization with experimental model parameter determination and modeling into conceptual process design for the purification of complex feed mixtures

Martin Lucke; I. Koudous; Maximilian Sixt; Maximilian Huter; Jochen Strube


Processes | 2018

Systematic Design and Evaluation of an Extraction Process for Traditionally Used Herbal Medicine on the Example of Hawthorn (Crataegus monogyna JACQ.)

Maximilian Sixt; Jochen Strube


Processes | 2018

Systematic and Model-Assisted Process Design for the Extraction and Purification of Artemisinin from Artemisia annua L.—Part II: Model-Based Design of Agitated and Packed Columns for Multistage Extraction and Scrubbing

Axel Schmidt; Maximilian Sixt; Maximilian Huter; Fabian Mestmäcker; Jochen Strube


Processes | 2018

Systematic and Model-Assisted Process Design for the Extraction and Purification of Artemisinin from Artemisia annua L.—Part III: Chromatographic Purification

Fabian Mestmäcker; Axel Schmidt; Maximilian Huter; Maximilian Sixt; Jochen Strube


Comptes Rendus Chimie | 2018

In-line Raman spectroscopy and advanced process control for the extraction of anethole and fenchone from fennel (Foeniculum vulgare L. MILL.)

Maximilian Sixt; Gennadi Gudi; Hartwig Schulz; Jochen Strube

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Jochen Strube

Clausthal University of Technology

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Maximilian Huter

Clausthal University of Technology

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I. Koudous

Clausthal University of Technology

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Lukas Uhlenbrock

Clausthal University of Technology

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Martin Lucke

Clausthal University of Technology

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