Mayur Danny I. Gohel

Impact of Fabric Moisture Transport Properties on Physiological Responses when Wearing Protective Clothing

This purpose of this study was to investigate the impact of fabric moisture transport properties (MTP) on physiological responses when wearing protective clothing. Ten healthy subjects wore two kinds of personal protective equipment (PPE) ensembles and exercised on a treadmill, worked on a computer, and moved a mannequin in an environment that simulated where health carers work. PPE1 consisted of cotton underwear and 100% polyethylene outerwear. PPE2 consisted of cotton underwear with moisture management function and outerwear made of waterproof breathable fabric. The results showed that there were significantly higher cumulative one-way transport capacity, liquid moisture management capacity, and wetting time in PPE2 than in PPE1 underwear. There was significantly higher water vapor permeability (WVP) in PPE2 than in PPE1 outerwear. Deep ear canal temperature, mean skin temperature, and chest wall skin and clothing microclimates (temperature and humidity) were significantly lower with PPE2 than PPE1. The level of plasma oxygen saturation was significantly higher with PPE 2 than PPE1. In the present study, due to the MTP of the fabrics, liquid sweat transferred from the skin surface to the opposite surface quickly and speeded up the processes of evaporation and heat dissipation. It was concluded that the fabrics MTP, when incorporated into protective clothing, is the main physiological mechanism for reduced heat stress.

Telomerase-Associated Apoptotic Events by Mushroom Ganoderma lucidum on Premalignant Human Urothelial Cells

The chemopreventive effects of Ganoderma lucidum was tested, using a tumorigenic transformable human urothelial cell (HUC-PC) model. These in vitro data show that G. lucidum can inhibit the viability and growth of HUC-PC. This could be explained by a concomitant induction of apoptosis and inhibition of telomerase activity. Significant exteriorization of phosphatidylserine was detected by Annexin-V on cell surface, and the cells subsequently lost membrane integrity for uptake of 7-amino-actinomycin D dye. Additionally, the levels of hydrogen peroxide and 8-hydroxy-2′-deoxyguanosine (8-OHdG) production of the apoptotic cells were significantly increased. The induction of apoptosis and suppression of telomerase activity help to explain the anti-HUC-PC growth properties; however, the induction of oxidative stress requires further study. This study strongly suggests that G. lucidum is a potential source of chemopreventive agents for bladder cancer based on its effectiveness in controlling the premalignant urothelial cell growth and carcinogen-induced transformation.

Urinary glycosaminoglycans and glycoproteins in a calcium oxalate crystallization system.

This study measures the effects of total urinary glycosaminoglycans (GAGs), glycoproteins (GPs) and individual GAGs on the nucleation rates (Bo), growth rates (G) and suspension densities (Mт) of calcium oxalate (CaOx) crystallization by the mixed suspension mixed product removal (MSMPR) system. Total urinary GAGs, glycoproteins and individual GAGs including heparan sulfate (HS), chondroitin sulfate (CS) and Hyaluronic acid (HA) were added into the artificial urine (AU) and then introduced into the MSMPR test chamber and the crystal sizes and numbers were analyzed by a particle counter. The effects of added GAGs and GPs on CaOx crystallization were reflected by the changes on the crystallization indexes including the Bo, G and Mт of CaOx that were calculated based on the crystal size and numbers. Total urinary GAGs showed no statistical significance on CaOx crystallization. However, individual GAGs such as HA, CS and HS enhanced Bo and suppressed the G when measured individually. CS and HS enhanced the Mт while HA shown no significant change in the Mт of CaOx. Total urinary GPs showed an increase in the G and Mт of crystals. Although total urinary GAGs showed no statistically significant effect on CaOx crystallization, individual GAGs (CS, HS) promoted the CaOx crystallization by increasing the suspension density of smaller crystals, indicative of reduced risk of stones while HA showed no significance in the M(T) of CaOx formed. Urinary GPs indicated increased sizes and M(T) suggesting larger crystals and/or aggregates.

Effects of fabric surface energy on human thermophysiological responses during exercise and recovery

AbstractThe present paper reports a study on influences of fabric surface energy of cotton and polyester garments on clothing microclimates and human thermophysiological responses during intermittent exercise and recovery. Eight healthy males wearing the garments prepared performed exercises and rest according to the following protocol: rest for 30 min, run on treadmill for total 60 min of three sessions with different intensity and duration, and then sit quietly for 30 min for recovery, all at 30 °C and relative humidity of 30 %, while the microclimate humidity (Hmc) and temperature (Tmc), the clothing outside surface humidity (Hco) and temperature (Tco), the skin temperatures and ear canal temperature (Tear_canal) were measured. The garments are made of: (a) hydrophilic and hydrophobic cotton knitted fabrics, and (b) hydrophilic and hydrophobic polyester knitted fabrics. During and after exercise, for cotton, hydrophilic garment resulted in significant lowerΔHmc, ΔHco, ΔTmc during recovery, higher

Mechanism of pajama material on stratum corneum water content under mild cold conditions: explored by hierarchical linear regression

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Anticancer Effects of Ganoderma lucidum: A Review of Scientific Evidence

, lowerΔTear_canal andΔTforehead. For polyester, hydrophilic garment resulted in significantly lowerΔHco, ΔTco, higher

Evaluation on Masks with Exhaust Valves and with Exhaust Holes from Physiological and Subjective Responses

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