Md. Chanmiya Sheikh

Crystal structure ofS-hexyl (E)-3-(4-methylbenzylidene)dithiocarbazate

In the title compound, C15H22N2S2, the dithiocarbazate group adopts an E conformation with respect to the C=N bond of the benzylidene moiety. In the crystal, molecules are linked by pairs of N—H⋯S hydrogen bonds, forming inversion dimers with an R 2 2(8) ring motif. The dimers are linked via C—H⋯π interactions, forming chains propagating along [100].

Crystal structure of bis-[S-hexyl 3-(4-methyl-benzyl-idene)di-thio-carbazato-κ(2) N (3),S]palladium(II).

The whole molecule of the title complex, [Pd(C15H21N2S2)2], is generated by twofold rotational symmetry. The palladium(II) atom exhibits a square-planar coordination geometry, and is located on the crystallographic twofold axis that induces a cis configuration of the N,S chelating ligands. In the crystal, molecules stack along the c-axis direction and there are no significant intermolecular interactions present. The structure was refined as an inversion twin with a final BASF parameter of 0.34 (2).

Crystal structure ofS-hexyl (E)-3-(4-methoxybenzylidene)dithiocarbazate

In the title compound, C15H22N2OS2, the dithiocarbazate group adopts an EE conformation with respect to the C=N bond of the benzylidene moiety. The hexyl side chain adopts an extended conformation and the C—S—C—C torsion angle is −93.36 (13)°. In the crystal, inversion dimers linked by pairs of N—H⋯S hydrogen bonds generate R 2 2(8) loops.

Lossen-type rearrangement products in the reaction of N-(phthalimidoyloxy)-3-phenylpropionate and -tosylate with benzyl alcohol

This paper reports the reaction of N-(phthalimidoyloxy)-3-phenylpropionate (2a) and -tosylate (6) with benzyl alcohol as a nucleophile to afford the products via Lossen-type rearrangement. To study the scope of this reaction mechanism, we also studied the reaction of several N-sulfonyloxyimide derivatives with benzyl alcohol under similar conditions and found that the same types of products were obtained in high yields.

Crystal structure of S-octyl (E)-3-(4-meth­oxy­benzyl­idene)di­thio­carbazate

As already observed in similar molecules, the dithiocarbazate group in the title compound, C17H26N2OS2, adopts an EE configuration with respect to the C=N bond of the benzylidene moiety. In the crystal, molecules are connected into inversion dimers by pairs of N—H⋯S hydrogen bonds. The dimers are linked by weak π–π interactions, with centroid-to-centroid distances of 3.723 (11) Å, forming chains parallel to [110].

Thermal Reactions of β-Hydroxysulfides Bearing Benzothiazole: Sulfenic Acid Trapping via a Spiro Intermediate

Benzothiazolyl 2-hydroxyethyl sulfoxide (1a) was found to afford bis[2-(2-oxobenzotiazolyl)-ethyl] disulfide (2a) in the presence of DBU at rt. 2a was formed by the condensation of corresponding sulfenic acid intermediate. Thermolyses of 1a in the presence of ethyl propiolate at 60–140°C were carried out to succeed to trap sulfenic acid 6a as an intermediate. Trapping of 2-benzothiazolyloxyenthanesulfenic acid (6a) revealed that the thermal reaction proceeded via a five-membered spiro intermediate 5a.

Bischelated complexes of a dithiocarbazate N,S Schiff base ligand: synthesis, characterization and antimicrobial activities

The N,S bidentate proligand S-hexyl-β-N-(4-methoxybenzylidene)dithiocarbazate (HL), obtained by condensation of S-hexyldithiocarbazate with 4-methoxybenzaldehyde, has been used to synthesize six metal complexes, namely NiL2, CuL2, ZnL2, CdL2, PdL2 and PbL2, which have been characterized by physicochemical techniques and spectroscopic methods. Single crystal structural analyses for NiL2, CuL2 and PdL2 show that these are square-planar complexes with each metal bischelated by the Schiff base in its deprotonated monoanionic form. In all three cases, the ligands show a trans configuration, although they crystallize in different space groups. All the metal complexes with the exception of the nickel derivative show a significant decrease in fluorescence intensity with respect to the free proligand HL. Free HL and all six complexes were tested for antibacterial activity against three pathogenic gram-negative organisms. The metal complexes show moderate although diverse activities; however, free HL as well as the copper(II) complex did not reveal any antibacterial activity against the tested organisms.

Synthesis, characterization and antimicrobial activity of a bidentate NS Schiff base of S-benzyl dithiocarbazate and its divalent complexes

Abstract The reaction of S-benzyl dithiocarbazate (SBDTC) with 2,4,5-trimethoxybenzaldehyde afforded a bidentate NS Schiff base 1 (benzyl-3-N-(2,4,5-trimethoxyphenylmethylenehydrazine carbodithioate), which on further reaction with M(II) (where M(II) = nickel(II), zinc(II), palladium(II) and copper(II)) in ethanol under reflux yielded bis-chelated inner complexes [ML2] 2–5 with deprotonated L. The ligand and its complexes were characterized by physicochemical techniques, viz., molar conductance, magnetic susceptibility measurement, IR, NMR, UV–Vis and mass spectroscopic techniques. The crystal structures of 1 and 5 were also determined by single-crystal X-ray crystallography. The crystal structure analysis showed that the ligand exists in its thione tautomeric form. In the complexes, each of the two deprotonated ligands chelated the metal ions through the β-nitrogen and the thione sulfur forming five-membered rings. The copper(II) complex (5) exhibited a square-planar geometry, where the two N2S2 chromophores are arranged trans. All the compounds showed strong antibacterial activity against S.-β-hemolyticus, Klebsiella pneumoni, and Escherichia coli. The compounds also showed strong antifungal activity against Aspergillus fumigatus, Aspergillus niger, Aspergillus flavus, and Candida albicans with the exception of the palladium(II) complex (4) which showed no activity, while all the compounds showed no activity against Fusarium vasinfectum.

Crystal structure of S-hexyl (E)-3-(2-hy­droxy­benzyl­idene)di­thio­carbazate

The title compound crystallizes with four independent molecules in the asymmetric unit, which have very comparable geometries. In the crystal, molecules are connected in pairs through N—H⋯S hydrogen bonds, forming dimers.

Crystal structure of bis­[μ-S-hexyl 3-(2-oxido­benzyl­idene)di­thio­carbazato-κ4O,N3,S:O]dicopper(II)

The title compound, [Cu2(C14H18N2OS2)2], is a binuclear copper(II) complex of an oxybenzylidenedithiocarbazate ligand. The ligand coordinates in a tridentate manner through N-, S- and O-donor atoms. Each O atom also bridges to a second CuII ion to form the binuclear species. It has a central Cu2O2 rhomboid moiety and a metal-to-metal separation of 2.9923 (6) Å. In the crystal, the binuclear complexes stack along the a axis with all the hexyl chains located side-by-side, forming a hydrophobic region. The complexes are linked via C—H⋯N hydrogen bonds, forming chains along the c-axis direction. One CuII atom has the S atom of a symmetry-related complex located approximately in the apical position at 2.9740 (11) Å. This weak interaction links the chains to form slabs parallel to the ac plane.