Mecheril V. Nandakumar

Cycloaddition reactions of 3-ethoxycarbonyl-2H-cyclohepta[b]furan-2-one with 6,6-dialkyl, cycloalkyl and diaryl pentafulvenes

Abstract Competing [8 + 2] and [4 + 2] modes of additin of 3-ethoxycarbonyl-2H-cyclohepta[b]furan-2-one with dialkyl, cycloalky and diaryl pentafulvenes are described.

Diisopropylaminoisocyanide and DMAD in multiple component reactions (MCRs): novel synthesis of substituted 1-amino-3-pyrrolin-2-ones by reaction with aldehydes and dicarbonyl compounds

The zwitterion generated from diisopropylaminoisocyanide and dimethyl acetylenedicarboxylate (DMAD) reacts with a variety of carbonyl and dicarbonyl compounds affording substituted 1-aminopyrrolin-2-ones.

[8+2] Cycloaddition Reactions of 2H-Cyclohepta[b]furan-2-one with Acyclic 1,3-Dienes: A Facile Route to Novel Bicyclo [5.3.0] ring Systems

Abstract Novel [8+2] cycloaddition reactions of 3-ethoxy carbonyl 2H-cyclohepta[b]furan-2-one with acyclic 1,3-dienes are described. The potential application of this process in the synthesis of modified colchicinoids incorporating bicyclo [5.3.0] ring systems has also been studied.

1,3-Dipolar Cycloaddition Reaction of Nitrile N-Oxides to 6-(2-Phenylethenyl)fulvene

Abstract Dipolar cycloaddition reactions of aryl nitrile oxides to 6-(2-phenylethenyl)fulvene leading to isoxazolines are described.

Cycloaddition reactions of 2-oxo-2H-cyclohepta[b]furan derivatives with dienes and dienophiles

Abstract Cycloaddition reactions of 2-oxo-2H-cyclohepta[b]furan derivatives participating as 8π and 4π components respectively towards different dienes and dienophiles are described. The observed reactivity and periselectivity have been rationalized by AM1 calculations.