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Dive into the research topics where Megan E. Mignemi is active.

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Featured researches published by Megan E. Mignemi.


Journal of Hand Surgery (European Volume) | 2013

Radiographic Outcomes of Volar Locked Plating for Distal Radius Fractures

Megan E. Mignemi; Ian R. Byram; Carmen C. Wolfe; Kang-Hsien Fan; Elizabeth Koehler; John J. Block; Martin I. Jordanov; Jeffry T. Watson; Douglas R. Weikert; Donald H. Lee

PURPOSE To assess the ability of volar locked plating to achieve and maintain normal radiographic parameters for articular stepoff, volar tilt, radial inclination, ulnar variance, and radial height in distal radius fractures. METHODS We performed a retrospective review of 185 distal radius fractures that underwent volar locked plating with a single plate design over a 5-year period. We reviewed radiographs and recorded measurements for volar tilt, radial inclination, ulnar variance, radial height, and articular stepoff. We used logistic regression to determine the association between return to radiographic standard norms and fracture type. RESULTS At the first and final postoperative follow-up visits, we observed articular congruence less than 2 mm in 92% of fractures at both times. Normal volar tilt (11°) was restored in 46% at the first follow-up and 48% at the final one. Radial inclination (22°) was achieved in 44% at the first follow-up and 43% at the final one, and ulnar variance (01 ± 2 mm) was achieved in 53% at the first follow-up and 53% at the final one. In addition, radial height (14 ± 1mm) was restored in 14% at the first follow-up and 12% at the final one. More complex, intra-articular fractures (AO class B and C and Frykman types 3, 4, 7, and 8) were less likely to be restored to normal radiographic parameters. However, because of the small sample size for some fracture types, it was difficult to discover significant associations between fracture type and radiographic outcome. CONCLUSIONS Volar locked plating for distal radius fractures achieved articular stepoff less than 2 mm in most fractures but only restored and maintained normal radiographic measurements for volar tilt, radial inclination, and ulnar variance in 50% of fractures. The ability of volar locked plating to restore and maintain ulnar variance and volar tilt decreased with more complex intra-articular fracture types. TYPE OF STUDY/LEVEL OF EVIDENCE Therapeutic IV.


Journal of The American Academy of Orthopaedic Surgeons | 2013

Fingertip injuries: an update on management.

Donald H. Lee; Megan E. Mignemi; Samuel N. Crosby

Abstract Injuries to the fingertip are common. The goal of treatment is restoration of a painless, functional digit with protective sensation. The amount of soft‐tissue loss, the integrity of the nail bed, and the age and physical demands of the patient should be considered when selecting a treatment method. Some new products are effective for management of injuries to the fingertip. The use of 2‐octylcyanoacrylate for nail bed repair is faster than suture repair, with equivalent results reported. Dermal regeneration template is effective for coverage of digital injuries with exposed tendons or bones that lack peritenon or periosteum. Although fingertip replantation offers better functional results than does revision amputation, replantation is more technically demanding and requires longer recovery time. Complications associated with management of injuries to the fingertip include nail deformities, insensate digits, and painful neuromas.


Journal of Pediatric Orthopaedics | 2014

Hemiepiphysiodesis Implants for Late-onset Tibia Vara: A Comparison of Cost, Surgical Success, and Implant Failure.

Shawn S. Funk; Megan E. Mignemi; Jonathan G. Schoenecker; Steven A. Lovejoy; Gregory A. Mencio; Jeffrey E. Martus

Background: The purpose of this study was to compare hemiepiphysiodesis implants for late-onset tibia vara and to evaluate patient characteristics that may predict surgical failure. Methods: This is a retrospective review of late-onset tibia vara patients treated with temporary hemiepiphysiodesis from 1998 to 2012. Mechanical axis deviation (MAD), mechanical axis angle, mechanical lateral distal femoral angle, and medial proximal tibial angle were measured on standing bone length radiographs. Surgical failure was defined as residual deformity requiring osteotomy, revision surgery, or MAD exceeding 40 mm at the time of final follow-up. Implant failure was recorded. Costs included implants and disposables required for construct placement. Staple constructs included 2 or 3 staples. Plate constructs included the plate, screws, guide wires, and drill bits. Results: A total of 25 patients with 38 temporary lateral proximal tibia hemiepiphysiodeses met the inclusion criteria. The average body mass index (BMI) was 39.1 kg/m2 with an average follow-up of 3.0 years (minimum 1 y). Surgical failure occurred in 57.9% of patients. Greater BMI (P=0.05) and more severe deformity (MAD, mechanical axis angle, and medial proximal tibial angle; P<0.01) predicted higher rates of surgical failure. Younger age predicted higher rates of implant failure (P<0.01). There were no differences in surgical or implant failure between staple and plate systems. Hospital costs of plate constructs (


Journal of Hand Surgery (European Volume) | 2013

Controversies in the Treatment of Nail Bed Injuries

Megan E. Mignemi; Kenneth P. Unruh; Donald H. Lee

781 to


Journal of Pediatric Orthopaedics | 2014

Medial Approach for Drainage of the Obturator Musculature in Children

Travis J. Menge; Heather A. Cole; Megan E. Mignemi; William C. Corn; Jeffrey E. Martus; Steven A. Lovejoy; Christopher M. Stutz; Gregory A. Mencio; Jonathan G. Schoenecker

1244) were 1.5 to 3.5 times greater than the staple constructs (


Journal of Bone and Joint Surgery, American Volume | 2013

Vitamin K-Dependent Coagulopathy in Pediatric Osteomyelitis

Megan E. Mignemi; Neal W. Langdon; Jonathan G. Schoenecker

332 to


Orthopedic Clinics of North America | 2017

Double-Edged Sword: Musculoskeletal Infection Provoked Acute Phase Response in Children

Michael A. Benvenuti; Thomas J. An; Emilie Amaro; Steven A. Lovejoy; Gregory A. Mencio; Jeffrey E. Martus; Megan E. Mignemi; Jonathan G. Schoenecker

498). Conclusions: Greater BMI, more severe deformity, and younger age were predictive of surgical or implant failure. There was no difference in success between implant types, whereas the cost of plate constructs was 1.5 to 3.5 times greater than staples. The rate of surgical failure was high (58%) and consideration should be given to reserving hemiepiphysiodesis for patients with lower BMI and less severe deformity. In our population, if hemiepiphysiodesis was not offered to patients with BMI>35 or MAD>80 mm varus, the surgical failure rate would diminish to 28%. The failure rate outside these parameters would be 88%. Level of Evidence: Level II—Prognostic.


Journal of Pediatric Orthopaedics | 2016

A Novel Classification System Based on Dissemination of Musculoskeletal Infection is Predictive of Hospital Outcomes

Megan E. Mignemi; Michael A. Benvenuti; Thomas J. An; Jeffrey E. Martus; Gregory A. Mencio; Stephen A. Lovejoy; Lawson A. Copley; Derek J. Williams; Isaac P. Thomsen; Jonathan G. Schoenecker

The Review Section of JHS will contain at least 3 clinically relevant articles selected by theeditor to be offered for CME in each issue. For CME credit, the participant must read thearticles in print or online and correctly answer all related questions through an onlineexamination. The questions on the test are designed to make the reader think and willoccasionallyrequirethereadertogobackandscrutinizethearticlefordetails.TheJHSCMEActivityfeeof


Journal of Pediatric Orthopaedics | 2016

Validation and Modification of a Severity of Illness Score for Children With Acute Hematogenous Osteomyelitis

Alexander G. Athey; Megan E. Mignemi; William T. Gheen; Eduardo A. Lindsay; ChanHee Jo; Lawson A. Copley

20.00includestheexamquestions/answersonlyanddoesnotincludeaccesstotheJHSarticlesreferenced.


Jbjs reviews | 2016

Pediatric Musculoskeletal Infection: Hijacking the Acute-Phase Response.

Thomas J. An; Michael A. Benvenuti; Megan E. Mignemi; Isaac P. Thomsen; Jonathan G. Schoenecker

Background: In a recent study designed to determine the anatomic location of infection in children presenting with acute hip pain, fever, and elevated inflammatory markers, we demonstrated the incidence of infection of the musculature surrounding the hip to be greater than twice that of septic arthritis. Importantly, the obturator musculature was infected in >60% of cases. Situated deep in the pelvis, surrounding the obturator foramen, debridement of these muscles and placement of a drain traditionally requires an extensive ilioinguinal or Pfannenstiel approach, placing significant risk to the surrounding neurovascular structures. We hypothesized that the obturator internus and externus could be successfully debrided using a limited medial approach. Methods: An IRB-approved prospective study of children (0 to 18 y) evaluated in the pediatric emergency department by an orthopaedic surgeon to rule out septic hip arthritis at a tertiary care children’s hospital (July 1, 2010 to June 30, 2012) was conducted. Infected obturator musculature was identified and confirmed using magnetic resonance imaging. Cadaveric dissection was performed comparing the ilioinguinal, Pfannenstiel, and proposed minimally invasive medial approach. The proposed approach was utilized to debride and place drains in 7 consecutive patients. Results: Anatomic information gained from magnetic resonance images of patients with abscess within the obturator musculature, and from the results of cadaveric studies, allowed for planning of a novel surgical approach. We found that through the surgical approach used to perform an osteotomy of the ischium (Tonnis) the obturator externus could be debrided through the adductor brevis and the obturator internus could be debrided through the obturator foramen. Using our medial approach, resolution of symptoms in all children who underwent surgical drainage resulted without complication. Conclusions: Our medial approach can safely access the obturator musculature for abscess decompression and drain placement with successful results. Advantages to this approach include: lower risk to neurovascular structures within the pelvis, less soft tissue trauma, and similarity to current techniques used for adductor lengthening, medial reduction of the dislocated hip, and osteotomy of the ischium. Level of Evidence: Level II.

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Jonathan G. Schoenecker

Vanderbilt University Medical Center

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Gregory A. Mencio

Vanderbilt University Medical Center

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Steven A. Lovejoy

Vanderbilt University Medical Center

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Donald H. Lee

Vanderbilt University Medical Center

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Ena Nielsen

Children's Hospital Los Angeles

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