Megan Tran
Princeton University
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Megan Tran.
Journal of Medicinal Chemistry | 2009
Dahui Zhou; Gary Paul Stack; Jennifer R. Lo; Amedeo Arturo Failli; Deborah Ann Evrard; Boyd L. Harrison; Nicole T. Hatzenbuhler; Megan Tran; Susan Christman Croce; Soo Yi; Jeannette Golembieski; Geoffrey Hornby; Margaret Lai; Qian Lin; Lee E. Schechter; Deborah L. Smith; Adam D. Shilling; Christine Huselton; Paul J. Mitchell; Chad E. Beyer; Terrance H. Andree
On the basis of the previously reported clinical candidate, SSA-426 (1), a series of related 2-piperazin-1-ylquinoline derivatives 3-16 were synthesized and evaluated as dual-acting serotonin (5-HT) reuptake inhibitors and 5-HT1A receptor antagonists. In particular, compound 7 exhibits potent functional activities at both the 5-HT transporter and 5-HT1A receptor, good selectivity over the alpha1-adrenergic and dopaminergic receptors, acceptable pharmacokinetic properties, and a favorable in vivo profile.
Archive | 2003
Gary Paul Stack; Megan Tran; Byron Abel Bravo
Archive | 2002
Megan Tran; Gary Paul Stack
Bioorganic & Medicinal Chemistry Letters | 2004
Adam M. Gilbert; Gary Stack; Ramaswamy Nilakantan; Jason Kodah; Megan Tran; Rosemary Scerni; Xiaojie Shi; Deborah L. Smith; Terrance H. Andree
Archive | 2002
Rulin Zhao; Megan Tran; Richard Eric Mewshaw; Gary Paul Stack
Archive | 2002
Megan Tran; Gary P. Stack
Archive | 2002
Gary Paul Stack; Megan Tran; Byron Abel Bravo
Archive | 2002
Megan Tran; Gary Paul Stack
Archive | 2002
Megan Tran; Gary Paul Stack
Archive | 2002
Gary Stack; Adam M. Gilbert; Megan Tran
