Mehmet Hakan Korkmaz

Spindle Cell Carcinoma of the Tongue: A Rare Tumor in an Unusual Location

Spindle cell carcinoma is a rare biphasic tumor consisting of epithelial and mesenchymal components. Presence of this tumor type in the tongue has rarely been reported. Herein, a case of 55-year-old woman who presented with a polypoid lesion at her tongue has been reported. Surgery was performed and pathologic examination revealed a spindle cell carcinoma. We present this rare tumor with an unusual location to contribute in part to the better understanding and awareness of this rare malignancy.

The effects of anterior palatoplasty on floppy eyelid syndrome patients with obstructive sleep apnea

To investigate the effects of anterior palatoplasty on the presence and stage of floppy eyelid syndrome (FES) among patients diagnosed with mild or moderate obstructive sleep apnea (OSA) according to the apnea‐hypopnea index (AHI).

An extremely rare case of thyroid malignancy from the non-Alpine region: Angiosarcoma

Highlights • Thyroid angiosarcoma is a quite rare and aggressive malignancy with poor prognosis.• A patient is presented who died postoperatively due to recurrent hematomas.• Extracapsular invasion and distant metastasis are strong negative prognostic factors.• Treatment is difficult due to local aggression, destruction and high recurrence.• In differential diagnosis for anaplastic carcinoma, angiosarcoma should be kept in mind.

Permanent central diabetes insipidus as a complication of sphenoid sinus mucocele

Although mucocele is a benign lesion, its unavoidable expansions may result in irreversible damages in adjacent organs. In spheno-ethmoid mucoceles which are extremely rare, this condition may cause more severe problems. Central diabetes insipidus, developed secondary to sphenoid sinus mucocele, was detected in a 54-year-old male patient, who underwent endoscopic sinus surgery 2 times due to nasal polyposis. Endoscopic sphenoid mucocele marsupialization was performed to the patient, but despite partial regression in the 1-year follow up, complete recovery was not observed.

Does CPAP treatment affect the voice

BACKGROUND/AIM The aim of this study was to investigate alterations in voice parameters among patients using continuous positive airway pressure (CPAP) for the treatment of obstructive sleep apnea syndrome. MATERIALS AND METHODS Patients with an indication for CPAP treatment without any voice problems and with normal laryngeal findings were included and voice parameters were evaluated before and 1 and 6 months after CPAP. Videolaryngostroboscopic findings, a self-rated scale (Voice Handicap Index-10, VHI-10), perceptual voice quality assessment (GRBAS: grade, roughness, breathiness, asthenia, strain), and acoustic parameters were compared. RESULTS Data from 70 subjects (48 men and 22 women) with a mean age of 44.2 ± 6.0 years were evaluated. When compared with the pre-CPAP treatment period, there was a significant increase in the VHI-10 score after 1 month of treatment and in VHI- 10 and total GRBAS scores, jitter percent (P = 0.01), shimmer percent, noise-to-harmonic ratio, and voice turbulence index after 6 months of treatment. Vague negative effects on voice parameters after the first month of CPAP treatment became more evident after 6 months. CONCLUSION We demonstrated nonsevere alterations in the voice quality of patients under CPAP treatment. Given that CPAP is a long-term treatment it is important to keep these alterations in mind.

DOES NEUTROPHIL TO LYMPHOCYTE RATIO PREDICT HOSPITAL STAY IN APPENDECTOMY PATIENTS

BACKGROUND We aimed to investigate the relationship between the neutrophil to lymphocyte ratio (NLR) and postoperative length of hospital stay. In addition, the impact of radiological and histopathological findings on hospital stay was also evaluated. METHOD This is a retrospective study. One hundred three patients with appendicitis were in-cluded. The diagnosis was confirmed by computed tomography (CT), ultrasonography and histopathological examination. Correlations between the length of hospital stay and age, gender, NLR, c-reactive peptide levels (CRP), the appendix diameter on CT or ultrasonogra-phy, appendix localisation and pathology reports were evaluated. RESULTS The length of hospital stay was not related to age or gender. The length of hospital stay after appendectomy was correlated with appendix diameter on CT and phlegmonous appendicitis, but it was not associated with NLR, CRP levels or the appendix diameter on ultrasonography. CONCLUSION To our knowledge, this is the first comprehensive study to evaluate the associa-tion between NLR levels and the length of hospital stay in patients with acute appendicitis. The NLR was not found to be associated with the length of hospital stay. The appendix di-ameter on CT and appendix pathology reports were correlated with the length of postopera-tive hospital stay in appendectomy patients.

The effect of inlay butterfly cartilage tympanoplasty technique on compliance

Abstract Conclusion: IBCT technique should be preferred owing to its high graft survival rate and ABG gain. While no significant difference was found in middle ear pressures between ears that underwent IBCT and normal ears, compliance values were found to be decreased in patients undergoing IBCT. However, the lack of correlation between ABG gain and compliance values indicated that compliance increase had no effect on post-operative ABG results. Objective: The aim of the present study was to compare tympanometric and audiological parameters in patients undergoing inlay butterfly cartilage tympanoplasty (IBCT) with their normal ears and to determine their difference with normal ear tympanometric parameters. Methods: Overall, 25 patients that underwent an operation between August 2010–May 2014 were included in the present study. In 13 of these patients, the ear that did not undergo operation was normal. 0.5, 1, 2, 4 kHz pure sound average values, tympanometric measurements and compliance values of normal and operated ears were compared. Results: The graft survival rate in patients was found to be 92%. Mean pre-operative air–bone gap (ABG) was 16.4 ± 5.4 in patients, while mean post-operative ABG was 10.9 ± 5.8, with a statistically significant difference (p = 0.001) While there was no significant difference between operated and normal ears of patients in terms of middle ear pressure (0.441), compliance values were significantly higher in normal ears than those in operated ears (0.032). When post-operative ABG gain was compared with compliance values, no significant correlation was found between ABG gain and compliance measurements (r = −0.025 and p = 0.936).

Unilateral nasal pathologies: clinical presentation and management

Bulgular: Bulgular› incelenen 73 hastan›n; 16’s›nda neoplastik, 57’sinde neoplastik olmayan patoloji tespit edildi. Neoplastik olmayan lezyonlara bakt›¤›m›zda; 16 olguda inflamatuar polip, 11 olguda kronik sinüzit, 6 olguda antrokoanal polip, en çok göze çarpan nedenlerdi. Neoplastik grubu ise 2’si malign, 14’ü benign 16 olgu oluflturmaktayd›. Bu olgular; 1 adenokarsinom, 1 adenoid kistik karsinom, 8 inverted papillom, 1 hemanjioendotelyoma, 1 kapiller hemanjiom, 1 fibröz displazi, 1 osteom, 2 pyojenik granülomdan oluflmaktayd›. En s›k gözlenen semptom, tek tarafl› burun t›kan›kl›¤›yd›. Özellikle neoplazm olgular›nda burun kanamas› s›kl›¤› anlaml› olarak artm›flt› (p<0.05).

Glottic airway gain after 'suture arytenoid laterofixation' in bilateral vocal cord paralysis

Abstract Conclusion: This method is an easy, non-expensive, and effective technique in bilateral vocal cord paralysis to improve glottic airway and clinical performance. Objective: To evaluate the effectiveness of ‘suture arytenoid laterofixation’ surgery in bilateral vocal cord paralysis. Materials and methods: A retrospective analysis of patients’ medical history undergoing ‘suture arytenoid laterofixation’ surgery for bilateral vocal cord paralysis. This technique was applied under general anesthesia with both microlaryngoscopy and video-monitoring. Two 16 g needles and one 1/0 nylon thread were used for the procedure with 1 cm skin incision; no tracheotomy or tissue excision was required. Pre–post-operative photographs of the glottic region were taken from the endoscopic records, and the areas of rima glottis openings were calculated with the Image-J programme. Results: Forty-seven patients were analyzed. The mean pre–post-operative rima glottis areas were 1.11 ± 0.56 and 2.24 ± 0.93 mm2, respectively (p < 0.001). Five patients with previous tracheotomy were decannulated within a few days after the operation. In three patients, mild complications developed in the early post-operative period (two laryngeal edemas, one submucosal hematoma). Tracheotomy was performed to only one pregnant patient in the post-operative first day. None of the patients had granulation formation or synechia.

Comparison of tone burst versus logon stimulation for vestibular evoked myogenic potentials

The following study has been carried out to compare the effectiveness of logon and tone burst acoustic stimulation to elicit vestibular evoked myogenic potential (VEMP) responses. The methods and the subjects include 31 healthy adult volunteers (62 ears) who were enrolled in this study. Two different acoustic stimuli, logon (L-VEMP) and tone burst (T-VEMP), were used to elicit VEMP responses in each subject. Bilateral recordings with simultaneous binaural acoustic stimulations were used during VEMP recordings. During the recording period, the subjects were in supine position with their head elevated. The results observed were that the response rate of p1n1 wave was 91.9% for L-VEMP and 88.7% for T-VEMP. The response rate of n2p2 wave was 80.6% for L-VEMP, and 75.8% for T-VEMP. There were no significant differences between the two groups with respect to the latencies of p1, n1, n2 and p2, p1n1 and n2p2 interval, and p1n1 and n2p2 amplitude. The conclusion was that there was no difference between logon and tone burst stimulation with respect to VEMP response rates and VEMP parameters. Therefore, they are not superior to each other.