Mehmet Inci

Toxic effects of formaldehyde on the urinary system.

Formaldehyde is a chemical substance with a pungent odor that is highly soluble in water and occurs naturally in organisms. Formaldehyde, when taken into organisms, is metabolized into formic acid in the liver and erythrocytes and is then excreted, either with the urine and feces or via the respiratory system. Form-aldehyde is widely used in the industrial and medical fields, and employees in these sectors are frequently exposed to it. Anatomists and medical students are affected by formaldehyde gas during dissection lessons. Because full protection from formaldehyde is impossible for employees in industrial plants using this chemical and for workers in laboratory conditions, several measures can be implemented to prevent and/or reduce the toxic effects of formaldehyde. In this review, we aimed to identify the toxic effects of formaldehyde on the urinary system.

Caffeic acid phenethyl ester (CAPE) protects against acute urogenital injury following pneumoperitoneum in the rat

Abstract Purpose: Our aim is to determine the biochemical and histologic changes induced in the kidneys, testis and prostate on possible ischemia and reperfusion (I/R) injury caused by pneumoperitoneum (PNP) in a rat model and to evaluate the ability of protective effects of caffeic acid phenethyl ester (CAPE). Methods: Twenty-eight adult male Wistar albino rats were randomly divided to one of three treatment groups, with seven animals in each group. Sham, laparoscopy (L), and laparoscopy plus CAPE (L + C) group were subjected to 60 min of PNP with 15 mmHg one hour before the desufflation period. Total oxidant status (TOS) and total antioxidant status (TAS) levels were determined in kidney, testis, and prostate. Kidney and testis tissues were removed to obtain a histologic score. Also, Johnsen scoring system was used for testicular tissue analysis. Results: L group had significantly higher TOS and lower TAS levels on kidney and testis compared to the other groups. In prostate biochemical analysis, there was not any difference between groups. No difference was found between groups according to kidney and testis tissues’ histologic evaluation. In evaluation of Johnsen scoring, L group showed significant lower score compared to the other two groups. Conclusions: Increased intraabdominal pressure (IAP) had an oxidative effect on kidney and testis but not on prostate in rats. Moreover, it could affect the testicular Johnsen score. All these adverse effects of IAP on both kidney and testis could be prevented by CAPE administration.

Heterotopic ossification of the spermatic cord

Heterotopic ossification is the most frequenttype of connective tissue metaplasia. We reporta rare case with bone formation in thespermatic cord.

Üriner sistem taşlarında iki senelik şok dalgası ile taş kırma tedavisi sonuçları

Objectives: To evaluate the results of the extracorporeal electro shockwave lithotripsy (SWL) therapy in urinary system stone disease and to investigate the factors that affects the success. Results: In our study, of 101 patients, 68 (67.3%) male and 33 (32.7%) female patients, who had complaints with urolithiasis, were analyzed. The success rates when com- pare the localization of the stone formation independent of stone size were found 52.4%, 68%, 100% and 76.5% at lower, middle, upper calices and pelvis of kidney, re- spectively. In our study, the success rate according to stone size was 73.7%, 75%, 25% and 50% in lower than 100 mm2, 100-200 mm 2 , 200-300 mm 2 and higher than 300 mm 2 in diameter, respectively. For ureteral localiza- tions, the success rate was 75%, 76.9% and 71.4% in upper, middle and lower ureter, respectively. Conclusions: In SWL therapy, success depends on size and localization of the stone. Our success rate was al- tered in terms of stone size and localization similar to pre- vious reports.