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Dive into the research topics where Melanie J. Loots is active.

Publication


Featured researches published by Melanie J. Loots.


Journal of the American Chemical Society | 1980

Nickel-catalyzed conjugate addition of alkenylzirconium species to .alpha.,.beta.-unsaturated ketones

Jeffrey Schwartz; Melanie J. Loots; Hiroshi Kosugi


Journal of the American Chemical Society | 1982

Kinetic determination of transition-metal-alkyl bond dissociation energies: Application to organocobalt compounds related to B12 coenzymes

Tsung Ting Tsou; Melanie J. Loots; Jack Halpern


Journal of Medicinal Chemistry | 1988

(Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme (ACE). 1. Discovery of (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline, a novel orally active inhibitor of ACE

Donald S. Karanewsky; Michael C. Badia; David W. Cushman; Jack M. DeForrest; Tamara Dejneka; Melanie J. Loots; Maria G. Perri; Edward W. Petrillo; James R. Powell


Journal of the American Chemical Society | 1977

Nickel-catalyzed conjugate addition of zirconium alkenyls to .alpha.,.beta.-unsaturated ketones

Melanie J. Loots; Jeffrey Schwartz


Archive | 1991

3,3,3-trifluoro-2-mercaptomethyl-N-tetrazolyl substituted propanamides and method of using same

Norma G. Delaney; George C. Rovnyak; Melanie J. Loots


Tetrahedron Letters | 1977

Transmetalation. II. A convenient preparation of vinylic copper(I) species from acetylenes via organozirconium intermediates

Masaaki Yoshifuji; Melanie J. Loots; Jeffrey Schwartz


Journal of Medicinal Chemistry | 1990

(Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme. 2. Terminal amino acid analogues of (S)-1-[6-amino-2 [[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline.

Donald S. Karanewsky; Michael Badia; David W. Cushman; Jack M. DeForrest; Tamara Dejneka; Ving G. Lee; Melanie J. Loots; Edward W. Petrillo


Archive | 1993

Trifluoromethyl mercaptan and mercaptoacyl derivatives and method of using same

Norma G. Delaney; George C. Rovnyak; Melanie J. Loots


Archive | 1984

Bicycloheptane substituted ethers

Melanie J. Loots; Steven E. Hall; Peter W. Sprague


Archive | 1987

Substituted aminoalkanoylaminoalkyl phosphonate angiotensin converting enzyme inhibitors

Melanie J. Loots; Donald S. Karanewsky

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Donald S. Karanewsky

Genomics Institute of the Novartis Research Foundation

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