Melinda K. Harman

Knee motions during maximum flexion in fixed and mobile-bearing arthroplasties.

Full flexion is a critical performance requirement for patients in Asia and the Middle East, and increasingly for patients in Europe and North America who have total knee arthroplasty. There has been considerable work characterizing maximum flexion in terms of clinical, surgical, and preoperative factors, but less in vivo experimental work after rehabilitation. The purpose of the current investigation was to determine whether anteroposterior tibiofemoral translation influenced maximum weightbearing knee flexion in patients with good or excellent clinical and functional outcomes. One hundred twenty-one knees in 93 subjects, including 16 different articular surface designs, were studied using fluoroscopy and shape matching to determine knee kinematics in a weightbearing deep flexion activity. A relatively posterior position of the femur on the tibia was significantly correlated with greater maximum knee flexion. Posterior-stabilized arthroplasties had significantly more posterior femoral position and maximum flexion than posterior cruciate-retaining fixed-bearing arthroplasties, which had more posterior femoral position and greater maximum flexion than mobile-bearing arthroplasties. Posterior bone-implant impingement was observed in 28% of knees. Tibiofemoral motions influence the mechanics of weightbearing deep flexion in well-functioning knee arthroplasties.

Wear analysis of a retrieved hip implant with titanium nitride coating

There is increasing interest in using surface modification technology to improve the wear properties of titanium alloy and limit articular surface wear of metal and polyethylene components. This report details the in vivo wear performance of titanium nitride coating on a retrieved hip implant obtained postmortem from a low demand patient 1 year after total hip arthroplasty. Analysis of the well-functioning implant revealed that wear debris can originate from a titanium nitride coated femoral head, as delaminated surface asperities, and manifest as adhesive wear on the articular surface. The wear observed on this implant indicates that rigorous testing and evaluation of titanium nitride coating technology should be conducted prior to widespread use on total joint implants.

Polyethylene damage and knee kinematics after total knee arthroplasty.

This study characterizes the relationship between in vivo knee kinematics and polyethylene damage by combining fluoroscopic analysis of tibiofemoral contact during dynamic activities and implant retrieval analysis in the same patients. Six patients (eight knees) underwent posterior cruciate ligament-retaining total knee arthroplasty. All patients participated in fluoroscopic analysis during a stair-rise and descent activity and treadmill gait an average of 18 months after arthroplasty, and articular contact was measured. Subsequently, all polyethylene tibial inserts were retrieved after an average of 26 months in vivo function: three at autopsy and five at revision. There was a statistically significant correlation between the damage location on the retrieved inserts and the articular contact location measured fluoroscopically during the activities. The femoral contact and polyethylene damage occurred predominantly on the posterior half of the tibial articular surface, and the damage pattern was largest in the compartment with the greatest range of in vivo femoral contact for each patient. This study showed that in vivo fluoroscopic analysis can predict the damage location on the polyethylene articular surface.

Wear patterns on tibial plateaus from varus and valgus osteoarthritic knees.

The size and location of articular cartilage wear was assessed on 106 varus and 37 valgus osteoarthritic tibial plateaus resected during total knee arthroplasty. Anterior cruciate ligament integrity was assessed intraoperatively, and calibrated digital images were used to measure the wear patterns. Complete anterior cruciate ligament deficiency was seen in 25% of the varus and 24% of the valgus knees. Wear patterns on anterior cruciate ligament intact and attenuated varus tibial plateaus occurred in the middle to anterior aspect of the medial plateau. Anterior cruciate ligament deficient varus plateaus had significantly larger wear areas located more posterior on the medial plateau. In contrast, anterior cruciate ligament intact and deficient valgus tibial plateaus had wear located posterior to the center of the lateral plateau. Anterior cruciate ligament integrity is a discrete feature of advanced osteoarthritis that strongly influences the articular wear patterns. The anterior cruciate ligament deficient wear patterns show a wear mechanism that is consistent with the posterior femoral subluxation and posterior tibiofemoral contact observed after acute anterior cruciate ligament rupture. These observations provide insight into the altered knee mechanics that exist in osteoarthritic knees and the resulting mechanical factors that contribute to degenerative changes.

Making Sense of Knee Arthroplasty Kinematics: News You Can Use

Many groups are reporting results of in vivo studies of knee replacement motions. Despite this growing abundance of data, it may be difficult for the practicing orthopaedist to glean usable information from these highly technical studies. This paper summarizes key study findings related to implant design and surgical strategy. A number of important issues are explored: surgical technique, range of motion, patterns of knee motion, polyethylene wear, and functional knee strength.⇓,⇓ Fig 1: Knee prostheses with a flat tibial insert and a femoral component with a large distal radius can exhibit posterior femoral translation with knee flexion1. However, achieving this pattern of motion appears to depend on surgical technique. Many knee replacements with the same or similar designs exhibit different patterns of motion2-9. (Reprinted, with permission, from: Nozaki H, Banks SA, Suguro T, Hodge WA. Observations of femoral rollback in cruciate-retaining knee arthroplasty. Clin Orthop. 2002;404:310.) Fig 2: Figs. 2-A and 2-B Patterns of anteroposterior translations during a stair-climbing activity in two groups of patients who were operated on by two different surgeons using the same design of knee arthroplasty1. There were no differences between groups in terms of clinical or demographic factors, preoperative disease, implant alignment, or postoperative clinical and functional outcomes. Each line represents the group mean, plus or minus one standard deviation. The open circles indicate flexion ranges at which there were significant differences between the two groups. The anterior-posterior midpoint of the tibial plateau is 0 on the vertical axis. Fig. 2-A Medial tibiofemoral contact was significantly more posterior in Group 1 throughout most of the flexion arc. Fig. 2-B Lateral tibiofemoral contact was significantly more posterior in Group 1 from 50° to 90° of flexion. (Reprinted, with permission, from: Nozaki H, Banks SA, Suguro T, Hodge WA. Observations …

Initial stability of uncemented hip stems: an in-vitro protocol to measure torsional interface motion

The difficulty in quantitatively assessing the inherent variables of surgical stem insertion and interfemur differences continues to be a problem in experimental methodologies which assess hip stem stability. An in-vitro torsional stability protocol was developed which limited the mechanical testing variability and provided a reproducible micromotion measurement of an uncemented stem in synthetic composite femurs. Using a controlled mechanical stem insertion resulted in less interfemur variability within each group with the coefficient of variation being reduced from 35% overall to less than 20%. Femurs with shallow stem insertion depths had significantly larger micromotion than femurs having deep stem insertion depths. The sensitivity of the experimental protocol and the synthetic composite femurs to the varied functional behaviour of three different stem designs was demonstrated. The stem with a hollowed anterior-to-posterior proximal section experienced significantly more motion than the two stems with full proximal sections, reinforcing the need for proximal contact to ensure minimal micromotion in torsional loading.

Comparison of polyethylene tibial insert damage from in vivo function and in vitro wear simulation.

Function and wear of total knee arthroplasties were compared by analysis of damage patterns on polyethylene tibial inserts retrieved from patients (Group R) with inserts obtained after in vitro force‐controlled knee joint wear simulation. Two simulator input profiles were evaluated, including standard walking (Group W), and combined walking and stair descent (Group W + S), simulating varied activities and a more severe physiological environment. Damage regions on all inserts were quantitatively assessed. On average, inserts in all groups had internally rotated damage patterns and the greatest articular deformation in the lateral compartment. These patterns were more pronounced in Group W + S compared to Group W. Deformation rates of simulated inserts were analogous to about six years of physiologic function. However, both groups of simulated inserts generally underestimated the magnitude of damage area and extent observed on retrieved inserts, consistent with differences in the simulators tibiofemoral contact mechanics and those known to occur in patients during functional activities. Modification of simulator inputs, such as the increased anteroposterior excursion and more severe loading conditions in Group W + S, can generate greater wear volume, larger damage areas, and increased surface deformation rates compared to standard inputs.

Effect of stair descent loading on ultra-high molecular weight polyethylene wear in a force-controlled knee simulator

Abstract A loading protocol approximating forces, torques and motions at the knee during stair descent was developed from previously published data for input into a force-controlled knee simulator. A set of total knee replacements (TKRs) was subjected to standard walking cycles and stair descent cycles at a ratio of 70:1 for 5 million cycles. Another set of implants with similar articular geometry and the same ultra-high molecular weight polyethylene (UHMWPE) resin (GUR 415), sterilization and packaging was tested with standard walking cycles only. Implant kinematics, gravimetric wear and surface roughness of the UHMWPE inserts were analysed for both sets of implants. Contact stresses were calculated for both loading protocols using a Hertzian line contact model. Significantly greater weight loss (p < 0.05) and more severe surface damage of UHMWPE inserts resulted with the walking + stair descent loading protocol compared to walking cycles only. Anterior-posterior (AP) tibiofemoral contact point displacements were lower during stair descent than walking, but not significantly different (p = 0.05). Contact stresses were significantly higher during stair descent than walking, owing to higher axial loads and the smaller radius of curvature of the femoral components at higher flexion angles. High contact stresses on UHMWPE components are likely to accelerate the fatigue of the material, resulting in more severe wear, similar to what is observed in retrieved implants. Thus the inclusion of loading protocols for activities of daily living in addition to walking is warranted for more realistic in vitro testing of TKRs.

In vitro and finite element analysis of glenoid bone/baseplate interaction in the reverse shoulder design

We developed biomechanical and finite element models, using high-strength polyurethane foam blocks, to represent the glenoid bone/baseplate junction to determine if increasing the distance between the glenoid bone and the center of rotation of the glenosphere increases baseplate motion during static loading in the reverse shoulder design. Although there was a general trend toward increased baseplate motion with increasing distance from the glenoid to the center of rotation, in vitro mechanical testing revealed no significant difference between the 7 glenosphere types tested, with average baseplate motion during 1000 load cycles ranging from 90 mum to 120 mum. Results from the finite element analysis strongly correlated with the in vitro mechanical testing. The magnitude of baseplate motion occurring in a modeled representation of bone under simulated physiologic loading conditions was similar for the 7 reverse shoulder glenoid components tested in this study.

Prosthesis alignment affects axial rotation motion after total knee replacement: a prospective in vivo

BackgroundClinical consequences of alignment errors in total knee replacement (TKR) have led to the rigorous evaluation of surgical alignment techniques. Rotational alignment in the transverse plane has proven particularly problematic, with errors due to component malalignment relative to bone anatomic landmarks and an overall mismatch between the femoral and tibial components’ relative positions. Ranges of nominal rotational alignment are not well defined, especially for the tibial component and for relative rotational mismatch, and some studies advocate the use of mobile-bearing TKR to accommodate the resulting small rotation errors. However, the relationships between prosthesis rotational alignment and mobile-bearing polyethylene insert motion are poorly understood. This prospective, in vivo study evaluates whether component malalignment and mismatch affect axial rotation motions during passive knee flexion after TKR.MethodsEighty patients were implanted with mobile-bearing TKR. Rotational alignment of the femoral and tibial components was measured from postoperative CT scans. All TKR were categorized into nominal or outlier groups based on defined norms for surgical rotational alignment relative to bone anatomic landmarks and relative rotational mismatch between the femoral and tibial components. Axial rotation motion of the femoral, tibial and polyethylene bearing components was measured from fluoroscopic images acquired during passive knee flexion.ResultsAxial rotation motion was generally accomplished in two phases, dominated by polyethylene bearing rotation on the tibial component in early to mid-flexion and then femoral component rotation on the polyethylene articular surface in later flexion. Opposite rotations of the femur-bearing and bearing-baseplate articulations were evident at flexion greater than 80°. Knees with outlier alignment had lower magnitudes of axial rotation and distinct transitions from external to internal rotation during mid-flexion. Knees with femoral-tibial rotational mismatch had significantly lower total axial rotation compared to knees with nominal alignment.ConclusionsMaintaining relative rotational mismatch within ±5° during TKR provided for controlled knee axial rotation during flexion. TKR with rotational alignment outside of defined surgical norms, with either positive or negative mismatch, experienced measurable kinematic differences and presented different patterns of axial rotation motions during passive knee flexion compared to TKR with nominal mismatch. These findings support previous studies linking prosthesis rotational alignment with inferior clinical and functional outcomes.Trial RegistrationClinical Trials NCT01022099