Melissa Nyendak

Using Genomics to Get Rid of Pests

Researchers use a genomic approach to screen for new insecticides to prevent vector-borne disease.

Just a Spoonful of Drug Makes Diversity Go Down

A single dose of clindamycin alters intestinal microbial density in mice and makes them susceptible to Clostridium difficile infections.

A Change of Heart

Low-grade as well as high-grade bacteremia can cause infection of the heart valves.

Molecular sleuthing: Linking leprosy and armadillos

Investigators use molecular epidemiology to link leprosy with armadillo exposure, suggesting a new zoonotic mode of transmission.

HIV Under Cover

HIV replication by cell-to-cell spread enables the virus to evade destruction by antiretroviral drugs without developing drug-resistance mutations.

Preventing HIV Transmission: Early Therapy Is Key

Early combination antiretroviral drug therapy reduces virus transmission to the uninfected partner in HIV serodiscordant couples.

Delving Deeper into the Persistent Mysteries of Tuberculosis

A study using deep sequencing to characterize transposon libraries demonstrates that cholesterol catabolism genes are essential for growth of Mycobacterium tuberculosis.

The Skeleton Key for Intracellular Pathogens: Nanoparticles and Pulmonary Vaccination

A nanoparticle-linked antigen induces cytotoxic T cell responses and protective immunity against influenza in mice.