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PLOS Medicine | 2005

Micronutrient Sprinkles to Control Childhood Anaemia

Stanley Zlotkin; Claudia Schauer; Anna Christofides; Waseem Sharieff; Melody Tondeur; S. M. Ziauddin Hyder

Over 750 million children have iron-deficiency anemia. A simple powdered sachet may be the key to addressing this global problem


PLOS Medicine | 2012

The Double Burden of Obesity and Malnutrition in a Protracted Emergency Setting: A Cross-Sectional Study of Western Sahara Refugees

Carlos Grijalva-Eternod; Jonathan C. K. Wells; Mario Cortina-Borja; Nuria Salse-Ubach; Melody Tondeur; Carmen Dolan; Chafik Meziani; Caroline Wilkinson; Paul Spiegel; Andrew J. Seal

Surveying women and children from refugee camps in Algeria, Carlos Grijalva-Eternod and colleagues find high rates of obesity among women as well as many undernourished children, and that almost a quarter of households are affected by both undernutrition and obesity.


Food and Nutrition Bulletin | 2007

Effect of daily versus once-weekly home fortification with micronutrient Sprinkles on hemoglobin and iron status among young children in rural Bangladesh.

S. M. Ziauddin Hyder; Farhana Haseen; Mizanur Rahman; Melody Tondeur; Stanley Zlotkin

Background The effectiveness of commonly suggested public health interventions to control childhood iron- deficiency anemia has been low. Objective To determine whether iron provided in Sprinkles daily or in a higher dose once weekly affected hemoglobin, serum ferritin levels, and serum transferrin receptor levels, and to determine whether there were dif- ferences in the effects of the two regimens. Methods In this cluster-randomized, community- based trial conducted in rural areas of Bangladesh, 136 children aged 12 to 24 months with mild to moderate anemia (hemoglobin 70–109 g/L) were randomly allo- cated to receive Sprinkles daily (12.5 mg of elemental iron, n = 79) or once weekly (30 mg of elemental iron, n = 73) for 8 weeks. Hemoglobin, serum ferritin, and serum transferrin receptor were assessed at the start and end of the intervention. Results In both groups, there were significant increases in hemoglobin and serum ferritin and a significant decrease in serum transferrin receptor (p < .01). There were no significant differences between the groups in the increases in hemoglobin (16.1 ± 13.2 g/L for the group receiving Sprinkles daily and 12.3 ± 13.3 g/L for the group receiving Sprinkles once weekly) and serum ferritin (10.6 and 5.7 μg/L, respectively). The decrease in serum transferrin receptor also did not significantly differ between the groups (median, −2.5 and −1. 8 mg/L, respectively). The prevalence rates of iron-deficiency anemia, depleted iron stores, and tissue iron deficiency decreased significantly within each group (p < .01), with no significant differences between the groups. Conclusions Home fortification of complementary foods with Sprinkles given either daily or once weekly improved iron-deficiency anemia and iron status among young children.


Food and Nutrition Bulletin | 2013

Operational Guidance on the Use of Special Nutritional Products in Refugee Populations

Sarah Style; Melody Tondeur; Caroline Wilkinson; Allison Oman; Paul Spiegel; Ismail A. R. Kassim; Carlos Grijalva-Eternod; Carmel Dolan; Andrew Seal

Background Stunting, acute malnutrition, and micronutrient malnutrition are persistent public health problems in refugee populations worldwide. In recent years there has been an increase in the availability and use of special nutritional products in emergency and development contexts to help address inadequate nutrient intakes from low-diversity diets. The availability of new special nutritional products, and the decision by the United Nations High Commissioner for Refugees (UNHCR) to use blanket supplementary feeding programs to prevent stunting and anemia, raised new challenges for designing, monitoring, and evaluating nutritional programs. Objective To develop an Operational Guidance on the use of special nutritional products for the prevention of micronutrient malnutrition, stunting, and acute malnutrition in refugee populations. Methods A literature review and a series of consultations with technical experts, operational organizations, and field staff were performed over a period of 2 years. The Operational Guidance was finalized and released in December 2011. Results The Operational Guidance describes six stages for defining nutritional problems and identifying possible solutions; assessing and managing risks; testing acceptability and adherence, program design and implementation; and monitoring and evaluation. Key performance indicators are defined and a working nomenclature for new special nutritional products is described. Conclusions The UNHCR Operational Guidance has filled an important gap in helping field staff deal with the opportunities and challenges of preventing under-nutrition through the use of new products in blanket supplementary feeding programs. The need for further integration of guidance on selective feeding programs is discussed.


PLOS ONE | 2017

Assessment of the effectiveness of a small quantity lipid-based nutrient supplement on reducing anaemia and stunting in refugee populations in the Horn of Africa: Secondary data analysis

Sarah Style; Melody Tondeur; Carlos Grijalva-Eternod; Josephine Pringle; Ismail A. R. Kassim; Caroline Wilkinson; Allison Oman; Carmel Dolan; Paul Spiegel; Andrew Seal

Stunting and micronutrient malnutrition are persistent public health problems in refugee populations. UNHCR and its partner organisations implement blanket supplementary feeding programmes using a range of special nutritional products as one approach to address these issues. The evidence base for the efficacy and effectiveness of a small quantity lipid-based nutrient supplement, Nutributter®, in reducing stunting and anaemia is limited. Secondary data analysis was used to assess the effectiveness of Nutributter® distribution on anaemia and stunting in children aged 6–23 months (programme target group) and 6–59 months (the standard age group sampled in routine nutrition surveys). Analysis was conducted using routine pre and post-intervention cross-sectional nutrition survey data collected between 2008–2011 in five refugee camps in Kenya and Djibouti. Changes in total anaemia (Haemoglobin<110g/L), anaemia categories (mild, moderate and severe), and stunting (height-for-age z-score <-2) were explored using available data on the Nutributter® programme and contextual factors. A significant reduction in the prevalence of anaemia in children aged 6–23 months and 6–59 months was seen in four of five, and in all five camps, respectively (p<0.05). Reductions ranged from 12.4 to 23.0, and 18.3 to 29.3 percentage points in each age group. Improvements were largely due to reductions in moderate and severe anaemia and occurred where the prevalence of acute malnutrition was stable or increasing. No change in stunting was observed in four of five camps. The replicability of findings across five sites strongly suggests that Nutributter® distribution was associated with a reduction in anaemia, but not stunting, among refugee children in the Horn of Africa. Benefits were not restricted to the 6–23 month target group targeted by the nutrition programme. However, even following this intervention anaemia remained a serious public health problem and additional work to define and evaluate an effective intervention package is warranted.


The American Journal of Clinical Nutrition | 2004

Determination of iron absorption from intrinsically labeled microencapsulated ferrous fumarate (sprinkles) in infants with different iron and hematologic status by using a dual-stable-isotope method

Melody Tondeur; Claudia Schauer; Anna Christofides; Kwaku Poku Asante; Samuel Newton; Robert E. Serfass; Stanley Zlotkin


PLOS MED , 2 (1) , Article e1. (2005) | 2005

Micronutrient sprinkles to control childhood anaemia - A simple powdered sachet may be the key to addressing a global problem

Stanley Zlotkin; Claudia Schauer; Anna Christofides; Waseem Sharieff; Melody Tondeur; Smz Hyder


The American Journal of Clinical Nutrition | 2006

Physiologic mechanisms can predict hematologic responses to iron supplements in growing children: a computer simulation model

Waseem Sharieff; Stanley Zlotkin; Melody Tondeur; Brian M. Feldman; George Tomlinson


Public Health Nutrition | 2016

Rapid acceptability and adherence testing of a lipid-based nutrient supplement and a micronutrient powder among refugee children and pregnant and lactating women in Algeria

Melody Tondeur; U Núria Salse; Caroline Wilkinson; Paul Spiegel; Andrew Seal


Field Exchange 57 | 2018

Monitoring and evaluation of programmes in unstable populations: Experiences with the UNHCR Global SENS Database

Melody Tondeur; Caroline Wilkinson; Valérie Gatchell; Tanya Khara; Mark Myatt

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Caroline Wilkinson

United Nations High Commissioner for Refugees

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Paul Spiegel

United Nations High Commissioner for Refugees

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Andrew Seal

University College London

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Allison Oman

United Nations High Commissioner for Refugees

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Ismail A. R. Kassim

United Nations High Commissioner for Refugees

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