Michael D. Edge
Imperial Chemical Industries
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Publication
Featured researches published by Michael D. Edge.
Tetrahedron Letters | 1989
Anne M. Alves; David Holland; Michael D. Edge
Abstract Protected D(+)-biotin methylesters 3 were reduced to the corresponding alcohols 4 and phosphitylated with chloromethoxymorpholinophosphine. The resulting phosphoramidites 5 were used on a commercial DNA synthesiser to biotinylate synthetic DNA.
Analytical Biochemistry | 1983
Clive R. Newton; April R. Greene; Gillian R. Heathcliffe; Thomas C. Atkinson; David Holland; Alexander F. Markham; Michael D. Edge
The superiority of buffer systems containing formamide for the ion-exchange high-performance liquid chromatographic separation of oligodeoxyribonucleotide mixtures generated in solid-phase syntheses is illustrated. The resolutions achieved are compared to those achieved with the same mixtures in other eluting solvents. The use of formamide systems is recommended for oligodeoxyribonucleotide purification in general and is particularly valuable where the oligonucleotide of interest is highly self-complementary and/or rich in deoxyguanosine residues.
Nature | 1981
Michael D. Edge; April R. Greene; Gillian R. Heathcliffe; Peter Anthony Meacock; Wolfgang Schuch; Denis B. Scanlon; Thomas C. Atkinson; Clive R. Newton; Alexander Fred Markham
Nucleic Acids Research | 1993
Clive R. Newton; David Holland; L.E. Heptinstall; I. Hodgson; Michael D. Edge; Alexander F. Markham; M.J. McLean
Nucleic Acids Research | 1980
M.J. Gait; M. Singh; R.C. Sheppard; Michael D. Edge; A.R. Greene; G.R. Heathcliffe; T.C. Atkinson; Clive R. Newton; Alexander F. Markham
Nucleic Acids Research | 1983
Michael D. Edge; A.R. Greene; G.R. Heathcliffe; V. E. Moore; N.J. Faulkner; R. Camble; N.N. Petter; P. Trueman; Wolfgang Schuch; J. Hennam; T.C. Atkinson; Clive R. Newton; A.F. Markham
Nucleic Acids Research | 1980
Alexander F. Markham; Michael D. Edge; T.C. Atkinson; A.R. Greene; G.R. Heathcliffe; Clive R. Newton; D. Scanlon
Nucleic Acids Research | 1990
C.J. Baker; David Holland; Michael D. Edge; Alan Colman
Nucleic Acids Research | 1993
Richard D. Morgan; Michael D. Edge; Alan Colman
Archive | 1982
Keith Thurston Atherton; Maeyer Edward De; Michael D. Edge; Alexander Fred Markham; Peter Anthony Meacock; John David Windass
