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Dive into the research topics where Michael F. Tenholder is active.

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Featured researches published by Michael F. Tenholder.


The American Journal of Medicine | 1993

Verapamil intoxication: A literature review of overdoses and discussion of therapeutic options

Carolyn A. Hofer; James K. Smith; Michael F. Tenholder

Calcium channel antagonists can be quite toxic. In the management of poisoning, early recognition is critical. Calcium channel antagonists are frequently prescribed, and the potential for serious morbidity and mortality with overdosage is significant. Ingestion of these agents should be suspected in any patient who presents in an overdose situation with unexplained hypotension and conduction abnormalities. The potential for toxicity should be noted in patients with underlying hepatic or renal dysfunction who are receiving therapeutic doses. Because there is no specific antidote, decontamination of the gastrointestinal tract is crucial. Intravenous calcium should be administered to symptomatic patients because it is relatively innocuous and may be beneficial. Volume expansion should be the initial approach to hypotension unrelated to bradycardia. Patients who have had a verapamil overdose should be observed in intensive care units where Swan-Ganz catheterization and ventricular pacing are routinely available. The choice of sympathomimetic agents for treatment remains controversial. According to the published literature, isoproterenol, epinephrine, and norepinephrine may be more effective in improving bradycardia and the resultant hypotension than dopamine. However, none of these agents is universally effective. A more logical approach may be to improve cardiac output with agents like amrinone. Bay K 8644 and 4-aminopyridine show promise as potential antidotes but at present are still experimental.


American Journal of Infection Control | 1993

Tuberculosis surveillance: Lessons from a cluster of skin test conversions

Eunice H. Steimke; Michael F. Tenholder; Malkanthie I. Mccormick; J. Peter Rissing

Mycobacterium tuberculosis has reemerged as a significant public health problem. Elderly persons, especially those in long-term care facilities, are among those at high risk for infection with M. tuberculosis. Frequently, their symptoms are not clearly indicative of M. tuberculosis, and the diagnosis may thus be missed. We discuss the investigation of a cluster of skin test conversions on one locked unit in our long-term care facility. During the epidemiologic investigation, four of 25 patients who had previously had negative results of purified protein derivative testing (16%) and eight of 95 employees (11%) had skin test conversions. Despite a comprehensive, costly evaluation, the index case was not found. We identified weaknesses in our employee and patient M. tuberculosis surveillance programs. Employee baseline purified protein derivative testing data were inadequate. Annual skin tests for employees with previously negative results were not mandatory. There was no mechanism in place to encourage compliance. We developed a plan to educate personnel about the reemergence of M. tuberculosis, signs and symptoms in elderly patients, and the placement and interpretation of purified protein derivative skin tests. Documentation of purified protein derivative surveillance of both patients and employees was computerized. The number of inpatient and outpatient negative-pressure rooms was increased. Appropriate personal protective equipment was made available for use in high-risk situations.


Chest | 1992

Invasive Aspergillus niger with fatal pulmonary oxalosis in chronic obstructive pulmonary disease

Erich A. Kimmerling; Joseph A. Fedrick; Michael F. Tenholder


Chest | 1992

A model for conversion from small volume nebulizer to metered dose inhaler aerosol therapy.

Michael F. Tenholder; Martin J. Bryson; Warren L. Whitlock


Chest | 1993

Bronchogenic carcinoma in patients seropositive for human immunodeficiency virus.

Michael F. Tenholder; Harold D. Jackson


Chest | 1994

Analysis of the Inspiratory Flow-Volume Curve: Should it Always Precede the Forced Expiratory Maneuver?

Frank W. Ewald; Michael F. Tenholder; Rita F. Waller


Chest | 1994

Left Upper Lobe Mass and Diffuse Reticular-Nodular Infiltrate

Harold D. Jackson; Kenneth J. Carney; Mark A. Knautz; Michael F. Tenholder


Chest | 1992

Complex Cryptococcal Empyema

Michael F. Tenholder; Frank W. Ewald; Nayereh K. Khankhanian; John H. Crosby


Chest | 1993

THE PENDULUM AND THE ARTERIAL LINE

Michael F. Tenholder


Archive | 2015

__F11pulmonary andcritical care pearls "Lost" Tidal Volumesina71-Year-Old Ventilated Patient*

Michael F. Tenholder; William A. Erwin; Heidi S. Nelson

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Frank W. Ewald

Georgia Regents University

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Harold D. Jackson

Georgia Regents University

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William A. Erwin

Georgia Regents University

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Carolyn A. Hofer

Georgia Regents University

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J. Peter Rissing

Georgia Regents University

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James K. Smith

Georgia Regents University

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John H. Crosby

Georgia Regents University

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Joseph A. Fedrick

Georgia Regents University

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Kenneth J. Carney

Georgia Regents University

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