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Michael J. Hawkins

Trevena Inc

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Publication

Featured researches published by Michael J. Hawkins.

Journal of the American Chemical Society | 2002

Nonpeptide inhibitors of cathepsin G: optimization of a novel beta-ketophosphonic acid lead by structure-based drug design.

Michael N. Greco; Michael J. Hawkins; Eugene Powell; Harold R. Almond; Thomas W. Corcoran; Lawrence de Garavilla; Jack A. Kauffman; Rosario Recacha; Debashish Chattopadhyay; Patricia Andrade-Gordon; Bruce E. Maryanoff

Journal of Medicinal Chemistry | 2007

Discovery of Potent, Selective, Orally Active, Nonpeptide Inhibitors of Human Mast Cell Chymase

Michael N. Greco; Michael J. Hawkins; Eugene Powell; Harold R. Almond; L. de Garavilla; J Hall; Lisa Minor; Yuanping Wang; Thomas W. Corcoran; E. Di Cera; Angelene M. Cantwell; Savvas N. Savvides; Bruce P. Damiano; Bruce E. Maryanoff

Bioorganic & Medicinal Chemistry Letters | 2012

The design and synthesis of novel, phosphonate-containing transient receptor potential melastatin 8 (TRPM8) antagonists.

Jay M. Matthews; Ning Qin; Raymond W. Colburn; Scott L. Dax; Michael J. Hawkins; James J. McNally; Laura Reany; Mark A. Youngman; Judith Baker; Tasha Hutchinson; Yi Liu; Mary Lou Lubin; Michael P. Neeper; Michael R. Brandt; Christopher M. Flores

Bioorganic & Medicinal Chemistry Letters | 1999

Heterocycle-peptide hybrid compounds. Aminotriazole-containing agonists of the thrombin receptor (PAR-1)

David F. McComsey; Michael J. Hawkins; Patricia Andrade-Gordon; Michael F. Addo; Donna Oksenberg; Bruce E. Maryanoff

Archive | 2005

Novel inhibitors of chymase

Michael J. Hawkins; Michael N. Greco; Eugene Powell; Lawrence de Garavilla; Bruce E. Maryanoff

Archive | 2008

Novel phosphonic acid compounds as inhibitors of serine proteases

Michael N. Greco; Harold R. Almond; Michael J. Hawkins; Eugene Powell

Archive | 1997

Phenylalaninol derivatives for the treatment of central nervous system disorders

Scott L. Dax; Michael N. Greco; Michael J. Hawkins; Bruce E. Maryanoff; James J. McNally; Anna Vavouyios-Smith

Archive | 2002

Aminopyrrolidine sulfonamides as serine protease inhibitors

Michael N. Greco; Bruce E. Maryanoff; Michael J. Hawkins; Robert E. Boyd

Archive | 1999

Substituted heterocyclic acyl-tripeptides useful as thrombin receptor modulators

David F. McComsey; Bruce E. Maryanoff; Michael J. Hawkins

Organic Letters | 2006

Facile Dephosphonylation of β-Ketophosphonic Acids: Mechanistic Studies

Michael J. Hawkins; Eugene Powell; Gregory C. Leo; Diane A. Gauthier; Michael N. Greco; Bruce E. Maryanoff

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Collaboration

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Bruce E. Maryanoff

Janssen Pharmaceutica

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Michael N. Greco

University of Pittsburgh

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Eugene Powell

Janssen Pharmaceutica

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Scott L. Dax

University of Michigan

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David F. McComsey

Janssen Pharmaceutica

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Angelene M. Cantwell

Washington University in St. Louis

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Bruce P. Damiano

Johnson

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Savvas N. Savvides

Washington University in St. Louis

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Diane A. Gauthier

Johnson

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Gregory C. Leo

Monsanto

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