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Dive into the research topics where Michael J. Konkel is active.

Publication


Featured researches published by Michael J. Konkel.


Proceedings of the National Academy of Sciences of the United States of America | 2005

Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299

Chad J. Swanson; Thomas P. Blackburn; Xuexiang Zhang; Kang Zheng; Zhi-Qing David Xu; Tomas Hökfelt; Toni D. Wolinsky; Michael J. Konkel; Heidi Chen; Huailing Zhong; Mary W. Walker; Douglas A. Craig; Christophe Gerald; Theresa Branchek


Journal of Medicinal Chemistry | 2006

3-arylimino-2-indolones are potent and selective galanin GAL3receptor antagonists

Michael J. Konkel; Bharat Lagu; Lakmal W. Boteju; Hermogenes N. Jimenez; Stewart A. Noble; Mary W. Walker; Gamini Chandrasena; Thomas P. Blackburn; Sham S. Nikam; Jon Wright; Brian Edward Kornberg; Tracy Fay Gregory; Thomas A. Pugsley; Hyacinth Akunne; Kim Zoski; Lawrence D. Wise


Bioorganic & Medicinal Chemistry Letters | 2006

Amino substituted analogs of 1-phenyl-3-phenylimino-2-indolones with potent galanin Gal3 receptor binding affinity and improved solubility

Michael J. Konkel; Mathivanan Packiarajan; Heidi Chen; Upendra Topiwala; Hermogenes N. Jimenez; Ian Jamie Talisman; Heather Renee Coate; Mary W. Walker


Archive | 2002

Use of GALR3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods

Michael J. Konkel; John M. Werzel; Jamie Talisman


Journal of Medicinal Chemistry | 2005

Synthesis and Structure−Activity Relationship of Fluoro Analogues of 8-{2-[4-(4-Methoxyphenyl)piperazin-1yl]ethyl}-8-azaspiro[4.5]decane-7,9-dione as Selective α1d-Adrenergic Receptor Antagonists

Michael J. Konkel; John M. Wetzel; Marie Cahir; Douglas A. Craig; Stewart A. Noble; Charles Gluchowski


Archive | 2005

3-imino-2-indolones for the treatment of depression and/or anxiety

Michael J. Konkel; John M. Wetzel; Jamie Talisman


Archive | 2003

Use of GAL3 antagonist for treatment of depression

Thomas P. Blackburn; Michael J. Konkel; Lakmal W. Boteju; Ian Jamie Talisman; John M. Wetzel; Mathivana Packiarajan; Heidi Chen; Hermo Jimenez


Archive | 2001

Compounds specific for the human alpha1d adrenergic receptor and uses thereof

Michael J. Konkel; John M. Wetzel; Stewart A. Noble; Charles Gluchowski; Douglas A. Craig


Archive | 2002

Guanidines which are agonist/antagonist ligands for neuropeptide FF (NPFF) receptors

Joel K. Kawakami; John M. Wetzel; Lakmal W. Boteju; Michael J. Konkel; Honghe Wan; Stewart A. Noble


Archive | 2004

GAL3 receptor antagonists for the treatment of affective disorders

Michael J. Konkel; Thomas P. Blackburn; John M. Wetzel

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