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Dive into the research topics where Michael John Johnston is active.

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Featured researches published by Michael John Johnston.


Chemical Communications | 2007

Carbon–carbon bond forming reactions with substrates absorbed non-covalently on a cellulose chromatography paper support

Jonathon Hacon; Amanda J. Morris; Michael John Johnston; Stephen E. Shanahan; Mike D. Barker; Graham G. A. Inglis; Simon J. F. Macdonald

Reactions and purifications, including carbon-carbon bond forming reactions, can be carried out on a cellulose support on which the substrates are non-covalently absorbed.


Journal of Medicinal Chemistry | 2006

Dissociated nonsteroidal glucocorticoid receptor modulators; discovery of the agonist trigger in a tetrahydronaphthalene-benzoxazine series.

Mike Barker; Margaret Clackers; Royston Copley; Derek Anthony Demaine; Davina Humphreys; Graham G. A. Inglis; Michael John Johnston; Haydn Terence Jones; Michael V. Haase; David House; Richard Loiseau; Lesley Nisbet; Francois Pacquet; Philip Alan Skone; Stephen E. Shanahan; Dan Tape; Victoria Vinader; Melanie Washington; Iain Uings; Richard J. Upton; Iain M. McLay; Simon J. F. Macdonald


Journal of Medicinal Chemistry | 2005

Design and Synthesis of New Nonsteroidal Glucocorticoid Modulators through Application of an “Agreement Docking” Method

Mike Barker; Margaret Clackers; Derek Anthony Demaine; Davina Humphreys; Michael John Johnston; Haydn Terence Jones; Francois Pacquet; John M. Pritchard; Mark Salter; Stephen E. Shanahan; Philip Alan Skone; Victoria Vinader; Iain Uings; Iain M. McLay; Simon J. F. Macdonald


Archive | 2005

2,3-benzoxazin derivatives as non-steroidal glucocorticoid receptor modulators

David House; Graham George Adam Inglis; Michael John Johnston; Haydn Terence Jones; Simon J. F. Macdonald; Philip Alan Skone


Archive | 2005

Substituted oxazines as glucocorticoid receptor modulators

David House; Graham George Adam Inglis; Michael John Johnston; Haydn Terence Jones; Simon J. F. Macdonald; Philip Alan Skone


Journal of Medicinal Chemistry | 2007

Nonsteroidal Glucocorticoid Agonists : Tetrahydronaphthalenes with Alternative Steroidal A-Ring Mimetics Possessing Dissociated (Transrepression/Transactivation) Efficacy Selectivity

Keith Biggadike; Mohamed Boudjelal; Margaret Clackers; Diane Mary Coe; Derek Anthony Demaine; George William Hardy; Davina Humphreys; Graham G. A. Inglis; Michael John Johnston; Haydn Terence Jones; David House; Richard Loiseau; Deborah Needham; Philip Alan Skone; Iain Uings; Gemma Veitch; Gordon G. Weingarten; Iain M. McLay; Simon J. F. Macdonald


Archive | 2007

PYRROLO[2, 3-B]PYRIDIN-4-YL-BENZENESULFONAMIDE COMPOUNDS AS IKK2 INHIBITORS

Paul Bamborough; Michael David Barker; Sebastien Andre Campos; Richard Peter Charles Cousins; Paul Faulder; Heather Hobbs; Duncan S. Holmes; Michael John Johnston; John Liddle; Jeremy John Payne; John M. Pritchard; Caroline Whitworth


Archive | 2004

Non-steroidal infalmmation inhibitors

Michael David Barker; Derek Anthony Demaine; David House; Graham George Adam Inglis; Michael John Johnston; Haydn Terence Jones; Simon J. F. Macdonald; Iain Mcfarlane Mclay; Stephen E. Shanahan; Philip Alan Skone; Maria Victoria Vinader


Journal of Medicinal Chemistry | 1986

Chloroalanyl antibiotic peptides: antagonism of their antimicrobial effects by L-alanine and L-alanyl peptides in gram-negative bacteria.

Kam Sing Cheung; William E. Boisvert; Stephen A. Lerner; Michael John Johnston


Journal of Biological Chemistry | 1986

Mechanisms of action of chloroalanyl antibacterial peptides. Identification of the intracellular enzymes inactivated on treatment of Escherichia coli JSR-O with the dipeptide beta Cl-LAla-beta Cl-LAla.

William E. Boisvert; Kam Sing Cheung; Stephen A. Lerner; Michael John Johnston

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