Michael L. Maddox

Highly selective γ-alkylation of triisopropylsilylallyl anion. Synthesis of α-triisopropylsilyl aldehydes.

Abstract The reaction of triisopropylsilylallyllithium with alkyl halides took place with considerably greater γ-selectivity than reported for trimethylsilyl allyllithium. Silica gel induced rearrangement of the epoxides 5 derived from the alkylation products 3 gave α-triisopropylsilyl aldehydes 6 by a process in which silyl group transposition occurred with predominant inversion at the migration terminus.

One step synthesis of 3,8-methanoaza[10]annulene derivatives

Abstract The cycloaddition of benzocyclopropene with 1,2,4-triazines bearing one or more electron accepting substituents produces the corresponding substituted 3,8-methanoaza[10]annulene derivatives.