Michael Russell Mullane

Needle Tract Seeding Following Irreversible Electroporation (IRE) of Metastatic Colorectal Carcinoma to the Liver

Irreversible electroporation (IRE) is an increasingly popular tissue ablative technology that creates pores in the cell membrane by means of electricity. For hepatocellular carcinoma or metastatic colorectal cancer to the liver, it can target lesions near ducts and vessels without risk of thrombosis or stricture. Its non-thermal mechanism, however, may allow for increased rates of needle tract seeding. We present the first known case report of peritoneal needle tract seeding following IRE. Case

Gastric Cancer in a Patient with Laparoscopic Adjustable Gastric Band: Case Report and Review of Literature

Obesity has reached a pandemic proportion across continents [1]. Bariatric surgery is a safe and effective procedure that results in sustained weight loss and hence reduction in obesity related comorbidities and mortality [2]. It is also associated with reducing the risk of certain cancers, including gastrointestinal cancers, in formerly obese patients [2]. However, there are a few case reports of late occurrence of gastric cancer in patients who underwent various kinds of bariatric surgery [3, 4]. Here, we report a patient who presented with an umbilical nodule and was subsequently diagnosed with gastric cancer, almost a decade after bariatric surgery. In this report, we will review literature pertaining to this association and possible mechanism involved in the development of gastric cancer in such patients.

Metastatic spread from squamous cell carcinoma of the hypopharynx to the totally implantable venous access port insertion site: Case report and review of literature

The totally implantable venous access port plays a crucial role in delivering chemotherapy in the outpatient setting. Here, we report the first case of a patient with hypopharyngeal tumor who developed chest wall metastasis over the totally implantable venous access port inserted in the internal jugular vein.

Metastasis of cervical cancer to breast: A case report and review of literature

Metastasis to the breast from an extra-mammary malignancy has been documented in literature, however cervical cancer metastasis to the breast is very rare. Thirty-eight cases of metastatic deposit to the breast from cervical cancer have been reported in literature. Though most patients present with a breast lump, it is very difficult to clinically distinguish a primary breast malignancy from a metastatic deposit. Histopathology of the tissue, aided with immune-histochemical staining pattern provides a definitive diagnosis. Our patient, a 51-year old woman presented with breast lump and history of post-menopausal bleeding. Upon further workup, the patient was diagnosed with cervical cancer. The mammogram and ultrasound of the breast showed multiple lumps within the breast. Histopathology of the breast mass showed metastatic deposit in the breast from cervical cancer. The patient was treated with radiation therapy to the cervix along with concurrent chemotherapy for local control of pain. After completion of local treatment, she started systemic chemotherapy, however she developed health-care associated pneumonia and subdural hematoma leading to deterioration in her performance status. The patient opted for hospice care and died 2 months later. In this report, we will review the presentation of the 38 cases reported in literature and the imaging and histopathologic findings of metastatic deposits to the breast.