Michael Stephen Pacey
Pfizer
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Michael Stephen Pacey.
Bioorganic & Medicinal Chemistry | 2000
B.J. Banks; Bernard Frank Bishop; Nigel A. Evans; Stephen Paul Gibson; A.C. Goudie; K.A.F. Gration; Michael Stephen Pacey; D.A. Perry; M.J. Witty
Evaluation of a wide range of avermectin derivatives for flea activity in an in vitro feeding screen using the cat flea, Ctenocephalides felis, revealed a narrow structure-activity relationship (SAR) with activity surprisingly associated with monosaccharides and especially their C-5-oximes. We discovered commercially exploitable flea activity in a single compound, selamectin 33, which also possessed the necessary antiparasitic spectrum and margin of safety for development as a broad-spectrum companion animal endectocide.
The Journal of Antibiotics | 1992
Mark A. Maxell; Bernard Frank Bishop; Patricia Bryce; Kenneth A. F. Oration; Hamida Kara; Robert A. Monday; Michael Stephen Pacey; David Austen Perry; Yasuhiro Kojima; Hiroshi Maeda; Satoshi Nishiyama; Junsuke Tone; Liang H. Huang
A family of novel milbemycins possessing C-13 beta-acyloxy substitution was produced by Streptomyces hygroscopicus ATCC 53718. These compounds were detected by HPLC diode array analysis and possess anthelmintic and ectoparasiticidal activity. The origin of the oxygen atom at C-13 is discussed.
The Journal of Antibiotics | 1991
Christopher J. Dutton; Stephen Paul Gibson; Alexander Crossan Goudie; Kelvin Scott Holdom; Michael Stephen Pacey; John C. Ruddock; John D. Bu'Lock; Michelle Richards
Archive | 1994
Bernard Frank Bishop; Michael Stephen Pacey; David Austen Perry
Archive | 1997
Peter Francis Leadlay; James Staunton; Jesus Cortes; Michael Stephen Pacey
The Journal of Antibiotics | 1998
Michael Stephen Pacey; John P. Dirlam; Roderick W. Geldart; Peter F. Leadlay; Hamish McArthur; Ellen McCormick; Robert A. Monday; Thomas N. O'Connell; James Staunton; Toby Winchester
Archive | 2001
Bernard Joseph Banks; Mark Andrew Haxell; Graham Lunn; Michael Stephen Pacey; Lee R. Roberts
The Journal of Antibiotics | 1999
Ian Parsons; Jeremy R. Everett; Michael Stephen Pacey; John C. Ruddock; Alistair G. Swanson; Christine Thompson
The Journal of Antibiotics | 2000
Michael Stephen Pacey; Christopher J. Dutton; Robert A. Monday; John C. Ruddock; Graham Smith
Archive | 2001
Bernard Joseph Banks; Nathan Anthony Logan Chubb; James John Eshelby; Michael Stephen Pacey; Darren John Schulz
