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Featured researches published by Michal Elovitz.


Obstetrics & Gynecology | 2016

Ultrasound Measurement of the Fetal Adrenal Gland as a Predictor of Spontaneous Preterm Birth

Matthew K. Hoffman; Ozhan Turan; Corette B. Parker; Ronald J. Wapner; Deborah A. Wing; David M. Haas; M. Sean Esplin; Samuel Parry; William A. Grobman; H. Simhan; Stephen A. Myers; Tommy E. Holder; Pamela Rumney; Christian Litton; Robert Silver; Michal Elovitz; Alan M. Peaceman; Stephen Emery; Brian M. Mercer; Matthew A. Koch; George R. Saade

OBJECTIVE: To estimate whether ultrasound measurement of the fetal adrenal gland remote from delivery in asymptomatic women can accurately predict spontaneous preterm birth. METHODS: We conducted a prospective multicenter observational nested cohort study of asymptomatic nulliparous women with a singleton pregnancy to study adverse pregnancy outcomes. Between 22 0/7 and 30 6/7 weeks of gestation, credentialed ultrasonographers measured the width (width), length (length), and, when able, depth (depth) of the “fetal zone” of the fetal adrenal gland as well as the width (Width), length (Length), and depth (Depth) of the total gland. We used the ratios of each measurement (width/Width, length/Length, and depth/Depth) to control for variation in adrenal size by gestational age. The accuracy of each ratio measurement in predicting spontaneous preterm birth at less than 37 0/7 weeks of gestation and spontaneous preterm birth at less than 34 0/7 weeks of gestation was assessed by receiver operating characteristic curves using area under the curve. RESULTS: Pregnancy outcomes were available for 1,697 women with one or more fetal adrenal gland measurements. Spontaneous preterm birth at less than 37 0/7 weeks of gestation and spontaneous preterm birth at less than 34 0/7 weeks of gestation occurred in 82 (4.8%) and six women (0.4%), respectively. None of the fetal adrenal gland measurements distinguished spontaneous preterm birth from term birth. The areas under the curve (95% confidence intervals) for spontaneous preterm birth at less than 37 0/7 weeks of gestation were 0.51 (0.45–0.58), 0.50 (0.44–0.56), and 0.52 (0.41–0.63) for width/Width, length/Length, and depth/Depth ratios, respectively. The areas under the curve for spontaneous preterm birth at less than 34 0/7 weeks of gestation were 0.52 (0.25–0.79) and 0.55 (0.31–0.79) for width/Width and length/Length ratios, respectively. Additionally, none of the means of the gland measurements were statistically different between those delivering at term and spontaneous at preterm (P>.05). CONCLUSION: Fetal adrenal size, as measured by ultrasonography between 22 0/7 and 30 6/7 weeks of gestation, is not predictive of spontaneous preterm birth in asymptomatic nulliparous women.


/data/revues/00029378/v214i1sS/S0002937815013228/ | 2015

5: Foley or Misoprostol for the Management of Induction (The ‘FOR MOMI’ trial): A four-arm randomized clinical trial

Lisa D. Levine; Mary Sammel; Samuel Parry; Catherine T. Williams; Michal Elovitz; Sindhu Srinivas


/data/revues/00029378/v216i1sS/S0002937816319263/ | 2017

Iconographies supplémentaires de l'article : 61: Cardiac dysfunction in preeclampsia is present at diagnosis and persists postpartum

Lisa D. Levine; Katheryne Downes; Zolt Arany; Bonnie Ky; Michal Elovitz


/data/revues/00029378/v216i1sS/S0002937816318798/ | 2017

Iconographies supplémentaires de l'article : 10: Distinct microbiota in the cervicovaginal space are associated with spontaneous preterm birth: findings from a large cohort and validation study

Michal Elovitz; Pawel Gajer; Katheryne Downes; Jacques Ravel


Archive | 2016

Additional file 3: Figure S2. of Comparison of placenta samples with contamination controls does not provide evidence for a distinct placenta microbiota

Abigail Lauder; Aoife M. Roche; Scott Sherrill-Mix; Aubrey Bailey; Alice Laughlin; Kyle Bittinger; Rita Leite; Michal Elovitz; Samuel Parry; Frederic D. Bushman


Archive | 2015

obesityinvolved in the fetal response to maternal Identification and comparative analyses of myocardial

Peter W. Nathanielsz; Leslie Myatt; Mark J. Nijland; Alina Maloyan; Steven Huffman; Neda Ghaffari; Samuel Parry; Michal Elovitz; Celeste Durnwald; Victoria H. J. Roberts; Antonio Frias; Kevin L. Grove


/data/revues/00029378/unassign/S0002937814010205/ | 2014

Does stage of labor at time of cesarean delivery affect risk of subsequent preterm birth

Lisa D. Levine; Mary Sammel; Adi Hirshberg; Michal Elovitz; Sindhu Srinivas


/data/revues/00029378/v208i1sS/S0002937812019059/ | 2012

656: Excessive weight gain and hypertensive disorders of pregnancy: a modifiable risk factor

Suchitra Chandrasekaran; Lisa D. Levine; Celeste Durnwald; Michal Elovitz; Sindhu Srinivas


/data/revues/00029378/v208i1sS/S0002937812018960/ | 2012

Iconography : 647: MicroRNA 210 levels in the first and second trimester of pregnancy are accurate predictors of pregnancy related hypertension

Michal Elovitz; Lauren Anton; Jamie Bastek; Nadav Schwartz


/data/revues/00029378/v208i1sS/S0002937812017450/ | 2012

496: Crime and property vacancy are not risk factors of preterm birth in Philadelphia, Pennsylvania

Jamie Bastek; Mary Sammel; Sindhu Srinivas; Tara Jackson; Meghan McShea; Meghan Ryan; Michal Elovitz

Collaboration


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Sindhu Srinivas

Hospital of the University of Pennsylvania

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Jamie Bastek

University of Pennsylvania

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Ella Ofori

University of Pennsylvania

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Juan Gonzalez

Hospital of the University of Pennsylvania

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Hua Xu

University of Pennsylvania

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Mary Sammel

National Institutes of Health

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Brianna Lyttle

University of Pennsylvania

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Irina Burd

Johns Hopkins University School of Medicine

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Lauren Anton

University of Pennsylvania

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