Michel Erpicum

History and clinical features of atypical myopathy in horses in Belgium (2000-2005)

BACKGROUND The emergent nature of atypical myopathy or atypical myoglobinuria (AM) necessitates precise description of its clinical and epidemiologic features. PURPOSE To define key features of AM to help practitioners recognize the disease and to advise owners to take preventive measures. ANIMALS Belgian cases of AM confirmed by histology (CC horses; n = 57) from autumn 2000 to spring 2005 were included in the study. Co-grazing horses (Co-G horses; n = 77) that remained free of any abnormal clinical signs constituted a control group. METHODS History, environmental characteristics, clinical signs, and laboratory results associated with AM were determined by a retrospective case series study. RESULTS Young horses in poor or normal body condition were found to be at risk for AM. Pastures were characterized by poor natural drainage and vegetation of low nutritional value. Features of AM were seasonal occurrence, apparent link with weather conditions (ie, lack of solar radiation with no heavy frost and an excess of precipitation or relative humidity), sudden onset of clinical signs, and rapid death. Evaluation of serum creatine kinase activity indicated severe muscle destruction in CC horses and subclinical disease in a few Co-G horses. CONCLUSIONS The association of AM with specific environmental conditions and individual animals suggests that young horses should not be pastured on bare premises subject to humidity when the weather has been very wet and cold for several days. Management of AM outbreaks should include control of Co-G horses who are apparently healthy.

Studying interactions between climate variability and vegetation dynamic using a phenology based approach

Abstract In this paper we investigated if and how a signature of climate control on vegetation growth can be individualized at regional scale using time series of SPOT-VEGETATION NDVI and ECMWF meteorological data. Twelve regions characterized by dominant and stable cropland or grassland covers were selected in Europe and Africa. Our results show that the relationship between NDVI and meteorological parameters is highly complex and significantly vary trough the phenological cycle of the plants. Hence, interactions between vegetation dynamics and climate variability must be studied at a smaller time scale in order to identify properly the limiting factors to vegetation growth. Using NDVI metrics, vegetative phases (from green-up to maximum NDVI) and reproductive phases (from maximum NDVI to maturity) were identified for each region. Cross-correlation analysis revealed that, in most of the cases, the best scores of Pearsons r are obtained when we considered the vegetative phase (from green-up to maximum of NDVI) and the reproductive phase (from maximum of NDVI to maturity) separately. We also showed that climatic constraints identified using yearly proxies of climate and vegetation do not depict correctly or completely the climate control on vegetation development. In that sense the complexity of the climate-vegetation relationship, which is spatially and temporally variable, is well underlined in this study.

Current and future atmospheric circulation at 500 hPa over Greenland simulated by the CMIP3 and CMIP5 global models

The Greenland ice sheet is projected to be strongly affected by global warming. These projections are either issued from downscaling methods (such as Regional Climate Models) or they come directly from General Circulation Models (GCMs). In this context, it is necessary to evaluate the accuracy of the daily atmospheric circulation simulated by the GCMs, since it is used as forcing for downscaling methods. Thus, we use an automatic circulation type classification based on two indices (Euclidean distance and Spearman rank correlation using the daily 500 hPa geopotential height) to evaluate the ability of the GCMs from both CMIP3 and CMIP5 databases to simulate the main circulation types over Greenland during summer. For each circulation type, the GCMs are compared to three reanalysis datasets on the basis of their frequency and persistence differences. For the current climate (1961–1990), we show that most of the GCMs do not reproduce the expected frequency and the persistence of the circulation types and that they simulate poorly the observed daily variability of the general circulation. Only a few GCMs can be used as reliable forcings for downscaling methods over Greenland. Finally, when applying the same approach to the future projections of the GCMs, no significant change in the atmospheric circulation over Greenland is detected, besides a generalised increase of the geopotential height due to a uniform warming of the atmosphere.

Photosynthesis of Scenedesmus obliquus in outdoor open thin-layer cascade system in high and low CO2 in Belgium

Two outdoor open thin-layer cascade systems operated as batch cultures with the alga Scenedesmus obliquus were used to compare the productivity and photosynthetic acclimations in control and CO2 supplemented cultures in relation with the outdoor light irradiance. We found that the culture productivity was limited by CO2 availability. In the CO2 supplemented culture, we obtained a productivity of up to 24gdwm(-2)day(-1) and found a photosynthetic efficiency (value based on the PAR solar radiation energy) of up to 5%. In the CO2 limited culture, we obtained a productivity of up to 10gdwm(-2)day(-1) while the photosynthetic efficiency was up to 3.3% and decreased to 2.1% when the integrated daily PAR increased. Fluorescence and oxygen evolution measurements showed that ETR and oxygen evolution light saturation curves, as well as light-dependent O2 uptake were similar in algal samples from both cultures when the CO2 limitation was removed. In contrast, we found that CO2 limitation conducted to a decreased PSII photochemical efficiency and an increased light-induced heat-dissipation in the control culture compared to the CO2 supplemented culture. These features are in line with a lower light use efficiency and may therefore contribute to the lower productivity observed in absence of CO2 supplementation in outdoor mass cultures of S. obliquus.

Estimation of the Sea Level Rise by 2100 Resulting from Changes in the Surface Mass Balance of the Greenland Ice Sheet

The Surface Mass Balance (SMB) can be seen, in first approximation, as the water mass gained by the winter snowfall accumulation minus the mass lost by the meltwater run-off in summer. The mass gain from rainfall as well as the mass loss from erosion from the net water fluxes (the sum of the evaporation, sublimation, deposition and condensation) and from the wind (blowing snow) are negligible in the SMB equation of the Greenland Ice Sheet (GrIS) compared to the snowfall and the melt (Box et al., 2004). The ice sheet mass balance takes also into account the mass loss from iceberg calving. Consequences of a warmer climate on the Greenland ice sheet SMB will be a thickening inland, due to increased solid precipitation, and a thinning at the Greenland ice sheet periphery, due to an increasing surface melt. A climatic warming increases the snow and ice melting in summer but it enhances also evaporation above the ocean. This leads to higher moisture transport inland and, consequently, higher precipitation. The response of the iceberg calving to the climate change could be an acceleration of the glacier flow (Nick et al., 2009; Zwally et al., 2002) but these projections are very uncertain (Sundal et al., 2011) and a lot of developments are still needed in the glaciology models for improving our knowledge and modelling of the Greenland ice sheet dynamics. That is why we will focus our study only on the SMB of the Greenland ice sheet. The IPCC (Intergovernmental Panel on Climate Change) projects, in response to global warming induced by human activities, that the run-off increase will exceed the precipitation increase and therefore that the currently observed surface melting of the Greenland ice sheet (Fettweis et al., 2011b; Tedesco et al., 2011; Van den Broeke et al., 2009) will continue and intensify during the next decades (IPCC, 2007). An increasing freshwater flux from the Greenland ice sheet melting could perturb the thermohaline circulation (by reducing the density contrast driving this last one) in the North Atlantic including the drift which tempers the European climate. In addition, an enduring Greenland ice sheet melting, combined with the thermal expansion of the oceans and the melt of continental glaciers, will raise the sea level with well-known consequences for countries such as the Netherlands, Bangladesh,... The contribution of the Greenland ice sheet SMB decrease to the sea level rise is currently evaluated to be 5-10 cm by 2100 (Gregory and Huybrechts, 2006; Fettweis et al., Estimation of the Sea Level Rise by 2100 Resulting from Changes in the Surface Mass Balance of the Greenland Ice Sheet 25

Multi-Months Cycles Observed in Climatic Data

Climatic variations happen at all time scales and since the origins of these variations are usually of very complex nature, climatic signals are indeed chaotic data. The identification of the cycles induced by the natural climatic variability is therefore a knotty problem, yet the knowing of these cycles is crucial to better understand and explain the climate (with interests for weather forecasting and climate change projections). Due to the non-stationary nature of the climatic time series, the simplest Fourier-based methods are inefficient for such applications (see e.g. Titchmarsh (1948)). This maybe explains why so few systematic spectral studies have been performed on the numerous datasets allowing to describe some aspects of the climate variability (e.g. climatic indices, temperature data). However, some recent studies (e.g. Matyasovszky (2009); Palus & Novotna (2006)) show the existence of multi-year cycles in some specific climatic data. This shows that the emergence of new tools issued from signal analysis allows to extract sharper information from time series. Here, we use a wavelet-based methodology to detect cycles in air-surface temperatures obtained from worldwide weather stations, NCEP/NCAR reanalysis data, climatic indices and some paleoclimatic data. This technique reveals the existence of universal rhythms associated with the periods of 30 and 43 months. However, these cycles do not affect the temperature of the globe uniformly. The regions under the influence of the AO/NAO indices are influenced by a 30 months period cycle, while the areas related to the ENSO index are affected by a 43 months period cycle; as expected, the corresponding indices display the same cycle. We next show that the observed periods are statistically relevant. Finally, we consider some mechanisms that could induce such cycles. This chapter is based on the results obtained in Mabille & Nicolay (2009); Nicolay et al. (2009; 2010).

The Climate of Belgium and Luxembourg

The present climate of Belgium and Luxembourg is shown to be oceanic warm-temperate, benefitting from the warming effect of the North Atlantic Drift. Mean annual air temperatures are around 10 ℃ and vary spatially mainly as a function of elevation. Annual temperature amplitudes are in the 13–17 °C range. Annual rainfall depths vary from ~700 mm in western Belgium to 1300–1400 mm in the wettest areas of NE and SW Ardenne. Belgium and Luxembourg are located in the zone of seasonal shift of the north polar front and the associated mid-latitude, or polar front jet stream.

Sunlight irradiance and habituation of visual evoked potentials in migraine: The environment makes its mark

Background Migraine is a complex multifactorial disease that arises from the interaction between a genetic predisposition and an enabling environment. Habituation is considered as a fundamental adaptive behaviour of the nervous system that is often impaired in migraine populations. Given that migraineurs are hypersensitive to light, and that light deprivation is able to induce functional changes in the visual cortex recognizable through visual evoked potentials habituation testing, we hypothesized that regional sunlight irradiance levels could influence the results of visual evoked potentials habituation studies performed in different locations worldwide. Methods We searched the literature for visual evoked potentials habituation studies comparing healthy volunteers and episodic migraine patients and correlated their results with levels of local solar radiation. Results After reviewing the literature, 26 studies involving 1291 participants matched our inclusion criteria. Deficient visual evoked potentials habituation in episodic migraine patients was reported in 19 studies. Mean yearly sunlight irradiance was significantly higher in locations of studies reporting deficient habituation. Correlation analyses suggested that visual evoked potentials habituation decreases with increasing sunlight irradiance in migraine without aura patients. Conclusion Results from this hypothesis generating analysis suggest that variations in sunlight irradiance may induce adaptive modifications in visual processing systems that could be reflected in visual evoked potentials habituation, and thus partially account for the difference in results between studies performed in geographically distant centers. Other causal factors such as genetic differences could also play a role, and therefore well-designed prospective trials are warranted.