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Dive into the research topics where Michio Nakanishi is active.

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Featured researches published by Michio Nakanishi.


Life Sciences | 1973

Protective effect of anti-anxiety drugs against hypoxia

Michio Nakanishi; Hiroshi Yasuda; Tatsumi Tsumagari

Abstract The effect of psychotropic agents was studied on the survival of mice subjected to hypoxia. A significant prolongation of the survival time was observed in the animals pretreated with anti-anxiety drugs. However, anti-psychotic drugs or thymoleptics failed to exert such elongation effect under the same condition. The order of potency on anti-hypoxia activity was: Y-6047 = diazepam = nitrazepam > oxazapem > chlordiazepoxide > medazepam, namely in the ratio of 30 : 10 : 3 : 1, approximately. A relationship between anti-anxiety activity and anti-hypoxia activity is also discussed.


Journal of Medicinal Chemistry | 1973

Studies on psychotropic drugs. 18. Synthesis and structure-activity relationships of 5-phenyl-1,3-dihydro-2H-thieno(2,3-e) (1,4) diazepin-2-ones.

Michio Nakanishi; Tetsuya Tahara; Kazuhiko Araki; Masami Shiroki; Tatsumi Tsumagari; Yukio Takigawa


Biochemical Pharmacology | 1975

Inhibitory effects by anti-inflammatory drugs on enzyme release from rabbit polymorphonuclear leukocyte lysosomes

Michio Nakanishi; K.Azuhiro Goto


Archive | 1973

Substituted alkanoic acids and derivatives

Michio Nakanishi; Takanori Oe; Mineo Tsuruda


Biochemical Pharmacology | 1971

Potentiation of the ADP-induced platelet aggregation by collagen and its inhibition by a tetrahydrothienopyridine derivative (Y-3642).

Michio Nakanishi; Hiroshi Imamura; Kazuhiro Goto


Archive | 1970

3-oxo-1-oxa-4,8-diazaspiro(4.5)decanes

Michio Nakanishi; Katsuo Arimura; Hideki Ao


Archive | 1970

11-(4-heterocyclic alkyl substituted-1-piperazinyl) dibenzooxazepines

Michio Nakanishi; Tomohiko Munakata; Yutaka Maruyama; Shinro Setoguchi


Archive | 1974

Substituted phenylalkanoic acids and derivatives

Michio Nakanishi; Tomio Muro; Tohru Nakao; Kiyoshi Ogawa


Journal of Medicinal Chemistry | 1970

Studies of piperidine derivatives. I.

Michio Nakanishi; Chiaki Tashiro; Tomohiko Munakata; Kazuhiko Araki; Tatsumi Tsumagari; Hiroshi Imamura


Archive | 1966

Polyol esters of alpha-aryloxyalkanoic acids

Toshihiro Kobayakawa; Tsuneto Kuriyama; Michio Nakanishi; Takanori Oe

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