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Dive into the research topics where Miguel Pishnamaz is active.

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Featured researches published by Miguel Pishnamaz.


Journal of Medical Case Reports | 2012

Low back pain during pregnancy caused by a sacral stress fracture: a case report.

Miguel Pishnamaz; Richard Martin Sellei; Roman Pfeifer; Philipp Lichte; Hans Christoph Pape; Philipp Kobbe

IntroductionSacral stress fractures are a rare but well known cause of low back pain. This type of fracture has also been observed as a postpartum complication. To date, no cases of intrapartum sacral stress fractures have been described in the literature.Case presentationWe report the case of a 26-year-old Caucasian European primigravid patient (30 weeks and two days of gestation) who presented to our outpatient clinic with severe low back pain that had started after a downhill walk 14 days previously. She had no history of trauma. A magnetic resonance imaging scan revealed a non-displaced stress fracture of the right lateral mass of her sacrum. Following her decision to opt for non-operative treatment, our patient received an epidural catheter for pain control. The remaining course of her pregnancy was uneventful and our patient gave birth to a healthy child by normal vaginal delivery.ConclusionsWe conclude that a sacral stress fracture must be considered as a possible cause of low back pain during pregnancy.


Scandinavian Journal of Surgery | 2013

A Meta-Analysis of Operative Versus Nonoperative Treatment In 463 Scapular Neck Fractures

Thomas Dienstknecht; Klemens Horst; Miguel Pishnamaz; Richard Martin Sellei; Philipp Kobbe; A. Berner

Background and Aims: Treatment of scapular neck fractures remains controversial. Advantages of surgical treatments, such as anatomical restoration of fracture displacement, are counterbalanced by approach morbidity. We conducted a meta-analysis of 463 scapular neck fractures and compared clinical, functional, and radiographical outcomes in operatively and nonoperatively treated scapular neck fractures. Material and Methods: A literature search was conducted, including the databases PubMed/MEDLINE, Embase, and the Cochrane Database of Systematic Reviews. Manuscripts were included if they reported a precise description of treatment, complications, functional outcomes, and/or radiographic evaluation. Data about day-to-day activities, level of pain-freeness, range of motion, functional grading, and radiographical assessment were pooled and compared using fixed effects models. Results and Conclusions: A total of 22 manuscripts were relevant, including 1 prospective cohort study and 21 retrospective studies. The studies showed a high heterogeneity in the result assessment. Most patients had concomitant injuries. In total, 234 out of the 463 fractures were treated operatively. Pain-freeness and radiographic outcome measurements were significantly better in the operatively treated group, whereas range of motion was significantly improved in the nonoperative treated patients. Complication rate for surgical treatment was about 10%. From the achievable data, there was no bias detected when comparing the two treatment groups. However, those data could not be analyzed for all included studies. For the same reason, the role of additional surgical treatment for concomitant injuries to the shoulder girdle could not be cleared completely. Caution should be exercised, and individual injury patterns have to be taken into consideration when considering the best treatment options.


Journal of Trauma Management & Outcomes | 2012

Outcome after thoracoscopic ventral stabilisation of thoracic and lumbar spine fractures.

Roman Pfeifer; Miguel Pishnamaz; Derek Dombroski; Nicole Heussen; Hans-Christoph Pape; Bernhard Schmidt-Rohlfing

Background and PurposeThoracoscopic-assisted ventral stabilisation for thoracolumbar fractures has been shown to be associated with decreased recovery time and less morbidity when compared with open procedures. However, there are a limited number of studies evaluating late clinical and radiological results after thoracoscopic spinal surgery.MethodsWe performed an analysis of the late outcomes of thoracolumbar fractures after minimally invasive thoracoscopic ventral instrumentation. Between August 2003 and December 2008, 70 patients with thoracolumbar fractures (T5-L2) underwent ventral thoracoscopic stabilisation. Tricortical bone grafts, anterior plating systems (MACS-System), and cage implants were used for stabilisation. Outcomes measured include radiologic images (superior inferior endplate angle), Visual Analogue Scale (VAS), VAS Spine Score, quality of life scores SF-36 and Oswestry Disability Index (ODI).ResultsForty seven patients (67%, 47 out of 70) were recruited for the follow up evaluation (2.2 ± 1.5 years). Lower VAS Spine scores were calculated in patients with intra- or postoperative complications (44.7 (± 16.7) vs. 65.8 (± 24.5), p=0.0447). There was no difference in outcome between patients treated with bone graft vs. cage implants. Loss of correction was observed in both bone graft and titanium cage groups.InterpretationThe present study demonstrates diminished long-term quality of life in patients treated with thoracoscopic ventral spine when compared with the outcome of german reference population. In contrast to the other patients, those patients without intra-operative or post-operative complications were associated with improved outcome. The stabilisation method (bone graft versus spinal cage) did not affect the long-term clinical or radiographic results in this series.


PLOS ONE | 2017

Microcirculation in open vs. minimally invasive dorsal stabilization of thoracolumbar fractures

Bergita Ganse; Miguel Pishnamaz; Philipp Kobbe; Christian Herren; Gertraud Gradl-Dietsch; Franziska Böhle; Bernd Johannes; Bong-Sung Kim; Klemens Horst; Matthias Knobe

Standard open and percutaneous minimally invasive surgical procedures co-exist in the treatment of fractures of the thoracolumbar spine. Shorter skin incisions just above the pedicles are used in minimally invasive procedures. Full-length skin incisions and invasive preparations are applied in the standard open approach. While both methods show equivalent rates of intraoperative surgical complications and comparable clinical and radiological outcomes, blood loss and operation time have shown to be decreased in minimally invasive treatment. However, no study so far has investigated differences in microcirculation. This study hypothesized less impairment of microcirculation in the minimally invasive approach compared to the open approach and an improvement of microcirculation over time. A prospective cohort study was conducted using non-invasive laser-Doppler spectrophotometry (an O2C “oxygen to see” device) for measurement of cutaneous and subcutaneous blood oxygenation (SO2), haemoglobin concentration (Hb), and blood flow at depths of 2, 8, and 15 mm at six locations on the skin. Measurements were performed before surgery, 8 and 24 h after surgery, and 2, 4, 7, 12 and 20 days after surgery, however the number of patients measured decreased towards the later time points. Forty patients were included in the study, 20 with each approach (18 females and 22 males). Pair-wise comparison of the types of surgical procedure for each measurement point revealed a significantly higher flow value in the minimally invasive group at one of the measurement points located between the incisions (P = .041). The point-wise analyses of SO2 and Hb did not show significant differences between the approaches. In conclusion, significantly albeit moderately higher flow values could be found in minimally invasive procedures compared to open operations of thoracolumbar fractures in the area of skin that is spared by the incisions.


Clinical Biomechanics | 2017

Biomechanical testing of a PEEK-based dynamic instrumentation device in a lumbar spine model

Christian Herren; Agnes Beckmann; Sabine Meyer; Miguel Pishnamaz; Marion Mundt; Rolf Sobottke; Andreas Prescher; Marcus Stoffel; Bernd Markert; Philipp Kobbe; Hans-Christoph Pape; P. Eysel; Jan Siewe

Background The purpose of this study was to investigate the range‐of‐motion after posterior polyetheretherketone‐based rod stabilisation combined with a dynamic silicone hinge in order to compare it with titanium rigid stabilisation. Methods Five human cadaveric lumbar spines with four vertebra each (L2 to L5) were tested in a temperature adjustable spine‐testing set‐up in four trials: (1) native measurement; (2) kinematics after rigid monosegmental titanium rod instrumentation with anterior intervertebral bracing of the segment L4/5; (3) kinematics after hybrid posterior polyetheretherketone rod instrumentation combined with a silicone hinge within the adjacent level (L3/4) and (4) kinematics after additional decompression with laminectomy of L4 and bilateral resection of the inferior articular processes (L3). During all steps, the specimens were loaded quasi‐statically with 1°/s with pure moment up to 7.5 Nm in flexion/extension, lateral bending and axial rotation. Findings In comparison to the native cadaveric spine, both the titanium device and polyetheretherketone‐based device reduce the range‐of‐motion within the level L4/5 significantly (flexion/extension: reduction of 77%, p < 0.001; lateral bending: reduction of 62%, p < 0.001; axial rotation: reduction of 71%, p < 0.001). There was a clear stabilisation effect after hybrid‐instrumentation within the level L3/4, especially in flexion/extension (64%, p < 0.001) and lateral bending (62%, p < 0.001) but without any effect on the axial rotation. Any temperature dependency has not been observed. Interpretation Surprisingly, the hybrid device compensates for laminectomy L4 and destabilising procedure within the level L3/4 in comparison to other implants. Further studies must be performed to show its effectiveness regarding the adjacent segment instability. HighlightsThe PEEK‐based and the titanium rod reduce the range‐of‐motion after instrumentation.No signs of hypermobility have been observed in the superior adjacent level.The dynamic construct constrained motions in flexion/extension and lateral bending.Partial resection of the facet joint has no influence on stability.Any temperature dependency has not been observed.


European Journal of Medical Research | 2015

Fracture of the lesser trochanter as a sign of undiagnosed tumor disease in adults

Christian Herren; Christian Weber; Miguel Pishnamaz; Thomas Dienstknecht; Philipp Kobbe; Frank Hildebrand; Hans Christoph Pape

Isolated avulsion fractures of the pelvic ring are rare and occur predominantly in adolescent athletes. Isolated fractures of the lesser trochanter are reported to be pathognomic for tumor diseases in adults. We present a case of a female patient with an isolated avulsion of the lesser trochanter after treatment by her chiropractor. After staging examination, we determine the diagnosis of a left-sided carcinoma of the mamma. Additional imaging shows multiple metastases in liver, spine and pelvis. Palliative therapy has started over the course of time. We suggest, on suspicion of a malignant metastatic process, further investigation.


PLOS ONE | 2017

Thoracic trauma now and then: A 10 year experience from 16,773 severely injured patients

Klemens Horst; Hagen Andruszkow; Christian Weber; Miguel Pishnamaz; Christian Herren; Qiao Zhi; Matthias Knobe; Rolf Lefering; Frank Hildebrand; Hans-Christoph Pape

Background and purpose Thoracic trauma remains to be a relevant injury to the polytraumatised patient. However, literature regarding how far changes in clinical guidelines for pre- and in-hospital trauma management and diagnostic procedures affect the outcome of multiple injured patients with severe chest injury during a long-term observation period is sparse. Methods Multiple traumatised patients (age≥16y) documented in the TraumaRegister DGU® (TR-DGU) from January 1st 2005 to December 31st 2014 with severe chest trauma (AIS≥3) were included in this study. Demographic data, the pattern of injury, injury severity, radiographic emergency procedures, indication for intubation, duration of mechanical ventilation, emergency surgery, occurrence of complications and mortality were evaluated per year and over time. Results A total of 16,773 patients were analysed. The use of whole body computer tomography increased (p<0.001), while the incidence of plain x-rays decreased (p<0.001). Furthermore, incidence of AISThorax = 3 graded injuries increased (p<0.001) while AISThorax = 4 decreased (p<0.001). Both, rate of patients being intubated at the time of ICU admission decreased (p<0.001) and the time of mechanical ventilation decreased (p<0.001). Additionally, need for emergency surgery, lung failure, sepsis, and multi organ failure all decreased (p<0.001). However, mortality remained unchanged. Interpretation Severity of severe chest trauma and associated complications decreased while diagnostics and treatment improved over time. However, mortality remained unchanged. Our results are in line with those expected in the context of the incidence of CT diagnostics, which has increased parallel to the clinical outcome Thus, our data demonstrate a positive trend in the treatment of patients with severe chest trauma.


Deutsches Arzteblatt International | 2017

Spondylodiscitis: Diagnosis and Treatment Options

Christian Herren; Norma Jung; Miguel Pishnamaz; Marianne Breuninger; Jan Siewe; Rolf Sobottke

BACKGROUND A recent population-based study from Denmark showed that the incidence of spondylodiscitis rose from 2.2 to 5.8 per 100 000 persons per year over the period 1995-2008; the age-standardized incidence in Germany has been estimated at 30 per 250 000 per year on the basis of data from the Federal Statistical Office (2015). The early diagnosis and treatment of this condition are essential to give the patient the best chance of a good outcome, but these are often delayed because it tends to present with nonspecific manifestations, and fever is often absent. METHODS This article is based on a systematic search of Medline and the Cochrane Library for the period January 2009 to March 2017. Of the 788 articles identified, 30 publications were considered. RESULTS The goals of treatment for spondylodiscitis are to eliminate infection, restore functionality of the spine, and relieve pain. Magnetic resonance imaging (MRI) remains the gold standard for the radiological demonstration of this condition, with 92% sensitivity and 96% specificity. It also enables visualization of the spatial extent of the infection and of abscess formation (if present). The most common bacterial cause of spondylodiscitis in Europe is Staphylococcus aureus, but tuberculous spondylodiscitis is the most common type worldwide. Antibiotic therapy is a pillar of treatment for spondylodiscitis and should be a part of the treatment in all cases. Neurologic deficits, sepsis, an intraspinal empyema, the failure of conservative treatment, and spinal instability are all indications for surgical treatment. CONCLUSION The quality of life of patients who have been appropriately treated for spondylodiscitis has been found to be highly satisfactory in general, although back pain often persists. The risk of recurrence increases in the presence of accompanying illnesses such as diabetes mellitus, renal failure, or undrained epidural abscesses.


Operative Orthopadie Und Traumatologie | 2015

Perkutane dorsale Stabilisierung der Brust- und Lendenwirbelsäule mit aktiver intraoperativer Repositionsmöglichkeit

Miguel Pishnamaz; Philipp Lichte; Richard Martin Sellei; Hans Christoph Pape; Philipp Kobbe

OBJECTIVE Operative treatment of vertebral fractures is focused on stabilization of the spine and decompression of the spinal cord and nerves. In German-speaking countries, it is common to restore the sagittal profile by fracture reduction. The use of percutaneous systems has been limited due to inferior reduction possibilities compared to open systems. The improved reduction options offered by newer percutaneous systems extend their application to highly deformed fractures. INDICATIONS Unstable thoracic, lumbar and lumbosacral spine fractures; unacceptable spinal deformities. CONTRAINDICATIONS Need for open decompression or cross-bracing; relative contraindication: obesity or cachexia. SURGICAL TECHNIQUE 3 cm skin incision 1.5 cm lateral to the radiological border of the pedicle. Incision of the fascia and blunt preparation to the facet joints. Guidewire placement via fluoroscopy. Tapping and cannulated screw setting. Insertion of the longitudinal rods and reduction using special reduction tools. Rod fixation with locking caps, wound closure, dressing. POSTOPERATIVE MANAGEMENT Pain-related mobilization, physiotherapy, indication for anterior fusion to be considered. RESULTS In 2012, 80 patients (42 female, 38 male) with a mean age of 59.7 years received posterior stabilization (27 open, 53 percutaneous). Intraoperative radiation was significantly higher in the percutaneous group compared with the open group (percutaneous: 212 s; open: 146 s; p < 0.05), while the length of surgical treatment was significantly shorter (percutaneous: 107 min; open: 143 min; p < 0.05). Accuracy of screw positioning and the amount of reduction was similar in both groups. Major complications did not occur.


Global Spine Journal | 2018

Treatment of Injuries to the Subaxial Cervical Spine: Recommendations of the Spine Section of the German Society for Orthopaedics and Trauma (DGOU)

Philipp Schleicher; Philipp Kobbe; Frank Kandziora; Matti Scholz; Andreas Badke; Florian Hans Brakopp; Helmut Ekkerlein; Erol Gercek; René Hartensuer; Philipp Hartung; Jan-Sven Jarvers; Stefan Matschke; Robert Morrison; C. W. Müller; Miguel Pishnamaz; Maximilian Reinhold; Gregor Schmeiser; Klaus J. Schnake; Gregor Stein; Bernhard Ullrich; Thomas Weiss; Volker Zimmermann

Study Design: Expert consensus. Objectives: To establish treatment recommendations for subaxial cervical spine injuries based on current literature and the knowledge of the Spine Section of the German Society for Orthopaedics and Trauma. Methods: This recommendation summarizes the knowledge of the Spine Section of the German Society for Orthopaedics and Trauma. Results: Therapeutic goals are a stable, painless cervical spine and protection against secondary neurologic damage while retaining maximum possible motion and spinal profile. The AOSpine classification for subaxial cervical injuries is recommended. The Canadian C-Spine Rule is recommended to decide on the need for imaging. Computed tomography is the favoured modality. Conventional x-ray is preserved for cases lacking a “dangerous mechanism of injury.” Magnetic resonance imaging is recommended in case of unexplained neurologic deficit, prior to closed reduction and to exclude disco-ligamentous injuries. Computed tomography angiography is recommended in high-grade facet joint injuries or in the presence of vertebra-basilar symptoms. A0-, A1- and A2-injuries are treated conservatively, but have to be monitored for progressive kyphosis. A3 injuries are operated in the majority of cases. A4- and B- and C-type injuries are treated surgically. Most injuries can be treated with anterior plate stabilization and interbody support; A4 fractures need vertebral body replacement. In certain cases, additive or pure posterior instrumentation is needed. Usually, lateral mass screws suffice. A navigation system is advised for pedicle screws from C3 to C6. Conclusions: These recommendations provide a framework for the treatment of subaxial cervical spine Injuries. They give advice about diagnostic measures and the therapeutic strategy.

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