Mikako T. Oka
Tokyo Institute of Technology
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Mikako T. Oka.
Development Growth & Differentiation | 1994
Setsuko K. Satoh; Mikako T. Oka; Yukihisa Hamaguchi
In order to study the dynamic behavior of the mitotic apparatus leading to unequal cleavage, we investigated the distribution of mitotic microtubules (MTs) during maturation division of starfish oocytes. When the mitotic apparatus attached to the cell surface at metaphase, in both the first and second meiotic division, it is revealed, by immunofluorescence, that the MT distribution in the spindle, as well as in the aster, became asymmetric. MTs in the peripheral half spindle increased in number compared with those in the inner half spindle. Furthermore, these results were confirmed in the living cell by polarization microscopy; shortly after the attachment, the birefringence retardation of the peripheral half spindle became greater than that of the inner one, and the difference increased with time during anaphase. By inhibiting the attachment of the mitotic apparatus by means of centrifugation, the MT distribution maintained a symmetrical pattern through mitosis. These results suggest that the attachment of the mitotic apparatus to the cell surface induces the asymmetrical distribution of MTs not only in the aster but also in the spindle. Such a rich distribution of MTs in the peripheral half spindle appears to ensure chromosome exclusion into the polar body by anchoring them firmly to the cell surface of the animal pole.
Cytoskeleton | 1990
Mikako T. Oka; Takao Arai; Yukihisa Hamaguchi
Cytoskeleton | 1994
Mikako T. Oka; Takao Arai; Yukihisa Hamaguchi
Cell Structure and Function | 1991
Mikako T. Oka; Takao Arai; Yukihisa Hamaguchi
Cell Structure and Function | 1990
Mikako T. Oka; Takao Arai; Yukihisa Hamaguchi
生物高分子 | 2009
Yosuke Nakazawa; Makoto Takehana; Mikako T. Oka; Fukuko Shibuya; Yoh Sano
Cell Structure and Function | 1997
Mikako T. Oka; Yoko Nakajima; Masataka Obika; Takao Arai; Yukimaro Nakayama; Yukihisa Hamaguchi
日本白内障学会誌 | 2010
Masayasu Bando; Mikako T. Oka; Yosuke Nakazawa; Kenji Kawai; Hajime Obazawa; Makoto Takehana
/data/revues/07533322/unassign/S0753332210001393/ | 2010
Yosuke Nakazawa; Mikako T. Oka; Masayasu Bando; Takashi Inoue; Makoto Takehana
日本白内障学会誌 | 2009
Masayasu Bando; Takashi Inoue; Mikako T. Oka; Kenji Kawai; Hajime Obazawa; Makoto Takehana