Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where Mikio Kikuchi is active.

Publication


Featured researches published by Mikio Kikuchi.


Digestive Diseases and Sciences | 1998

Delayed gastric emptying by Helicobacter pylori lipopolysaccharide in conscious rats

Toshikatsu Okumura; Etsuro Shoji; Nobuhiko Takahashi; Hirokazu Wakebe; Kenichi Imagawa; Mikio Kikuchi; Yutaka Kohgo

The present study was carried out to investigatethe possibility that lipopolysaccharide deprived fromHelicobacter pylori may alter gastric motility. Toaddress the question, we examined the effect of H. pylori lipopolysaccharide on gastricemptying in conscious rats. Gastric emptying wasevaluated by the phenol red method. Time-course anddose-related effects of intraperitoneal administrationof H. pylori lipopolysaccharide were investigated.Intraperitoneal injection of H. pylorilipopolysaccharide significantly suppressed gastricemptying of a liquid meal in a dose-dependent manner.The inhibitory action of H. pylori lipopolysaccharide wasobserved 2, 4, 8, or 12 hr after the injection. Theseresults suggest for the first time that H. pylorilipopolysaccharide may suppress gastric emptying in along-lasting fashion. It is also suggested that H. pylorimay influence gastric function through its cell wallstructure named lipopolysaccharide.


Archive | 1994

Crude drug composition against helicobacter pylori

Yoshinori Aihara; Kenichi Imagawa; Mikio Kikuchi; Norie Mukai; Yasuo Nagata; Shuichi Sakamoto; Toshio Takizawa; Hirokazu Wakebe; 健一 今川; 浩和 分部; 典江 向井; 修一 坂本; 保夫 永田; 壽男 滝沢; 美紀 相原; 幹雄 菊地


Journal of Pharmacology and Experimental Therapeutics | 2001

Rebamipide Suppresses Formyl-methionyl-leucyl-phenylalanine (fMLP)-Induced Superoxide Production by Inhibiting fMLP-Receptor Binding in Human Neutrophils

Chifumi Nagano; Atsushi Azuma; Hironobu Ishiyama; Kazuo Sekiguchi; Kenichi Imagawa; Mikio Kikuchi


Archive | 1997

Antimicrobial, infection preventive and food product against helicobacter pylori bacteria

Takuma Imada; Mikio Kikuchi; Hiroyuki Kimura; Hiroshi Okamatsu; Takao Saito; Seiichi Shimizu; Hirokazu Wakebe; Satoko Yamahira; 拓磨 今田; 浩和 分部; 聡子 山平; 洋 岡松; 高雄 斎藤; 弘之 木村; 精一 清水; 幹雄 菊地


Biochemical and Biophysical Research Communications | 1997

Helicobacter Pylori Lipopolysaccharide Inhibits Acid Secretion in Pylorus-Ligated Conscious Rats

Chikara Ootsubo; Toshikatsu Okumura; Nobuhiko Takahashi; Hirokazu Wakebe; Kenichi Imagawa; Mikio Kikuchi; Yutaka Kohgo


Archive | 1997

DIHYDROPHENAZINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME AND DRUG FOR TUBERCLE BACILLI AND ATYPICAL ACID-FAST BACILLI

Mikio Kikuchi; Hiroshi Ishikawa; Hideaki Horimoto; Hidetsugu Tsubouchi; Takuya Shitsuta; Hirofumi Sasaki; Motohiro Itotani


Archive | 1992

Agent for inhibiting production of interleukin-8

Takahide Matsuda; Shigeru Owada; Hiroshi Muta; Miki Aihara; Hisao Takizawa; Kenichi Imagawa; Mikio Kikuchi


Hepatology | 2003

1068 Synergistic therapeutic effect of combination of interferon-alpha and interferon-gamma during the early viremic phase in a murine model of fulminant hepatic failure

Uichiro Fuchizaki; Yasunari Nakamoto; Yoshihiro Sugiyama; Kenichi Imagawa; Mikio Kikuchi; Shuichi Kaneko


Archive | 1997

Compositions against Helicobacter pylori

Mikio Kikuchi; Norie Mukai; Hiroshi Okamatsu; Takao Saito; Seiichi Shimizu; Toshio Takizawa; Hirokazu Wakebe; Satoko Yamahira; 浩和 分部; 典江 向井; 聡子 山平; 洋 岡松; 高雄 斎藤; 精一 清水; 壽男 滝沢; 幹雄 菊地


Archive | 1997

ヘリコバクター・ピロリ菌用の抗菌剤、感染予防剤および食品

Takuma Imada; Mikio Kikuchi; Hiroyuki Kimura; Hiroshi Okamatsu; Takao Saito; Seiichi Shimizu; Hirokazu Wakebe; Satoko Yamahira; 拓磨 今田; 浩和 分部; 聡子 山平; 洋 岡松; 高雄 斎藤; 弘之 木村; 精一 清水; 幹雄 菊地

Collaboration


Dive into the Mikio Kikuchi's collaboration.

Top Co-Authors

Avatar
Top Co-Authors

Avatar

Hirokazu Wakebe

Asahikawa Medical College

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Researchain Logo
Decentralizing Knowledge