Mikio Nakayama
Showa University
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Mikio Nakayama.
Antiviral Research | 1993
Mikio Nakayama; Kenji Suzuki; Masako Toda; Sachie Okubo; Yukihiko Hara; Tadakatsu Shimamura
(-)Epigallocatechin gallate (EGCg) and theaflavin digallate (TF3) (1-10 microM) inhibited the infectivity of both influenza A virus and influenza B virus in Madin-Darby canine kidney (MDCK) cells in vitro. Study by electron microscope revealed that EGCg and TF3 (1 mM) agglutinated influenza viruses as well as did antibody, and that they prevented the viruses from adsorbing to MDCK cells. EGCg and TF3 more weakly inhibited adsorption of the viruses to MDCK cells. EGCg and TF3 (1-16 microM) also inhibited haemagglutination by influenza viruses. These findings suggest that tea polyphenols bind to the haemagglutinin of influenza virus, inhibit its adsorption to MDCK cells, and thus block its infectivity.
Letters in Applied Microbiology | 1990
Mikio Nakayama; Masako Toda; Sachie Okubo; Tadakatsu Shimamura
Extracts of black tea inhibited the infectivity of influenza virus A and influenza virus B for Madin‐Darby Canine Kidney cells. Tea extract inhibited virus adsorption to the cells but did not inhibit virus replication in the cells.
The Journal of the Japanese Association for Infectious Diseases | 1996
Sadao Yabe; Mikio Nakayama; Ken-Ichiro Yamada; Tadahiko Kitano; Yoko Arai; Taisuke Horimoto; Gouta Masuda; Ayumi Mitou; Masato Tashiro
Archive | 1996
Mikio Nakayama; Tadahiko Kitano; Ayumi Mitoh; Tetsuro Ogawa; Tsuneo Hiraide
The Journal of the Japanese Association for Infectious Diseases | 1999
Yasuko Matsunaga; Sadao Yabe; Kiyosu Taniguchi; Mikio Nakayama; Ichiro Kurane
Archive | 1998
Yukihiko Hara; Mikio Nakayama
The Journal of the Japanese Association for Infectious Diseases | 1997
Masashi Iwata; Masako Toda; Mikio Nakayama; Hiroyuki Tsujiyama; Wataru Endo; Osahiko Takahashi; Yukihiko Hara; Tadakatsu Shimamura
The Journal of the Japanese Association for Infectious Diseases | 1994
Mikio Nakayama; Masako Toda; Sachie Okubo; Yukihiko Hara; Tadakatsu Shimamura
Dengue Bulletin | 2000
Ken-Ichiro Yamada; Tomohiko Takasaki; Masaru Nawa; Mikio Nakayama; Yohko T. Arai; Kinjiro Morimoto; Sadao Yabe; Ichiro Kurane
The Journal of the Japanese Association for Infectious Diseases | 1997
Masashi Iwata; Masako Toda; Mikio Nakayama; Yukihiko Hara; Tadakatsu Shimamura
