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Dive into the research topics where Milana Dezube is active.

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Featured researches published by Milana Dezube.


Bioorganic & Medicinal Chemistry Letters | 2001

1,4-Benzodiazepine peripheral cholecystokinin (CCK-A) receptor agonists.

Ronald G. Sherrill; Judd Berman; Lawrence Birkemo; Dallas K. Croom; Milana Dezube; Gregory N. Ervin; Mary K. Grizzle; Michael K James; Michael F. Johnson; Kennedy L. Queen; Thomas Rimele; Frank Vanmiddlesworth; Elizabeth Ellen Sugg

A series of 1,4-benzodiazepines, N-1-substituted with an N-isopropyl-N-phenylacetamide moiety, was synthesized and screened for CCK-A agonist activity. In vitro agonist activity on isolated guinea pig gallbladder along with in vivo induction of satiety following intraperitoneal administration in a rat feeding assay was demonstrated.


Journal of Medicinal Chemistry | 1998

N-(2-Benzoylphenyl)-l-tyrosine PPARγ Agonists. 3. Structure−Activity Relationship and Optimization of the N-Aryl Substituent

Jeff E. Cobb; Steven G. Blanchard; Evan G. Boswell; Kathleen K. Brown; Paul S. Charifson; Joel P. Cooper; Jon L. Collins; Milana Dezube; Brad R. Henke; Emily A. Hull-Ryde; Debra H. Lake; James M. Lenhard; William R. Oliver; Jeffery Oplinger; Mila Pentti; Derek J. Parks; Kelli D. Plunket; Wei-Qin Tong⊥


Journal of Medicinal Chemistry | 1996

Discovery of 1,5-Benzodiazepines with Peripheral Cholecystokinin (CCK-A) Receptor Agonist Activity. 1. Optimization of the Agonist "Trigger"

Christopher Joseph Aquino; Duncan R. Armour; Judd Berman; Larry S. Birkemo; Robin Arthur Ellis Carr; Dallas K. Croom; Milana Dezube; Robert W. Dougherty; Gregory N. Ervin; Mary K. Grizzle; Julie E. Head; Gavin Charles Hirst; Michael K James; Michael F. Johnson; Laurence J. Miller; Kennedy L. Queen; Thomas J. Rimele; David N. Smith; Elizabeth E. Sugg


Archive | 1992

Cyclic antitumor compounds

Michael J. Luzzi; Jeffrey M. Besterman; Michael G. Evans; M. Ross Johnson; Milana Dezube; Salvatore Profeta


Journal of Medicinal Chemistry | 1996

Discovery of 1,5-Benzodiazepines with Peripheral Cholecystokinin (CCK-A) Receptor Agonist Activity (II): Optimization of the C3 Amino Substituent

Gavin Charles Hirst; Christopher Joseph Aquino; Lawrence Birkemo; Dallas K. Croom; Milana Dezube; Robert W. Dougherty; Gregory N. Ervin; Mary K. Grizzle; Brad R. Henke; Michael K. James; Michael F. Johnson; Tanya Momtahen; Kennedy L. Queen; Ronald George Sherrill; Jerzy Ryszard Szewczyk; Timothy M. Willson; Elizabeth E. Sugg


Archive | 1999

SUBSTITUTED OXAZOLES AND THIAZOLES DERIVATIVES AS hPPAR GAMMA AND hPPAR ALPHA ACTIVATORS

Jon L. Collins; Milana Dezube; Jeffrey Alan Oplinger; Timothy Mark Willson


Archive | 1995

A method of inducing cholecystokinin agonist activity using 1,4-benzodiazepine compounds

Christopher Aquino; Milana Dezube; Ronald G. Sherrill; Elizabeth Ellen Sugg; Jerzy R. Szewczyk; Timothy M. Willson


Archive | 1992

Modulators of cholecystokinin

Elizabeth Ellen Sugg; Milana Dezube; Gavin C. Hirst


Archive | 1995

ACYL AMINO ACETAMIDE DERIVATIVES WITH AGONIST ACTIVITY FOR CCK-A RECEPTORS

Milana Dezube; Gavin Charles Hirst; Ronald George Sherrill; Elizabeth E. Sugg; Jerzy Ryszard Szewczyk; Timothy M. Willson


Journal of Medicinal Chemistry | 1995

Modification of receptor selectivity and functional activity in cholecystokinin peptoid ligands.

Milana Dezube; Elizabeth E. Sugg; Larry S. Birkemo; Dallas K. Croom; Robert W. Dougherty; Gregory N. Ervin; Mary K. Grizzle; Michael K James; Michael F. Johnson

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