Mildred Semidei-Pomales
New York Medical College
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Publication
Featured researches published by Mildred Semidei-Pomales.
British Journal of Haematology | 2012
Mark B. Geyer; Angela Ricci; Judith S. Jacobson; Robbie G. Majzner; Deirdre Duffy; Carmella van de Ven; Janet Ayello; Monica Bhatia; James Garvin; Diane George; Prakash Satwani; Lauren Harrison; Erin Morris; Mildred Semidei-Pomales; Joseph E. Schwartz; Bachir Alobeid; Lee Ann Baxter-Lowe; Mitchell S. Cairo
CD34‐selected haploidentical and unrelated donor allogeneic stem cell transplantation (AlloSCT) in paediatric recipients is associated with sustained engraftment and low risk of acute graft‐versus‐host disease (aGVHD), but limited by delayed immune reconstitution and increased risk of viral and fungal infection. The optimal dose of donor T cells to prevent graft failure and minimize risk of early opportunistic infection and post‐transplant lymphoproliferative disorder (PTLD), while avoiding severe aGVHD, remains unknown. We prospectively studied CD34‐selected 8–10/10 human leucocyte antigen (HLA)‐matched unrelated donor (MUD) peripheral blood stem cell transplantation (PBSCT) in a cohort of 19 paediatric AlloSCT recipients with malignant (n = 13) or non‐malignant (n = 6) diseases. T cells were added back to achieve total dose 1·0–2·5 × 105 CD3+/kg. GVHD pharmacoprophylaxis consisted only of tacrolimus. All patients engrafted neutrophils. Probabilities of grade II–IV aGVHD, limited chronic GVHD (cGVHD), and extensive cGVHD were 15·8%, 23·3%, and 0%, respectively. One patient developed PTLD. One‐year infection‐related mortality was 5·6%. T cell immune reconstitution was delayed. One‐year overall survival was 82·3%. Five patients with malignant disease ultimately died from progressive disease. CD34‐selected MUD PBSCT using a defined dose of T cell add‐back resulted in high rates of engraftment and low risk of grade II–IV aGVHD, early transplantation‐related mortality, and extensive cGVHD.
Biology of Blood and Marrow Transplantation | 2015
Mona Elmacken; Michael A. Pulsipher; Qiuhu Shi; Roger Giller; Theodore B. Moore; Lauren Harrison; Erin Morris; Olga Militano; Janet Ayello; Mildred Semidei-Pomales; Sandra Fabricatore; Xiaokui Zhang; Jodi Gurney; Jessica Hochberg; Lee-Ann Baxter Lowe; Mitchell S. Cairo
Biology of Blood and Marrow Transplantation | 2014
Julie-An Talano; Carolyn A. Keever-Taylor; Mark C. Walters; Shalini Shenoy; Theodore B. Moore; Susan K. Parsons; Cori Abikoff; Allen J. Dozor; Deborah M. Friedman; Ramanamoorthy Chitti; Qiuhu Shi; Brenda J. Grossman; Rona S. Weinberg; Erin Morris; Phyllis Brand; Daniel Mangan; Sandra Foley; Olga Militano; Janet Ayello; Mildred Semidei-Pomales; Lee Ann Baxter-Lowe; Mitchell S. Cairo
Reviews in Medical Microbiology | 2007
Ronit Reich-Slotky; Mildred Semidei-Pomales; Joseph E. Schwartz
Biology of Blood and Marrow Transplantation | 2017
Allyson Flower; Cori Abikoff; Suzan Minzer; Lauren Harrison; Michael A. Pulsipher; Qiuhu Shi; Roger Giller; Erin Morris; Liana Klejmont; Janet Ayello; Mildred Semidei-Pomales; Sandra Fabricatore; Xiaokui Zhang; Jodi Gurney; Carmella vandeVen; Jessica Hochberg; Lee-Ann Baxter Lowe; Mitchell S. Cairo
Biology of Blood and Marrow Transplantation | 2016
Mitchell S. Cairo; Julie-An Talano; Theodore B. Moore; Rona S. Weinberg; Carolyn A. Keever-Taylor; Brenda J. Grossman; Lee Ann Baxter-Lowe; Susan K. Parsons; Suzanne Braniecki; Erin Morris; Phyllis Brand; Sandra Fabricatore; Janet Ayello; Mildred Semidei-Pomales; Carmella van de Ven; Cori Abikoff; Shalini Shenoy
Biology of Blood and Marrow Transplantation | 2015
Michelle Nash; Lauren Harrison; Michael A. Pulsipher; Qiuhu Shi; Debra Abrams; Roger Giller; Berkley Nickerson; Erin Morris; Olga Militano; Janet Ayello; Mildred Semidei-Pomales; Sandra Fabricatore; Xiaokui Zhang; Jodi Gurney; Stacy Herb; Rajarajeswari Sivalenka; Carmella van de Ven; Nader Kim El-Mallawany; Cori Abikoff; Jessica Hochberg; Lee-Ann Baxter Lowe; Mitchell S. Cairo
Biology of Blood and Marrow Transplantation | 2015
Cori Abikoff; Julie-An Talano; Carolyn A. Keever-Taylor; Mark C. Walters; Shalini Shenoy; Theodore B. Moore; Susan K. Parsons; Allen J. Dozor; Deborah M. Friedman; Ramanamoorthy Chitti; Qiuhu Shi; Brenda J. Grossman; Rona S. Weinberg; Erin Morris; Phyllis Brand; Sandra Fabricatore; Olga Militano; Janet Ayello; Mildred Semidei-Pomales; Lee Ann Baxter-Lowe; Mitchell S. Cairo
Biology of Blood and Marrow Transplantation | 2018
Bronwyn Long; Sandra Fabricatore; Allyson Flower; Erin Morris; Harshini Mahanti; Qiuhu Shi; Carolyn A. Keever-Taylor; Rona S. Weinberg; Brenda J. Grossman; Julie-An Talano; Shalini Shenoy; Theodore B. Moore; Janet Ayello; Mildred Semidei-Pomales; Carmella van de Ven; Mitchell S. Cairo
Biology of Blood and Marrow Transplantation | 2017
Suzanne Braniecki; Julie-An Talano; Theodore B. Moore; Rona S. Weinberg; Carolyn A. Keever-Taylor; Brenda J. Grossman; Lee Ann Baxter-Lowe; Susan K. Parsons; Erin Morris; Phyllis Brand; Sandra Fabricatore; Janet Ayello; Mildred Semidei-Pomales; Carmella van de Ven; Cori Abikoff; Shalini Shenoy; Robert C. McKinstry; Mitchell S. Cairo