Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where Mildred Semidei-Pomales is active.

Publication


Featured researches published by Mildred Semidei-Pomales.


British Journal of Haematology | 2012

T cell depletion utilizing CD34+ stem cell selection and CD3+ addback from unrelated adult donors in paediatric allogeneic stem cell transplantation recipients

Mark B. Geyer; Angela Ricci; Judith S. Jacobson; Robbie G. Majzner; Deirdre Duffy; Carmella van de Ven; Janet Ayello; Monica Bhatia; James Garvin; Diane George; Prakash Satwani; Lauren Harrison; Erin Morris; Mildred Semidei-Pomales; Joseph E. Schwartz; Bachir Alobeid; Lee Ann Baxter-Lowe; Mitchell S. Cairo

CD34‐selected haploidentical and unrelated donor allogeneic stem cell transplantation (AlloSCT) in paediatric recipients is associated with sustained engraftment and low risk of acute graft‐versus‐host disease (aGVHD), but limited by delayed immune reconstitution and increased risk of viral and fungal infection. The optimal dose of donor T cells to prevent graft failure and minimize risk of early opportunistic infection and post‐transplant lymphoproliferative disorder (PTLD), while avoiding severe aGVHD, remains unknown. We prospectively studied CD34‐selected 8–10/10 human leucocyte antigen (HLA)‐matched unrelated donor (MUD) peripheral blood stem cell transplantation (PBSCT) in a cohort of 19 paediatric AlloSCT recipients with malignant (n = 13) or non‐malignant (n = 6) diseases. T cells were added back to achieve total dose 1·0–2·5 × 105 CD3+/kg. GVHD pharmacoprophylaxis consisted only of tacrolimus. All patients engrafted neutrophils. Probabilities of grade II–IV aGVHD, limited chronic GVHD (cGVHD), and extensive cGVHD were 15·8%, 23·3%, and 0%, respectively. One patient developed PTLD. One‐year infection‐related mortality was 5·6%. T cell immune reconstitution was delayed. One‐year overall survival was 82·3%. Five patients with malignant disease ultimately died from progressive disease. CD34‐selected MUD PBSCT using a defined dose of T cell add‐back resulted in high rates of engraftment and low risk of grade II–IV aGVHD, early transplantation‐related mortality, and extensive cGVHD.


Biology of Blood and Marrow Transplantation | 2015

A Pilot Trial of Unrelated Cord Blood Transplantation (UCBT) and Unmatched Human Placental Derived Stem Cells (HPDSC) in Children and Young Adults with Malignant and Non-Malignant Disease

Mona Elmacken; Michael A. Pulsipher; Qiuhu Shi; Roger Giller; Theodore B. Moore; Lauren Harrison; Erin Morris; Olga Militano; Janet Ayello; Mildred Semidei-Pomales; Sandra Fabricatore; Xiaokui Zhang; Jodi Gurney; Jessica Hochberg; Lee-Ann Baxter Lowe; Mitchell S. Cairo


Biology of Blood and Marrow Transplantation | 2014

Familial Haploidentical (FHI) T-Cell Depleted (TCD) with T-Cell Addback Stem Cell Transplantation for Patients with High-Risk Sickle Cell Disease (SCD) (IND 14359)

Julie-An Talano; Carolyn A. Keever-Taylor; Mark C. Walters; Shalini Shenoy; Theodore B. Moore; Susan K. Parsons; Cori Abikoff; Allen J. Dozor; Deborah M. Friedman; Ramanamoorthy Chitti; Qiuhu Shi; Brenda J. Grossman; Rona S. Weinberg; Erin Morris; Phyllis Brand; Daniel Mangan; Sandra Foley; Olga Militano; Janet Ayello; Mildred Semidei-Pomales; Lee Ann Baxter-Lowe; Mitchell S. Cairo


Reviews in Medical Microbiology | 2007

Microbial pathogens of hematopoietic stem cells – screening and testing for infectious diseases

Ronit Reich-Slotky; Mildred Semidei-Pomales; Joseph E. Schwartz


Biology of Blood and Marrow Transplantation | 2017

A Pilot Trial of Unrelated Donor Human Placenta-Derived Stem Cells (HPDSC) in Conjunction with Single Unrelated Cord Blood Transplantation (UCBT) in Children with Malignant and Non-Malignant Disease (IND 14949)

Allyson Flower; Cori Abikoff; Suzan Minzer; Lauren Harrison; Michael A. Pulsipher; Qiuhu Shi; Roger Giller; Erin Morris; Liana Klejmont; Janet Ayello; Mildred Semidei-Pomales; Sandra Fabricatore; Xiaokui Zhang; Jodi Gurney; Carmella vandeVen; Jessica Hochberg; Lee-Ann Baxter Lowe; Mitchell S. Cairo


Biology of Blood and Marrow Transplantation | 2016

Familial Haploidentical (FHI) Allogeneic Stem Cell Transplantation Utilizing CD34 Enrichment and T Cell Addback in Children, Adolescents & Adults with High-Risk Sickle Cell Disease. Rapid Engraftment, Low Incidence of Agvhd, and Sustained Donor Chimerism

Mitchell S. Cairo; Julie-An Talano; Theodore B. Moore; Rona S. Weinberg; Carolyn A. Keever-Taylor; Brenda J. Grossman; Lee Ann Baxter-Lowe; Susan K. Parsons; Suzanne Braniecki; Erin Morris; Phyllis Brand; Sandra Fabricatore; Janet Ayello; Mildred Semidei-Pomales; Carmella van de Ven; Cori Abikoff; Shalini Shenoy


Biology of Blood and Marrow Transplantation | 2015

A Pilot Trial of Unmatched Human Placental Derived Stem Cells (HPDSCs) in Conjunction with Unrelated Cord Blood Transplantation (UCBT) in Children and Young Adults with Malignant and Non-Malignant Disease (IND 14949)

Michelle Nash; Lauren Harrison; Michael A. Pulsipher; Qiuhu Shi; Debra Abrams; Roger Giller; Berkley Nickerson; Erin Morris; Olga Militano; Janet Ayello; Mildred Semidei-Pomales; Sandra Fabricatore; Xiaokui Zhang; Jodi Gurney; Stacy Herb; Rajarajeswari Sivalenka; Carmella van de Ven; Nader Kim El-Mallawany; Cori Abikoff; Jessica Hochberg; Lee-Ann Baxter Lowe; Mitchell S. Cairo


Biology of Blood and Marrow Transplantation | 2015

Treatment of High-Risk Sickle Cell Disease (SCD) with Familial Haploidentical (FHI) T-Cell Depleted (TCD) Stem Cell Transplantation with T-Cell Addback (IND 14359)

Cori Abikoff; Julie-An Talano; Carolyn A. Keever-Taylor; Mark C. Walters; Shalini Shenoy; Theodore B. Moore; Susan K. Parsons; Allen J. Dozor; Deborah M. Friedman; Ramanamoorthy Chitti; Qiuhu Shi; Brenda J. Grossman; Rona S. Weinberg; Erin Morris; Phyllis Brand; Sandra Fabricatore; Olga Militano; Janet Ayello; Mildred Semidei-Pomales; Lee Ann Baxter-Lowe; Mitchell S. Cairo


Biology of Blood and Marrow Transplantation | 2018

Assessment of Safety and Efficacy of PBSC Mobilization with G-CSF and CD34+ Enrichment and Pbmnc (CD3+) Addback in Familial Haploidentical (FHI) Adult Donors with Sickle Cell Disease Trait (SCDT) Prior to Allogeneic HSCT of High-Risk SCD Patients

Bronwyn Long; Sandra Fabricatore; Allyson Flower; Erin Morris; Harshini Mahanti; Qiuhu Shi; Carolyn A. Keever-Taylor; Rona S. Weinberg; Brenda J. Grossman; Julie-An Talano; Shalini Shenoy; Theodore B. Moore; Janet Ayello; Mildred Semidei-Pomales; Carmella van de Ven; Mitchell S. Cairo


Biology of Blood and Marrow Transplantation | 2017

Neurocognitive & Neurological Outcomes in Children, Adolescents & Young Adults with High-Risk SCD Who Have Undergone Familial Haploidentical (FHI) Allosct Utilizing CD34 Enrichment and T Cell Addback Following Myeloimmunoablative Conditioning (MAC)

Suzanne Braniecki; Julie-An Talano; Theodore B. Moore; Rona S. Weinberg; Carolyn A. Keever-Taylor; Brenda J. Grossman; Lee Ann Baxter-Lowe; Susan K. Parsons; Erin Morris; Phyllis Brand; Sandra Fabricatore; Janet Ayello; Mildred Semidei-Pomales; Carmella van de Ven; Cori Abikoff; Shalini Shenoy; Robert C. McKinstry; Mitchell S. Cairo

Collaboration


Dive into the Mildred Semidei-Pomales's collaboration.

Top Co-Authors

Avatar

Janet Ayello

New York Medical College

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Erin Morris

New York Medical College

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Cori Abikoff

New York Medical College

View shared research outputs
Top Co-Authors

Avatar

Qiuhu Shi

New York Medical College

View shared research outputs
Top Co-Authors

Avatar

Shalini Shenoy

St. Louis Children's Hospital

View shared research outputs
Top Co-Authors

Avatar

Brenda J. Grossman

Washington University in St. Louis

View shared research outputs
Top Co-Authors

Avatar
Researchain Logo
Decentralizing Knowledge