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Mineharu Hiiragi

Tohoku University

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Featured researches published by Mineharu Hiiragi.

Journal of The Chemical Society-perkin Transactions 1 | 1974

Studies on the syntheses of heterocyclic compounds. Part DLXXVII. Synthesis of 2,3,4,5-tetrahydro-1H-benzazepine derivatives by phenolic cyclisation

Tetsuji Kametani; Kazuo Kigasawa; Mineharu Hiiragi; Haruhide Ishimaru; Seiji Haga

Die aus 3-Benzyloxy-benzaldehyd und Cyanessigsaure in Benzol/NH4-acetat zugangliche Saure (I) wird zu dem Nitril (II) decarboxyliert, dessen Hydrierung am Raney-Ni unter Hochdruck das Amin (III) gibt.

Journal of The Chemical Society-perkin Transactions 1 | 1973

Studies on the syntheses of heterocyclic compounds. Part DII. Synthesis of 1-substituted 1,2,3,4-tetrahydrophthalazines by a pictet–spengler-type reaction of 3-hydroxybenzylhydrazine with carbonyl compounds

Tetsuji Kametani; Kazuo Kigasawa; Mineharu Hiiragi; Haruhide Ishimaru; T. Uryu; Seiji Haga

Condensations of 3-hydroxybenzylhydrazine with acetone, ethyl methyl ketone, diethyl ketone, cyclohexanone, and 1-methyl-4-piperidone in the presence of acid gave the 1,1-disubstituted 1,2,3,4-tetrahydrophthalazines (2)–(6). On the other hand, the reactions of 3-hydroxybenzoylhydrazine (7) with acetone, cyclohexanone, and benzalde-hyde gave the Schiffs bases (8)–(10).

Heterocycles | 1981

Studies on the Synthesis of Chemotherpeutics. Part XI. Synthesis and Antibacterial Activities of Phosphonopeptides

Tetsuji Kametani; Kazuo Kigasawa; Mineharu Hiiragi; Kikuo Wakisaka; Seiji Haga; Hideo Sugi; Keizo Tanigawa; Yukio Suzuki; Kazunaga Fukawa; Osamu Irino; Osamu Saita; Shigeru Yamabe

Journal of Medicinal Chemistry | 1980

Studies on the synthesis of chemotherapeutics. 10. Synthesis and antitumor activity of N-acyl- and N-(alkoxycarbonyl)-5-fluorouracil derivatives.

Tetsuji Kametani; Kazuo Kigasawa; Mineharu Hiiragi; Kikuo Wakisaka; Haga S; Nagamatsu Y; Sugi H; Kazunaga Fukawa; Osamu Irino; Yamamoto T; Nishimura N; Taguchi A; Taiji Okada; Nakayama M

Journal of Medicinal Chemistry | 1982

Studies on the synthesis of chemotherapeutics. 12. Synthesis and antitumor activity of N-phthalidyl-5-fluorouracil derivatives

Tetsuji Kametani; Kazuo Kigasawa; Mineharu Hiiragi; Kikuo Wakisaka; Kikuo Nakazato; Keiko Ichikawa; Kazunaga Fukawa; Osamu Irino; Naoyuki Nishimura; Taiji Okada

ChemInform | 1981

STUDIES ON THE SYNTHESES OF HETEROCYCLIC COMPOUNDS. 845. STUDIES ON THE SYNTHESIS OF CHEMOTHERAPEUTICS. 10. SYNTHESIS AND ANTITUMOR ACTIVITY OF N-ACYL- AND N-(ALKOXYCARBONYL)-5-FLUOROURACIL DERIVATIVES

Tetsuji Kametani; Kazuo Kigasawa; Mineharu Hiiragi; Kikuo Wakisaka; Seiji Haga; Y. Nagamatsu; Hideo Sugi; K. Fukawa; O. Irino; T. Yamamoto; N. Nishimura; A. Taguchi; T. Okada; M. Nakayama

Journal of Heterocyclic Chemistry | 1973

Studies on the syntheses of heteroeyelie compounds. Part DVI . Synthesis of oxynilidine and nitidine

Tetsuji Kametani; Kazuo Kigasawa; Mineharu Hiiragi; O. Kusama

Journal of Heterocyclic Chemistry | 1978

Studies on the syntheses of analgesics. Part 50. Synthesis of optically active 2-[4-(1-oxo-2-isoindolinyl)phenyl]propanoic acid. [Studies on the syntheses of heterocyclic compounds. Part 742]†‡

Tetsuji Kametani; Kazuo Kigasawa; Mineharu Hiiragi; Haruhide Ishimaru; Seiji Haga; Keiko Shirayama

Tetrahedron Letters | 1969

Novel debenzylation of quaternary ammonium salts with thiophenol.

Tetsuji Kametani; Kazuo Kigasawa; Mineharu Hiiragi; Nagatoshi Wagatsuma; Kikuo Wakisaka

ChemInform | 1983

STUDIES ON THE SYNTHESIS OF CHEMOTHERAPEUTICS. 12. SYNTHESIS AND ANTITUMOR ACTIVITY OF N-PHTHALIDYL-5-FLUOROURACIL DERIVATIVES

Tetsuji Kametani; Kazuo Kigasawa; Mineharu Hiiragi; Kikuo Wakisaka; K. Nakazato; K. Ichikawa; K. Fukawa; O. Irino; N. Nishimura; T. Okada

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Kazuo Kigasawa

Tohoku University

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Tetsuji Kametani

Hoshi University

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Nagatoshi Wagatsuma

Tohoku University

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Haruhide Ishimaru

Tohoku University

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Kikuo Wakisaka

Tohoku University

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O. Kusama

Tohoku University

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Hideo Sugi

Tohoku University

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Seiji Haga

Tohoku University

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T. Uryu

Tohoku University

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Keizo Tanigawa

Tohoku University

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