Mingying Yang
Tokyo University of Agriculture and Technology
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Publication
Featured researches published by Mingying Yang.
Biomaterials | 2004
Tetsuo Asakura; Chikako Tanaka; Mingying Yang; Juming Yao; Masato Kurokawa
There are a variety of silkworms and silk fibroins produced by them. Silks have many inherent suitable properties for biomaterials. In this paper, a novel silk-like hybrid protein, [DGG(A)(12)GGAASTGRGDSPAAS](5), which consists of polyalanine region of silk fibroin from a wild silkworm, Samia cynthia ricini, and cell adhesive region including Arg-Gly-Asp (RGD) sequence, derived from fibronectin, was designed and produced. The genes encoding the hybrid protein were constructed and expressed in Escherichia coli. The main conformation of the polyalanine region, that is, either alpha-helix or beta-sheet, could be easily controlled by treatment with different acidic solvents, trifluoroacetic acid or formic acid, respectively. This structural change was monitored with 13C CP/MAS NMR. Higher cell adhesive and growth activities of the hybrid protein compared with those of collagen were obtained.
Biomacromolecules | 2003
Tetsuo Asakura; Koji Nitta; Mingying Yang; Juming Yao; Yasumoto Nakazawa; David L. Kaplan
Journal of Biomedical Materials Research Part A | 2008
Mingying Yang; Chikako Tanaka; Kazuo Yamauchi; Kosuke Ohgo; Masato Kurokawa; Tetsuo Asakura
Journal of Biochemistry | 2005
Mingying Yang; Tetsuo Asakura
Tissue Engineering | 2007
Mingying Yang; Kazuo Yamauchi; Masato Kurokawa; Tetsuo Asakura
Polymer | 2009
Mingying Yang; Junji Kawamura; Zhenghua Zhu; Kazuo Yamauchi; Tetsuo Asakura
Polymer | 2007
Tetsuo Asakura; Juming Yao; Mingying Yang; Zhenghua Zhu; Haruko Hirose
Macromolecules | 2005
Tetsuo Asakura; Mingying Yang; Taiji Kawase; Yasumoto Nakazawa
Macromolecules | 2004
Mingying Yang; Juming Yao; Masashi Sonoyama; Tetsuo Asakura
Biomacromolecules | 2008
Mingying Yang; Tomoko Muto; David W. Knight; Andrew M. Collins; Tetsuo Asakura