Minoru Suda

Preparation of bromodifluoromethyl sulfide and its conversion to trifluoromethyl sulfide

Abstract Bromodifluoromethyl sulfides are prepared by the reaction of mercaptides with CF 2 BrX (x=Br,Cl). And treatment of bromodifluoromethyl sulfides with various inorganic fluorides produced trifluoromethyl sulfides.

Preparation and reactivity of an α-(difluoromethylene)-γ-lactone

Abstract 3-(Difluoromethylene)-4,4-dimethyloxolan-2-one, prepared by difluoronethylenation of 4,4-dimethyloxolan-2,3-dione, exhibits marked reactivity toward nucleophilic reagents.

Short-step syntheses of (±)-bazzanene and (±)trichodiene

Abstract Sesquiterpene hydrocarbons, bazzanene and trichodiene, were synthesized in three steps from a substituted allyl formate 3 .

Radical addition reactions on 1,1-difluoro-1-olefins

Abstract Radical addition reactions on 1,1-difluoro-1-olefins produced adducts having attacking radical species on the terminal carbon.

Dichloromethylenation of esters and lactones by triphenylphosphine-carbon tetrachloride reagent

Abstract Reaction of triphenylphosphine-carbon tetrachloride reagent with esters and lactones produced 1-substituted 2,2-dichlorovinyl ethers. Hydrolysis of these ethers in acidic conditions afforded the dichloromethyl ketones.

Reactions of 1,1-difluoro-1-olefins with electrophilic reagents

Abstract 1,1-Difluoro-1-olefins react smoothly with electrophilic reagents such as bromine and acid chloride-Lewis acid at room temperature producing the addition products.

Reaction of 1,1-difluorocyclopropanes with organolithium compounds

Abstract Substituted 1,1-difluorocyclopropanes react with organolithium reagents to provide either cyclopropenes or mono-substituted acetylenes depending upon the substitution patterns.