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Dive into the research topics where Mitsuhiko Fujiwara is active.

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Featured researches published by Mitsuhiko Fujiwara.


Agricultural and biological chemistry | 1982

Fermentation, Isolation and Characterization of Isonitrile Antibiotics

Akiko Fujiwara; Toru Okuda; Setsuko Masuda; Yoshihiko Shiomi; Chikara Miyamoto; Yuzuru Sekine; Masaaki Tazoe; Mitsuhiko Fujiwara

A number of soil isolates belonging to the genus Trichoderma were found to produce isonitrins A, B, C and D and isonitrinic acids E and F, a new class of antibiotics characterized by the presence of isonitrile groups. Taxonomy of the producing organisms, fermentation, isolation and physicochemical and biological properties of isonitrins and isonitrinic acids are reported. Isonitrin A showedthe highest in vitro antimicrobial activities against gram-positive and negative bacteria and fungi.


Fermentation Products#R##N#Proceedings of the Sixth International Fermentation Symposium Held in London, Canada, July 20–25, 1980 | 1981

MICROBIOLOGICAL HYDROXYLATION OF PATCHOULOL

Akiko Fujiwara; Masaaki Tazoe; Yoshihiko Shiomi; Mitsuhiko Fujiwara

ABSTRACT Screening for a specific hydroxylator of patchoulol at C-10 position was conducted among fungal strains. KEYWORDS Patchoulol; microbial transformation; microbiological hydroxylation; Penicillium rubrum; Paecilomyces carneus.


Agricultural and biological chemistry | 1982

Correlation between Species of Trichoderma and Production Patterns of Isonitrile Antibiotics

Toru Okuda; Akiko Fujiwara; Mitsuhiko Fujiwara


The Journal of Antibiotics | 1982

New anthracycline antibiotics, auramycins and sulfurmycins. I. Isolation and characterization of auramycins A and B, and sulfurmycins A and B.

Akiko Fujiwara; Tatsuo Hoshino; Masaaki Tazoe; Mitsuhiko Fujiwara


Archive | 1980

Process for the manufacture of hydroxylated steroids

Mitsuhiko Fujiwara; Akiko Fujiwara; Chikara Miyamoto


Agricultural and biological chemistry | 1978

Ornithine Decarboxylase Inhibitors of Microbial Origin A Possible Approach for Screening of Antitumor Agents

Akiko Fujiwara; Yoshihiko Shiomi; Ken Suzuki; Mitsuhiko Fujiwara


Archive | 1980

MICROBIOLOGICAL METHOD FOR THE PREPARATION OF 7-ALPHA-HYDROXYLATED STEROIDS

Mitsuhiko Fujiwara; Akiko Fujiwara; Chikara Miyamoto


Archive | 1980

Antibiotic SM-173B

Akiko Fujiwara; Mitsuhiko Fujiwara; Tatsuo Hoshino; Yuzuru Sekine; Masaaki Tazoe


Archive | 1978

Process for the preparation of 7α-hydroxylated steroids

Mitsuhiko Fujiwara; Akiko Fujiwara; Chikara Miyamoto


Japanese Journal of Medical Mycology | 1977

Studies on the Mechanism of Resistance to 5-Fluorocytosine, an Antifungal Agent, in Fungi

Chikara Miyamoto; Akiko Fujiwara; Mitsuhiko Fujiwara

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