Mitsuhisa Ozawa

Central neurofibroma of the mandible —report of a case with an immunohistochemical and electron microscopical studies

Introduction Benign neurogenic tumors of the oral cavity are classified into several typings, such as, Schwannoma, neurofibroma, nerve sheath myxoma, multiple mucosal neuroma, amputation neuroma and others. Schwannoma is probably the most common among these tumors, while the neurofibroma is a rare neoplasm in the oral cavity, especially in the intraosseous region. Electron and immunohistochemical studies of this tumor are also uncommon and inconclusive. We recently encountered a case of central neurofibroma of the right mandible and examined it by light and electron microscopic studies and by immunohistochemistry. The reported cases of central neurofibroma of the jaw are also reviewed and discussed.

Radio-pathological study of osteomyelitis of the jaw bones

ConclusionFourty seven cases of osteomyelitis of the jawbones were studied radiopathologically and the following results were observed:1.The radiological signs of most of the cases revealed mainly osteolytic changes associated with various osteoscleroses. These signs were studied according to a modified Worths classification. Sequestra were found in half of the cases.2.Histopathologically, most of the cases were diagnosed as chronic suppurative osteomyelitis.3.The average age of the patients was 47 years old. Female patients were predominant in sclerosing osteomyelitis. The mandibular molar region was the area most affected.4.Interesting cases, osteomyelitis in a child, osteomyelitis in a hemodialysis patient and on a case of sclerosing osteomyelitis (Garres) were presented and discussed.