Mo Liu

N-(2-Chloro-pyrimidin-4-yl)-N,2-di-methyl-2H-indazol-6-amine.

In the title compound, C13H12ClN5, which is a derivative of the antitumor agent pazopanib {systematic name: 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzolsulfonamide}, the indazole and pyrimidine fragments form a dihedral angle of 62.63 (5)°. In the crystal, pairs of molecules related by twofold rotational symmetry are linked into dimers through π–π interactions between the indazole ring systems [centroid–centroid distance = 3.720 (2) Å]. Weak intermolecular C—H⋯N hydrogen bonds further assemble these dimers into columns propagated in [001].

2-Methyl-6-nitro-2H-indazole.

In the title compound, C8H7N3O2, the molecular skeleton is almost planar with a maximum deviation of 0.0484 (9) Å for the methyl C atom. In the crystal, weak intermolecular C—H⋯N and C—H⋯O hydrogen bonds help to establish the packing.

1,3-Dimethyl-1H-indazol-6-amine.

The molecular skeleton of the title compound, C9H11N3, is almost planar, with a maximum deviation of 0.0325 (19) Å for the amino N atom. In the crystal, N—H⋯N hydrogen bonds establish the packing.

2-(Thio­phen-2-yl)ethyl 4-methyl­benzene­sulfonate

In the title molecule, C13H14O3S2, the thiophene and benzene rings form a dihedral angle of 13.86 (13)°. In the crystal, weak intermolecular C—H⋯O hydrogen bonds link the molecules into layers parallel to the ab plane.

Methyl 5-chloro-2-nitro-benzoate.

In the title compound, C8H6ClNO4, the nitro and acetoxy groups attached to the benzene ring at neighbouring positions are twisted from its plane by 29.4 (1) and 49.7 (1)°, respectively. In the crystal, weak C—H⋯O hydrogen bonds link molecules into layers parallel to (101). The crystal packing exhibits short intermolecular C⋯O distances of 2.925 (3) Å.

4,4′-(Cyclo­hexane-1,1-di­yl)diphenol methanol solvate

The title compound, crystallized as a methanol solvate, C18H20O2·CH3OH, is an intermediate in the synthesis of the antilipidemic agent clinofibrate. Molecules are packed together with the methanol solvent molecule via two O—H⋯O hydrogen bonds. The third O—H⋯O hydrogen bond is between neighboring 4,4′-(cyclohexane-1,1-diyl)diphenol molecules. The dihedral angle between two benzene rings planes is 81.69 (6).