Mohammed Zakariah

Optimized Gabor features for mass classification in mammography

Display Omitted Key idea is optimizing Gabor filters such that they respond stronger to features that best discriminate normal and abnormal tissues.Contribution is about a strategy based on PSO and incremental clustering for optimizing a Gabor filter bank for accurate detection.Optimized Gabor filter bank is applied on overlapping blocks of ROIs to collect moment-based features from the magnitudes of Gabor responses. Gabor filter bank has been successfully used for false positive reduction problem and the discrimination of benign and malignant masses in breast cancer detection. However, a generic Gabor filter bank is not adapted to multi-orientation and multi-scale texture micro-patterns present in the regions of interest (ROIs) of mammograms. There are two main optimization concerns: how many filters should be in a Gabor filter band and what should be their parameters. Addressing these issues, this work focuses on finding optimizing Gabor filter banks based on an incremental clustering algorithm and Particle Swarm Optimization (PSO). We employ an SVM with Gaussian kernel as a fitness function for PSO. The effect of optimized Gabor filter bank was evaluated on 1024 ROIs extracted from a Digital Database for Screening Mammography (DDSM) using four performance measures (i.e., accuracy, area under ROC curve, sensitivity and specificity) for the above mentioned mass classification problems. The results show that the proposed method enhances the performance and reduces the computational cost. Moreover, the Wilcoxon signed rank test over the significance level of 0.05 reveals that the performance difference between the optimized Gabor filter bank and non-optimized Gabor filter bank is statistically significant.

Computational prediction of Mycoplasma hominis proteins targeting in nucleus of host cell and their implication in prostate cancer etiology.

Cancer has long been assumed to be a genetic disease. However, recent evidence supports the enigmatic connection of bacterial infection with the growth and development of various types of cancers. The cause and mechanism of the growth and development of prostate cancer due to Mycoplasma hominis remain unclear. Prostate cancer cells are infected and colonized by enteroinvasive M. hominis, which controls several factors that can affect prostate cancer growth in susceptible persons. We investigated M. hominis proteins targeting the nucleus of host cells and their implications in prostate cancer etiology. Many vital processes are controlled in the nucleus, where the proteins targeting M. hominis may have various potential implications. A total of 29/563 M. hominis proteins were predicted to target the nucleus of host cells. These include numerous proteins with the capability to alter normal growth activities. In conclusion, our results emphasize that various proteins of M. hominis targeted the nucleus of host cells and were involved in prostate cancer etiology through different mechanisms and strategies.

Design and deployment challenges in immersive and wearable technologies

ABSTRACT The current century has brought an unimaginable growth in information and communications technology (ICT) and needs of enormous computing. The advancements in computer hardware and software particularly helped fuel the requirements of human beings, and revolutionized the smart products as an outcome. The advent of wearable devices from their development till successful materialisation has only taken less than a quarter of a century. The huge benefits of these smart wearable technologies cannot be fully enjoyed until and unless the reliability of a complete system is ensured. The reliability can be increased by the consistent advancements in hardware and software in parallel. User expectations actually are the challenges that keep the advancements alive while improving at an unmatchable pace. The future of wearable and other smart devices depends on whether they can provide a timely solution that is reliable, richer in resources, smaller in size, and cheaper in price. This paper addresses the threats and opportunities in the development and the acceptance of immersive and wearable technologies. The hardware and software challenges for the purpose of development are discussed to demonstrate the bottlenecks of the current technologies and the limitations that impose those bottlenecks. For the purpose of adoption, social and commercial challenges related to innovation and acceptability are discussed. The paper proposes guidelines that are expected to be applicable in several considerable applications of wearable technologies, for example, social networks, healthcare, and banking.

QoS-adaptive service configuration framework for cloud-assisted video surveillance systems

Quality of service (QoS)-adaptive service configuration is crucial for seamless access to video services in cloud-assisted video surveillance systems. To maintain seamless access to video on a user’s preferred device, suitable video transcoding services are needed. It is a challenging task to choose and configure these services for various devices to ensure QoS-adaptive user experiences. To configure these services for the desired user devices, a suitable configuration algorithm is needed. Therefore, this paper describes a QoS-adaptive service configuration approach to choose the optimal configuration for the preferred user devices in varied contexts so that the user can access the services ubiquitously. We implemented a cloud-assisted video surveillance prototype to show how the proposed method can handle ubiquitous access to target video for possible QoS-adaptive and video processing requirements in terms of bandwidth, delay, and frame rates. The results show that the proposed configuration method outperforms the other comparable approaches.

Prediction of mycoplasma hominis proteins targeting in mitochondria and cytoplasm of host cells and their implication in prostate cancer etiology.

Although the idea of bacteria causing different types of cancer has exploded about century ago, the potential mechanisms of carcinogenesis is still not well established. Many reports showed the involvement of M. hominis in the development of prostate cancer, however, mechanistic approach for growth and development of prostate cancer has been poorly understood. In the current study, we predicted M. hominis proteins targeting in the mitochondria and cytoplasm of host cells and their implication in prostate cancer. A total of 77 and 320 proteins from M. hominis proteome were predicted to target in the mitochondria and cytoplasm of host cells respectively. In particular, various targeted proteins may interfere with normal growth behaviour of host cells, thereby altering the decision of programmed cell death. Furthermore, we investigated possible mechanisms of the mitochondrial and cytoplasmic targeted proteins of M. hominis in etiology of prostate cancer by screening the whole proteome.

A novel audio forensic data-set for digital multimedia forensics

Abstract Today, digital multimedia (audio, video, images) is a common evidential source in litigation and criminal justice proceedings, and, not surprisingly, multimedia forensics is an active research area. One particular challenge faced by multimedia forensic researchers is the lack of a comprehensive and publicly available data-set for evaluating existing and new algorithms. This paper presents a digital audio forensic data-set, designed to facilitate evaluation of audio forensic algorithms (e.g. microphone identification, acoustic environment identification and splice detection). This paper also briefly describes the data-collection settings, microphones, speakers, languages and notations used. Existing tamper-detection techniques rely on artefacts due to recording devices, codec and/or the acoustic environment in the audio in question. Experimental results show that the selected approaches achieved promising results.

Visual Tracking in Unknown Environments Using Fuzzy Logic and Dead Reckoning

This paper addresses the problem of making a non-holonomic wheeled mobile robot (WMR) move to a target object using computer vision and obstacle-avoidance techniques. If a priori information about the obstacles is available, pre-planning the desired path can be a good candidate method. However, in so many cases, obstacles are dynamic. Therefore, our first challenge is to make the WMR move to a desired target while autonomously avoiding any obstacle along its path. The second challenge deals with visual-tracking loss; that is, when the target is lost from the camera scope, the robot should use Dead Reckoning (DR) to get back on its path towards the target. The Visual Tracking (VT) algorithm then takes the relay to reach the final destination, compensating for any errors due to DR by calculating the distance to the target when it is within the scope of the camera. The proposed system also uses two fuzzy-logic controllers; the first controller avoids objects while the second manages the path to the target. Different complex scenarios have been implemented, showing the validity of our multi-controller model.

Enhancement of mobile robot localization using extended Kalman filter

In this article, we introduce a localization system to reduce the accumulation of errors existing in the dead-reckoning method of mobile robot localization. Dead-reckoning depends on the information that comes from the encoders. Many factors, such as wheel slippage, surface roughness, and mechanical tolerances, affect the accuracy of dead-reckoning. Therefore, an accumulation of errors exists in the dead-reckoning method. In this article, we propose a new localization system to enhance the localization operation of the mobile robots. The proposed localization system uses the extended Kalman filter combined with infrared sensors in order to solve the problems of dead-reckoning. The proposed system executes the extended Kalman filter cycle, using the walls in the working environment as references (landmarks), to correct errors in the robot’s position (positional uncertainty). The accuracy and robustness of the proposed method are evaluated in the experiment results’ section.

Digital multimedia audio forensics: past, present and future

Digital audio forensics is used for a variety of applications ranging from authenticating audio files to link an audio recording to the acquisition device (e.g., microphone), and also linking to the acoustic environment in which the audio recording was made, and identifying traces of coding or transcoding. This survey paper provides an overview of the current state-of-the-art (SOA) in digital audio forensics and highlights some open research problems and future challenges in this active area of research. The paper categorizes the audio file analysis into container and content-based analysis in order to detect the authenticity of the file. Existing SOA, in audio forensics, is discussed based on both container and content-based analysis. The importance of this research topic has encouraged many researchers to contribute in this area; yet, further scopes are available to help researchers and readers expand the body of knowledge. The ultimate goal of this paper is to introduce all information on audio forensics and encourage researchers to solve the unanswered questions. Our survey paper would contribute to this critical research area, which has addressed many serious cases in the past, and help solve many more cases in the future by using advanced techniques with more accurate results.

To Decipher the Mycoplasma hominis Proteins Targeting into the Endoplasmic Reticulum and Their Implications in Prostate Cancer Etiology Using Next-Generation Sequencing Data

Cancer was initially considered a genetic disease. However, recent studies have revealed the connection between bacterial infections and growth of different types of cancer. The enteroinvasive strain of Mycoplasma hominis alters the normal behavior of host cells that may result in the growth of prostate cancer. The role of M. hominis in the growth and development of prostate cancer still remains unclear. The infection may regulate several factors that influence prostate cancer growth in susceptible individuals. The aim of this study was to predict M. hominis proteins targeted into the endoplasmic reticulum (ER) of the host cell, and their potential role in the induction of prostate cancer. From the whole proteome of M. hominis, 19 proteins were predicted to be targeted into the ER of host cells. The results of our study predict that several proteins of M. hominis may be targeted to the host cell ER, and possibly alter the normal pattern of protein folding. These predicted proteins can modify the normal function of the host cell. Thus, the intercellular infection of M. hominis in host cells may serve as a potential factor in prostate cancer etiology.