Moon-Hyang Park

Idiopathic Palmar Fasciitis with Polyarthritis Syndrome

A 31-yr-old Korean woman was presented with 4-month history of bilateral hand swelling and stiffness. On clinical examination, she had a painful synovitis of both hands, wrists, knees and ankles. The radiologic and histological examinations confirmed it with palmar fasciitis and polyarthritis syndrome (PFPAS). PFPAS is an uncommon disorder characterized by progressive flexion contractures of both hands, inflammatory fasciitiis, fibrosis, and a generalized inflammatory arthritis. Although most reported cases of PFPAS have been associated with various malignancies, our patient have not been associated with malignancy during 24 months follow up period from her first symptom onset. Her symptoms were improved with moderate dose of corticosteroid and she is currently taking prednisone 5 mg daily without any evidence for internal malignancy. We present here in a young Korean patient with idiopathic PFPAS who was successfully treated with administration of corticosteroid.

Aneurysmal Dilatation of Ascending Aorta and Aortic Insufficiency in Juvenile Spondyloarthropathy

Aortic insufficiency is a well-recognized complication of adult spondyloarthropathy but rare in juveniles, and no report is associated with aneurysmal dilatation at any age. We describe rapidly progressive aortic insufficiency with aneurysmal dilatation of ascending aorta in a 15-year-old boy with juvenile spondyloarthropathy, necessitating a Bentall operation.

Muscular amyloidoma presenting as inguinal masses in multiple myeloma

We report a case with protruding inguinal masses for 6 months, in whom muscular amyloidoma was not suspected before muscle biopsy. On pelvic magnetic resonance imaging (MRI), round masses showing peripheral rim enhancement with gadolinium were observed in iliopsoas and iliacus muscles of both inguinal areas. The same lesions were also observed in gluteus muscles. The biopsy showed Congo red positive materials in a dense fibrous background. Serum and urine electrophoresis showed Bence Jones protein, lambda type. In bone marrow section, myeloma cells were found. Peripheral blood stem cell transplantation (PBSCT) following four cycles of VAD (vincristine, adriamycin, dexamethasone) chemotherapy was performed and the result was satisfactory. Amyloidoma lesions decreased in size and number on the following MRI.

Secondary Amyloidosis Associated with Multiple Sclerosis

Background Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. Secondary amyloidosis can occur as a complication of chronic systemic inflammatory and infectious diseases. Until now there has been no report of secondary amyloidosis associated with MS. We report herein a case of renal biopsy-proven secondary amyloidosis in a patient with MS. Case Report A 41-year-old woman with MS was hospitalized due to aggravated quadriparesis and edema in both lower extremities. Laboratory findings showed nephrotic-range proteinuria and hypoalbuminemia. A percutaneous renal biopsy procedure was performed, the results of which revealed secondary amyloid-A-type amyloidosis associated with MS. Conclusions This is the first report of secondary amyloidosis associated with MS.

Fine needle aspiration cytology of alveolar soft part sarcoma of the cheek

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Effects of aristolochic acid I and/or hypokalemia on tubular damage in C57BL/6 rat with aristolochic acid nephropathy

Background/Aims This study was designed to investigate the roles of aristolochic acid I (AA-I) and hypokalemia in acute aristolochic acid nephropathy (AAN). Methods After an adaptation period (1 week), a total of 40 C57BL/6 mice (male, 8 weeks old) were divided into four groups: I (control group), II (low potassium [K] diet), III (normal K diet with administration of AA-I [10 mg/kg weight]), and IV (low K diet with AA-I). After collecting 24 hours of urine at 2 weeks, the mice were sacrificed, and their blood and kidneys were obtained to perform immunochemical staining and/or Western blot analysis. Results Proteinuria, glycosuria, and increased fractional excretion of sodium and K were prominent in groups III and IV (p < 0.05). Diffuse swelling and poor staining of collecting duct epithelial cells were evident in the medullas of group II. Typical lesions of toxic acute tubular injury were prominent in the cortices of groups III and IV. Α-Smooth muscle actin (α-SMA) was higher in the cortices of the mice in groups III and IV versus group II (p < 0.05), and higher in the medullas of group IV than groups I and III (p < 0.05). E-cadherin was higher in the cortices of groups III and IV compared to group I (p < 0.05). The F4/80 value was higher in the cortices and medullas of groups II, III, and IV compared to group I (p < 0.05), particularly in the case of group II. Conclusions AA-I can induce acquired Fanconi syndrome in the acute stage of AAN. Macrophages appear to play a key role in the pathogenesis of AAN and hypokalemic nephropathy. It remains uncertain whether hypokalemia plays any role in AAN and hypokalemia.

A study on design of magnetization yoke of ferrite spoke-type permanent magnet synchronous motor considering demagnetization

The study proposed a design of magnetization yoke of ferrite spoke-type permanent magnet synchronous motor. A high magnetic field intensity(H) is required for the magnetization of permanent magnet, meaning that the analysis of nonlinear finite elements methods is needed considering saturation of core. The permanent magnet is placed deeply to the shaft especially in spoke-type motor. The high H, however, may cause demagnetization of surrounding permanent magnets, making the design of spoke-type magnetization yoke to be difficult. This study proposes the interpole winding to reduce the demagnetization of surrounding permanent magnets and analysis of power supply source considering magnetizer, derives the structure of optimized magnetization yoke to meeting the criteria of magnetization and demagnetization by analyzing field, and finally verifies the results of this study by manufacturing and testing.

A study on the inductance calculation of flux concentrating permanent magnet motor through non-linear magnetic equivalent circuit

In order to design a permanent magnet synchronous motor, the inductance must be computed. In this paper, the flux concentrating permanent magnet synchronous motor (FCPMSM) is introduced. It is not easy to calculate the inductance because of the complex structure of the rotor. Because the rib and bridge consists of an iron core, they have a non-linear characteristic. In order to obtain the effective value of inductance, non-linear characteristics must be considered in magnetic equivalent circuit (MEC). In this paper, in order to calculate the inductance of FCPMSM, the relative permeance of rotor was analyzed. And then d-q axis magnetic equivalent circuit including non-linear magnetic reluctance was made up using the flux line. Finally, we verified the validity of the proposed inductance calculation method by comparing the results between the finite element method and the proposed method.