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Featured researches published by Moses Mwangi.


Diabetes Care | 2012

Prevalence of Metabolic Syndrome Among an Urban Population in Kenya

Lydia Kaduka; Yeri Kombe; Eucharia Unoma Kenya; Elizabeth Nafula Kuria; John K. Bore; Zipporah N. Bukania; Moses Mwangi

OBJECTIVE Developing countries are undergoing an epidemiologic transition accompanied by increasing burden of cardiovascular disease (CVD) linked to urbanization and lifestyle modifications. Metabolic syndrome is a cluster of CVD risk factors whose extent in Kenya remains unknown. The aim of this study was to determine the prevalence of metabolic syndrome and factors associated with its occurrence among an urban population in Kenya. RESEARCH DESIGN AND METHODS This was a household cross-sectional survey comprising 539 adults (aged ≥18 years) living in Nairobi, drawn from 30 clusters across five socioeconomic classes. Measurements included waist circumference, HDL cholesterol, triacylglycerides (TAGs), fasting glucose, and blood pressure. RESULTS The prevalence of metabolic syndrome was 34.6% and was higher in women than in men (40.2 vs. 29%; P < 0.001). The most frequently observed features were raised blood pressure, a higher waist circumference, and low HDL cholesterol (men: 96.2, 80.8, and 80%; women: 89.8, 97.2, and 96.3%, respectively), whereas raised fasting glucose and TAGs were observed less frequently (men: 26.9 and 63.3%; women: 26.9 and 30.6%, respectively). The main factors associated with the presence of metabolic syndrome were increasing age, socioeconomic status, and education. CONCLUSIONS Metabolic syndrome is prevalent in this urban population, especially among women, but the incidence of individual factors suggests that poor glycemic control is not the major contributor. Longitudinal studies are required to establish true causes of metabolic syndrome in Kenya. The Kenyan government needs to create awareness, develop prevention strategies, and strengthen the health care system to accommodate screening and management of CVDs.


BMC Health Services Research | 2013

Existence and functionality of emergency obstetric care services at district level in Kenya: theoretical coverage versus reality

Elizabeth Echoka; Yeri Kombe; Dominique Dubourg; Anselimo Makokha; Bjørg Evjen-Olsen; Moses Mwangi; Jens Byskov; Øystein Evjen Olsen; Richard Mutisya

BackgroundThe knowledge on emergency obstetric care (EmOC) is limited in Kenya, where only partial data from sub-national studies exist. The EmOC process indicators have also not been integrated into routine health management information system to monitor progress in safe motherhood interventions both at national and lower levels of the health system. In a country with a high maternal mortality burden, the implication is that decision makers are unaware of the extent of need for life-saving care and, therefore, where to intervene. The objective of the study was to assess the actual existence and functionality of EmOC services at district level.MethodsThis was a facility-based cross-sectional study. Data were collected from 40 health facilities offering delivery services in Malindi District, Kenya. Data presented are part of the “Response to accountable priority setting for trust in health systems” (REACT) study, in which EmOC was one of the service areas selected to assess fairness and legitimacy of priority setting in health care. The main outcome measures in this study were the number of facilities providing EmOC, their geographical distribution, and caesarean section rates in relation to World Health Organization (WHO) recommendations.ResultsAmong the 40 facilities assessed, 29 were government owned, seven were private and four were voluntary organisations. The ratio of EmOC facilities to population size was met (6.2/500,000), compared to the recommended 5/500,000. However, using the strict WHO definition, none of the facilities met the EmOC requirements, since assisted delivery, by vacuum or forceps was not provided in any facility. Rural–urban inequities in geographical distribution of facilities were observed. The facilities were not providing sufficient life-saving care as measured by caesarean section rates, which were below recommended levels (3.7% in 2008 and 4.5% in 2009). The rates were lower in the rural than in urban areas (2.1% vs. 6.8%; p < 0.001 ) in 2008 and (2.7% vs. 7.7%; p < 0.001) in 2009.ConclusionsThe gaps in existence and functionality of EmOC services revealed in this study may point to the health system conditions contributing to lack of improvements in maternal survival in Kenya. As such, the findings bear considerable implications for policy and local priority setting.


Journal of Nutrition and Metabolism | 2014

Food Insecurity and Not Dietary Diversity Is a Predictor of Nutrition Status in Children within Semiarid Agro-Ecological Zones in Eastern Kenya

Zipporah N. Bukania; Moses Mwangi; Robert M. Karanja; Richard Mutisya; Yeri Kombe; Lydia Kaduka; Timothy Johns

Machakos and Makueni counties in Kenya are associated with historical land degradation, climate change, and food insecurity. Both counties lie in lower midland (LM) lower humidity to semiarid (LM4), and semiarid (LM5) agroecological zones (AEZ). We assessed food security, dietary diversity, and nutritional status of children and women. Materials and Methods. A total of 277 woman-child pairs aged 15–46 years and 6–36 months respectively, were recruited from farmer households. Food security and dietary diversity were assessed using standard tools. Weight and height, or length in children, were used for computation of nutritional status. Findings. No significant difference (P > 0.05) was observed in food security and dietary diversity score (DDS) between LM4 and LM5. Stunting, wasting, and underweight levels among children in LM4 and LM5 were comparable as were BMI scores among women. However, significant associations (P = 0.023) were found between severe food insecurity and nutritional status of children but not of their caregivers. Stunting was significantly higher in older children (>2 years) and among children whose caregivers were older. Conclusion. Differences in AEZ may not affect dietary diversity and nutritional status of farmer households. Consequently use of DDS may lead to underestimation of food insecurity in semiarid settings.


International Journal for Equity in Health | 2014

Using the unmet obstetric needs indicator to map inequities in life-saving obstetric interventions at the local health care system in Kenya.

Elizabeth Echoka; Dominique Dubourg; Anselimo Makokha; Yeri Kombe; Øystein Evjen Olsen; Moses Mwangi; Bjørg Evjen-Olsen; Jens Byskov

BackgroundDeveloping countries with high maternal mortality need to invest in indicators that not only provide information about how many women are dying, but also where, and what can be done to prevent these deaths. The unmet Obstetric Needs (UONs) concept provides this information. This concept was applied at district level in Kenya to assess how many women had UONs and where the women with unmet needs were located.MethodsA facility based retrospective study was conducted in 2010 in Malindi District, Kenya. Data on pregnant women who underwent a major obstetric intervention (MOI) or died in facilities that provide comprehensive Emergency Obstetric Care (EmOC) services in 2008 and 2009 were collected. The difference between the number of women who experienced life threatening obstetric complications and those who received care was quantified. The main outcome measures in the study were the magnitude of UONs and their geographical distribution.Results566 women in 2008 and 724 in 2009 underwent MOI. Of these, 185 (32.7%) in 2008 and 204 (28.1%) in 2009 were for Absolute Maternal Indications (AMI). The most common MOI was caesarean section (90%), commonly indicated by Cephalopelvic Disproportion (CPD)–narrow pelvis (27.6% in 2008; 26.1% in 2009). Based on a reference rate of 1.4%, the overall MOI for AMI rate was 1.25% in 2008 and 1.3% in 2009. In absolute terms, 22 (11%) women in 2008 and 12 (6%) in 2009, who required a life saving intervention failed to get it. Deficits in terms of unmet needs were identified in rural areas only while urban areas had rates higher than the reference rate (0.8% vs. 2.2% in 2008; 0.8% vs. 2.1% in 2009).ConclusionsThe findings, if used as a proxy to maternal mortality, suggest that rural women face higher risks of dying during pregnancy and childbirth. This indicates the need to improve priority setting towards ensuring equity in access to life saving interventions for pregnant women in underserved areas.


The Pan African medical journal | 2016

Factors associated with adequate weekly reporting for disease surveillance data among health facilities in Nairobi County, Kenya, 2013

Athman Juma Mwatondo; Zipporah Ng’ang’a; Caroline Wanjiku Maina; Lindah Makayotto; Moses Mwangi; Ian Njeru; Wences Arvelo

Introduction Kenya adopted the Integrated Disease Surveillance and Response (IDSR) strategy in 1998 to strengthen disease surveillance and epidemic response. However, the goal of weekly surveillance reporting among health facilities has not been achieved. We conducted a cross-sectional study to determine the prevalence of adequate reporting and factors associated with IDSR reporting among health facilities in one Kenyan County. Methods Health facilities (public and private) were enrolled using stratified random sampling from 348 facilities prioritized for routine surveillance reporting. Adequately-reporting facilities were defined as those which submitted >10 weekly reports during a twelve-week period and a poor reporting facilities were those which submitted <10 weekly reports. Multivariate logistic regression with backward selection was used to identify risk factors associated with adequate reporting. Results From September 2 through November 30, 2013, we enrolled 175 health facilities; 130(74%) were private and 45(26%) were public. Of the 175 health facilities, 77 (44%) facilities classified as adequate reporting and 98 (56%) were reporting poorly. Multivariate analysis identified three factors to be independently associated with weekly adequate reporting: having weekly reporting forms at visit (AOR19, 95% CI: 6-65], having posters showing IDSR functions (AOR8, 95% CI: 2-12) and having a designated surveillance focal person (AOR7, 95% CI: 2-20). Conclusion The majority of health facilities in Nairobi County were reporting poorly to IDSR and we recommend that the Ministry of Health provide all health facilities in Nairobi County with weekly reporting tools and offer specific trainings on IDSR which will help designate a focal surveillance person.


The Pan African medical journal | 2017

A study to determine the prevalence and factors associated with hypertension among employees working at a call centre Nairobi Kenya.

Mwagi Joseph Onyango; Iyeri Kombe; Daniel Sagwe Nyamongo; Moses Mwangi

Introduction Hypertension often referred to as Non Communicable Diseases (NCDs). Causes of hypertension are classified into modifiable and non-modifiable factors. The objective of the study was to determine the prevalence and other associated factors leading to the onset of hypertension among employees working at the call center. Methods This was a descriptive cross sectional study design. Data collection was done in two parts; part one comprised of clinical health assessments; weight and height to aid determine Body Mass Index and blood pressure measurement. Part two was by self-administered questionnaires to participants to aid identify behavioral risk factors and further elicit lifestyle practices. Data was collected from a sample population of 370 respondents. Descriptive statistical analysis was applied in univariate analysis. Further analysis included bivariate and multiple regression analysis; Odds Ratio with 95% confidence interval was used to determine the strength of association. Results The proportion of hypertension was significantly higher among overweight respondents (32.7%) (OR= 11.55; 95% CI= 4.44-30.07; P < 0.001) and obese respondents (60.2%) (OR= 36.02; 95% CI= 13.43-96.60; P < 0.001) compared to those respondents who were within normal range of weight (4.0%). Nine (9) factors that were associated with hypertension at bivariate analysis (P < 0.05) were all subjected to a multiple regression analysis or reduced model where four factors remained in the final analysis. Respondents who were classified as overweight had 10.6 times likelihood developing hypertension compared to those respondents with normal weight (AOR= 10.61; 95%CI= 3.98-28.32; P < 0.001). Likewise, obese respondents were 43.6 fold more likely to develop hypertension compared to those respondents within normal range of weight [OR=43.68; 95%CI=15.24-125.16; P<0.001]. Respondents not trying to reduce fat in their diet were highly predisposed having hypertension at (AOR=2.44; 95% CI=1.20-4.96; P= 0.014) than respondents who always tried to reduce fat in their diet. Respondents who sometimes engage on more physical exercises were 2.2 times likely to develop hypertension (AOR=2.22; 95%CI= 1.20-4.10; P= 0.011) compared to those who always engaged in more physical exercises. Respondents with parenting issues were about twice as likely to have hypertension (AOR= 2.15; 95% CI: 1.23-3.74; P= 0.007) than parents who did not have parenting issues. Conclusion This study depicts rising cases of hypertension and an alarming rate of pre-hypertension among the working population. This vary based on the age, obesity, parental responsibility, unhealthy diet and lack of or reduced physical activity. These call for strategic interventions and greater emphasis on health promotion programs at the workplace alongside staff empowerment towards health seeking behaviors.


BMC Public Health | 2011

Delivery Practices and Associated Factors among Mothers Seeking Child Welfare Services in Selected Health Facilities in Nyandarua South District, Kenya

Carol Wanjira; Moses Mwangi; Evans Mathenge; Gabriel Mbugua; Zipporah Ng'ang'a


Parasites & Vectors | 2014

Field-derived Schistosoma mansoni and Biomphalaria pfeifferi in Kenya: a compatible association characterized by lack of strong local adaptation, and presence of some snails able to persistently produce cercariae for over a year

Martin W. Mutuku; Celestine K Dweni; Moses Mwangi; Joseph M. Kinuthia; Ibrahim N. Mwangi; Geoffrey M. Maina; Lelo E. Agola; Si-Ming Zhang; Rosebella O. Maranga; Eric S. Loker; Gerald M. Mkoji


Africa Health Agenda International Journal | 2018

Double burden of malnutrition among cancer outpatients in Nairobi, Kenya: challenges and opportunities for action

Yvonne Opanga; Lydia Kaduka; Erastus Muniu; Zipporah N. Bukania; Richard Mutisya; Ann Korir; Veronica Thuita; Catherine Nyongesa; Moses Mwangi; Charles Mbakaya


Journal of Epidemiology and Preventive Medicine | 2017

Inadequate and Excessive Urinary Iodine Concentration in School Age Girls and Women in Makueni, Eastern Kenya

Zipporah N. Bukania; Judith Kimiywe; Timothy Johns; Moses Mwangi; Lydia Kaduka; Frits van der

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Lydia Kaduka

Kenya Medical Research Institute

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Yeri Kombe

Kenya Medical Research Institute

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Zipporah N. Bukania

Kenya Medical Research Institute

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Richard Mutisya

Kenya Medical Research Institute

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Anselimo Makokha

Jomo Kenyatta University of Agriculture and Technology

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Ann Korir

Kenya Medical Research Institute

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Elizabeth Echoka

Kenya Medical Research Institute

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Erastus Muniu

Kenya Medical Research Institute

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Veronica Thuita

Kenyatta National Hospital

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