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Featured researches published by Motoaki Ishigaki.


The American Journal of Chinese Medicine | 1994

Inhibitory effects of sho-seiryu-to on acetylcholine-induced responses in nasal gland acinar cells.

Katsuhisa Ikeda; Dazheng Wu; Motoaki Ishigaki; Hiroshi Sunose; Tomonori Takasaka

Sho-seiryu-to, a traditional Japanese herbal medicine, has been used extensively in the treatment of allergic rhinitis. The effects of Sho-seiryu-to on electrical responses induced by acetylcholine in dissociated nasal gland acinar cells were investigated using patch-clamp and microfluorimetric imaging techniques. The application of Sho-seiryu-to inhibited both K+ and Cl- currents augmented by acetylcholine. The elevation of intracellular Ca2+ and Na+ concentrations induced by acetylcholine was also inhibited by Sho-seriyu-to. These findings suggest that Sho-seiryu-to attenuated the secretion of water and electrolytes from the nasal glands through an anti-cholinergic effect.


American Journal of Physiology-lung Cellular and Molecular Physiology | 1995

Intracellular Ca2+ responses induced by acetylcholine in the submucosal nasal gland acinar cells in guinea pigs

Katsuhisa Ikeda; Motoaki Ishigaki; Dazheng Wu; Hiroshi Sunose; Masaaki Suzuki; K. Ishitani; Tomonori Takasaka


Biochemical and Biophysical Research Communications | 1994

Ionic Currents Evoked by Acetylcholine in Isolated Acinar Cells of the Guinea Pig Nasal Gland

Dazheng Wu; Hiroshi Sunose; Katsuhisa Ikeda; Motoaki Ishigaki; Tomonori Takasaka


Journal of Cellular Physiology | 1995

Na+ transport processes in isolated guinea pig nasal gland acinar cells

Katsuhisa Ikeda; Motoaki Ishigaki; Dazheng Wu; Hiroshi Sunose; Tomonori Takasaka


Acta Physiologica Scandinavica | 1994

Isolation of acini from nasal glands of the guinea-pig

Hiroshi Sunose; W. Zhang; Motoaki Ishigaki; Yukio Katori; Masaaki Suzuki; Katsuhisa Ikeda; Tomonori Takasaka; Yoshitaka Saito; Akinori Nishiyama


Nippon Jibiinkoka Gakkai Kaiho | 1988

The influence of meteorological factors upon the pollen counts of Cryptomeria japonica

Naoki Inamura; Yoshihiro Shibahara; Motoaki Ishigaki; Tomonori Takasaka; Yuko Sato


Nippon Jibiinkoka Gakkai Kaiho | 1995

INTRACELLULAR Ca2+ RESPONSE INDUCED BY ACETYLCHOLINE IN THE SUBMUCOSAL NASAL GLAND ACINAR CELLS OF GUINEA PIGS

Motoaki Ishigaki; Katsuhisa Ikeda; Hiroshi Sunose; Masaaki Suzuki; Tomonori Takasaka


Practica oto-rhino-laryngologica | 1993

Dissociation of the Submucosal Nasal Gland of the Nasal Septum in Guinea Pigs.

Motoaki Ishigaki; Katsuhisa Ikeda; Hiroshi Sunose; Yukio Katori; Masaaki Suzuki; Tomonori Takasaka


Nippon Jibiinkoka Gakkai Kaiho | 1993

THREE PATIENTS WITH GAS GANGRENE OF THE HEAD AND NECK

Kiyoyuki Ohi; Naoki Inamura; Mamoru Suzuki; Naohiro Suzuki; Motoaki Ishigaki; Tomonori Takasaka


THE JOURNAL OF JAPAN SOCIETY FOR LASER SURGERY AND MEDICINE | 1992

Laser Application to endoscopic sinus surgery

Katsuhisa Ikeda; Motoaki Ishigaki; Kazuto Matsuura; Tomonori Takasaka

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