Motohiro Takeda
Takeda Pharmaceutical Company
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Publication
Featured researches published by Motohiro Takeda.
Organic and Medicinal Chemistry Letters | 2011
Noriyasu Kato; Mitsuru Oka; Takayo Murase; Masahiro Yoshida; Masao Sakairi; Mirensha Yakufu; Satoko Yamashita; Yoshika Yasuda; Aya Yoshikawa; Yuji Hayashi; Masahiro Shirai; Yukie Mizuno; Mitsuaki Takeuchi; Mitsuhiro Makino; Motohiro Takeda; Takuji Kakigami
Focused structure-activity relationships of isoindoline class DPP-IV inhibitors have led to the discovery of 4b as a highly selective, potent inhibitor of DPP-IV. In vivo studies in Wistar/ST rats showed that 4b was converted into the strongly active metabolite 4l in high yield, resulting in good in vivo efficacy for antihyperglycemic activity.
Archive | 2004
Takuji Kakigami; Mitsuru Oka; Noriyasu Katoh; Masahiro Yoshida; Masahiro Shirai; Toru Murase; Masao Sakairi; Takayo Murase; Mitsuaki Takeuchi; Yuji Hayashi; Motohiro Takeda; Mitsuhiro Makino
Archive | 2001
Kazumasa Miyawaki; Yuichiro Yamada; Nobuhiro Ban; Yutaka Seino; Yoshiharu Tubamoto; Motohiro Takeda; Hiroyuki Hashimoto; Tokuyuki Yamashita; Takahito Jomori
Archive | 2003
Yuji Hayashi; Mitsuhiro Makino; Toshiyuki Kouzaki; Motohiro Takeda; Takahito Jomori
Archive | 2004
Motohiro Takeda; Noriaki Ohuchi; Yoshiyuki Kawazoe; Atsuo Kasuya
Archive | 2004
Takuji Kakigami; Mitsuru Oka; Noriyasu Katoh; Masahiro Yoshida; Masahiro Shirai; Toru Murase; Masao Sakairi; Mitsuaki Takeuchi; Yuji Hayashi; Motohiro Takeda; Mitsuhiro Makino
Archive | 2009
Kohsuke Gonda; 幸祐 権田; Hideo Higuchi; 秀男 樋口; Noriaki Ohuchi; 憲明 大内; Motohiro Takeda; 元博 武田
Archive | 2003
Yuji Hayashi; Mitsuhiro Makino; Toshiyuki Kouzaki; Motohiro Takeda; Takahito Jomori
Archive | 2001
Kazumasa Miyawaki; Yuichiro Yamada; Nobuhiro Ban; Yutaka Seino; Yoshiharu Tubamoto; Motohiro Takeda; Hiroyuki Hashimoto; Tokuyuki Yamashita; Takahito Jomori
Archive | 2012
Hiroyuki Hashimoto; Toshihiko Kumazawa; Motohiro Takeda; Takahito Jomori; Chihiro Hibi; Kuniharu Mizuno
