Muhammed Bilal Cegin

Effectivity of one session charcoal hemoperfusion treatment in severe carbamazepine poisoning.

A carbamazepine intoxication with suicide attempt is a relatively common clinical problem that presenting with coma, respiratory depression, arrhythmia, hemodynamic instability and even death. We report a case of severe carbamazepine poisoning that was successfully treated with one session charcoal hemoperfusion. On admission, the patient was comatose and required ventilator support. Hemoperfusion with coated activated charcoal successfully decreased the serum carbamazepine concentration from 45 µg mL−1 to 21 µg mL−1 within 2 h, with subsequent clinical improvement.

Management of anesthesia in biotinidase deficiency.

of BD include neurological (seizures, ataxia, hypotonia, developmental delay, hearing and vision loss), neuromuscular (muscle weakness, spinal cord diseases), dermatological (seborrheic dermatitis, alopecia, skin rash), and metabolic abnormalities (chronic lactic acidosis, organic aciduria). It is also associated with respiratory problems (apnea, dyspnea, tachypnea) and immune deficiency findings. [1-4] Treatment with biotin results in a rapid clinical and biochemical improvement. However, if untreated, the disease can lead to coma and death. A 2-year-old boy weighing 12 kg was scheduled for a probing procedure due to lacrimal duct obstruction. BD was diagnosed and treated with biotin when the patient was 4-month-old. Patient has no episode of seizure over the last year and has used biotin 20 mg/day without antiepileptic drug. Physical examination was normal except the crusted lesions on skin and scalp of recent chicken pox infections. Laboratory findings were normal except anemia due to

Successful use of sugammadex for caesarean section in a patient with myasthenia gravis

Myasthenia gravis is an autoimmune disorder that is characterized by muscle weakness that fluctuates, worsening with exertion, and improving with rest. Diagnosis of myasthenia gravis is made following clinical and physical examination and is confirmed by serum immunoassays to measure autoantibody levels. Myasthenia gravis especially when associated with pregnancy is a high-risk disease, and its course is unpredictable. We described the second report about use of sugammadex after rocuronium for a caesarean delivery with myasthenia gravis, but, unlike our case that formerly was diagnosed with myasthenia gravis, the patient was extubated on postoperative successfully and we did not encounter any respiratory problems.

Femoral-Sciatic Nerve Block in a Patient with Von Willebrand's Disease: A Case Report

Von Willebrand hastalığı, vWf eksikliği veya fonksiyon bozukluklarına bağlı görülen otozomal geçişli bir kalıtsal kanama diyatezidir (1). vWh en sık görülen kalıtsal kanama diyatezlerinden biridir. Toplum taraması ile elde edilen insidans rakamları %1 dolayındadır (2). vWh, tipik olarak hafif veya orta şiddette deri mukoza kanamalarıyla karakterizedir. Sık görülen semptomlar, deride kolay ekimoz oluşması, burun kanaması, diş eti kanaması, menoraji, postpartum kanamalar, yüzeyel kesilerden sonra uzun süren kanamalar ve GIS kanamalarıdır. Kanamanın şiddeti vWf’nin düzeyine ve fonksiyon bozukluğu olup olmadığına göre farklılık gösterir (3). Bu sunuda koagulopatili bir olguda peroperatif koagulasyon faktörleri verilerek, USG eşliğinde başarılı bir periferik blok uygulaması sunulmuştur. Olgu Sunumu