Muhammet Gokhan Turtay

Protective effects of hesperidin in experimental testicular ischemia/reperfusion injury in rats

Introduction In this study, we aimed to determine the protective effects of hesperidin, a citrus flavonoid, in a model of testicular ischemia/reperfusion injury in rats. Material and methods Forty-two pubertal male Wistar-Albino rats were divided into six groups: group 1 – control; group 2 – 50 mg/kg hesperidin (low dose hesperidin) used without torsion (LH group); group 3 – 100 mg/kg hesperidin without torsion (HH group); group 4 – torsion/detorsion group (T/D); group 5 – T/D + 50 mg/kg hesperidin treatment group (T/D + LH); and group 6 – T/D + 100 mg/kg hesperidin treatment group (T/D + HH). Hesperidin was given to the treatment groups 30 min before detorsion. After the fourth hour of reperfusion, orchiectomy was performed on the rats under anesthesia. The tissue samples were examined histologically and biochemically. Results In the T/D group testicular malondialdehyde (MDA) levels were increased significantly (p < 0.001) whereas superoxide dismutase (SOD), catalase (CAT) and glutathione (GSH) levels were decreased compared to the control and other groups. However, hesperidin caused the effect of T/D to become closer to normal biochemical values. In addition, the histological examinations showed that T/D caused damage in the testis but hesperidin reduced this effect. The effects of hesperidin were found to be dose dependent. Thus, applying high doses would generate greater therapeutic effects. Conclusions In a rat testicular T/D model we observed biochemical and histological damage due to ischemia. However, high and low dose applications of hesperidin were shown to have protective effects against this damage. Therefore, the aforementioned citrus flavonoid may provide positive results in cases of testicular torsion.

Unexpected lumbar abscess due to scarification wet cupping: A case report

OBJECTIVE This case presents a rare cause of lumbar abscess. METHODS A 51-year-old male patient was admitted to the emergency department with a complaint of lumbar pain. Spinal magnetic resonance imaging revealed a lumbar abscess. RESULTS The abscess was treated with drainage of the abscess and antibiotic. CONCLUSION Scarification wet cupping therapy should be taken into consideration as a rare cause of lumbar abscesses in patients who present with skin findings indicative of scarification. Scarification wet cupping therapy practitioners must pay attention to hygienic measures.

Evaluation of the intensive care management of patients with spinal cord trauma

Spine traumas and the resulting spinal cord injuries are among the most important health problems with their physical and psychosocial impacts due to significant mortality and morbidity. Our objective in this study was to evaluate the issues that should be taken into consideration during the intensive care treatment management of patients monitored for spinal cord trauma. Patient files were examined for obtaining the demographic and clinical properties of 68 patients followed up with spine trauma diagnosis at the Intensive Care Unit during the dates of June 2011- 2016. Age, gender, cause of trauma, trauma localization, trauma injury accompanying the spine trauma, deep vein thrombosis development, infection development, ASIA (American Spinal Injury Association) score, duration of intensive care stays, and properties were examined. An evaluation was made in our study according to ASIA scoring as a result of which it was determined that there are 4 ASIA A patients (5.88%) hospitalized or discharged, 5 ASIA B patients (7.35%), 14 ASIA C patients (20.58%), 24 ASIA D patients (35.29%) and 5 ASIA score E (neurologically intact) (7.35%) patients, while mortality rate was determined as 16 patients (23.52%). It was determined as a result of the evaluation carried out with regard to post-trauma intensive care unit length of stays that the average length of stay was 21.3 days with the shortest length of stay as 1 day and the longest as 96 days. Care attributes should be familiar for this patient group that requires a multidisciplinary approach and serious rehabilitation and a sufficient level of knowledge should be reached by all those involved in the follow-up procedure.

Chilaiditi Syndrome: A Rare Cause of Shortness of Breath and Abdominal Pain

Introduction: Chilaiditi syndrome is a rare condition in which a segment of the small or large intestine is interposed in between the diaphragm and the liver. This case report presents a patient who was admitted to the Department of Emergency Medicine, Turgut Ozal Medical Center with complaints of respiratory distress and abdominal pain and then diagnosed with Chilaiditi syndrome.Case Report: An 81-year-old female patient was admitted to the emergency department with complaints of difficulty in breathing and abdominal pain. The patient’s anamnesis indicated that difficulty of breathing increased when she had abdominal pain. There was no defense or rebound, but sensitivity was observed on abdominal examination. Other system examinations were normal. Abdominal ultrasonography performed on the patient was also normal. A dynamic thorax-abdominal tomography was obtained in terms of differential diagnosis of the patient who had abdominal pain. In the dynamic thorax-abdominal tomography of the patient, loops of the colon were visualized in the vicinity of the liver anterior segment, and these images indicated with Chiliaditi syndrome.Conclusion: As a result, when the causes of shortness of breath and abdominal pain are investigated, Chiliaditi syndrome should be considered as a differential diagnosis

ST Segment Elevation Caused by Pericarditis: A Case Report

Gogus agrisi acil servise sik basvuru nedenlerinden biridir ve olumcul hastaliklarin habercisi olmasi nedeni ile onemli bir semptomdur. Basit bir kas agrisindan miyokard enfarktusune ya da daha olumcul olan aort diseksiyonuna kadar hastaliklarin habercisi olabilir. Bu acidan hastalarin degerlendirilmesinde kritik oneme sahip elektrokardiyogram (EKG) bize yol gostericidir. Ancak EKG’ye bakilarak tani konulup trombolitik tedavi baslamak yanlis tedavi olabilir. Bu yuzden hastalarin tanisinda detaya inilmeli ve tedavi plani buna gore yapilmalidir. Bu olgu sunumunda; acil servisimize gogus agrisi sikayeti ile basvuran, cekilen EKG’sinde D2, D3 ve aVF derivasyonlarinda ST segment elevasyonu ve troponin yuksekligi olan akut perikardit tanisi alan 19 yasindaki erkek hastayi sunmayi amacladik

The Evaluation of Electrocardiogram Findings in Acute Abdominal Pain Patients Admitted to the Emergency Department

The aim of this study was to determine the diagnostic value of electrocardiogram in differential diagnosis of patients with nonspecific abdominal pain. This prospective observational study was conducted in a university emergency department over 2 weeks. One hundred twenty patients with complaints of abdominal pain were admitted to the emergency department. During the study period, a total of 120 cases were evaluated. The final emergency department disposition status of the 120 patients was 1 (0.8%) died in the emergency department, 28 (23.3%) were admitted to the general ward, 27 (22.5%) were admitted to other services, and 10 (8.3%) were admitted to the cardiology service and coronary care unit. The examination indicated that 38 (31.7%) patients with abdominal pain showed cardiac pathologies on their electrocardiograms; 3 (2.5%) patients with abdominal pain admitted to cardiology service had ST elevation, and 2 (1.6%) had electrocardiogram depression on their electrocardiograms. According to the results, the authors claim that the electrocardiogram played an important role in the treatment and diagnosis of patients presenting with abdominal pain in emergency medicine. For this reason, it was thought that emergency medicine specialists should understand the basis of the perception of abdominal pain and develop a focused approach to the initial evaluation of these patients.