Murali Srinivasan

Survival rates of short (6 mm) micro-rough surface implants: a review of literature and meta-analysis.

OBJECTIVE The aim of this review was to test the hypothesis that 6 mm micro-rough short Straumann(®) implants provide predictable survival rates and verify that most failures occurring are early failures. MATERIALS AND METHODS A PubMed and hand search was performed to identify studies involving micro-rough 6-mm-short implants published between January 1987 and August 2011. Studies were included that (i) involve Straumann(®) 6 mm implants placed in the human jaws, (ii) provide data on the survival rate, (iii) mention the time of failure, and (iv) report a minimum follow-up period of 12 months following placement. A meta-analysis was performed on the extracted data. RESULTS From a total of 842 publications that were screened, 12 methodologically sound articles qualified to be included for the statistical evaluation based on our inclusion criteria. A total of 690 Straumann(®) 6-mm-short implants were evaluated in the reviewed studies (Total: placed-690, failed-25; maxilla: placed-266, failed-14; mandible: placed-364, failed-5; follow-up period: 1-8 years). A meta-analysis was performed on the calculated early cumulative survival rates (CSR%). The pooled early CSR% calculated in this meta-analysis was 93.7%, whereas the overall survival rates in the maxilla and mandible were 94.7% and 98.6% respectively. Implant failures observed were predominantly early failures (76%). CONCLUSION This meta-analysis provides robust evidence that micro-rough 6-mm-short dental implants are a predictable treatment option, providing favorable survival rates. The failures encountered with 6-mm-short implants were predominantly early and their survival in the mandible was slightly superior.

Loading protocols for implant-supported overdentures in the edentulous jaw: a systematic review and meta-analysis.

PURPOSE High survival rates have frequently been reported for immediately loaded implants. The aim of this systematic review was to compare immediately loaded with early and conventional loaded implants for overdenture treatment with regard to their 1-year survival rates. MATERIALS AND METHODS Systematic database (Medline, Embase, CENTRAL) and hand searches were performed to identify prospective studies reporting on loading protocols for two-piece implants with micro-rough surfaces and diameters > 3 mm. Studies were grouped according to loading protocol, jaw, number of implants per jaw, and splinting. Meta-analyses of comparative reports were performed based on the calculated risk difference (RD). Descriptive analyses included the remainder prospective studies. Two investigators extracted the data independently. Kappa statistics served to evaluate the inter-investigator agreement. RESULTS Of the 3,142 identified articles, 58 were included for data extraction. They comprised 11 studies comparing loading protocols as well as a further 47 prospective reports. Comparative studies were only available for mandibular overdentures. The meta-analysis revealed a statistical tendency to support conventional over immediate loading (RD: -0.03, 95% confidence interval: -0.06, 0.00). The descriptive analysis of studies with lower evidence demonstrated partially contradictory findings. There, reported survival rates for immediately loaded implants lay between 81.6% and 100%, but depended on the number of implants placed. Most investigators preferred verifying an initial high insertion torque (≥ 35 Ncm) or ISQ value (≥ 60) before considering an implant for an immediate or early loading protocol. CONCLUSIONS Although all three loading protocols provide high survival rates, early and conventional loading protocols are still better documented than immediate loading and seem to result in fewer implant failures during the first year. Only a few prospective case series are available to document immediate loading of implants supporting an overdenture in the edentulous maxilla.

Effects of in vitro cyclic dislodging on retentive force and removal torque of three overdenture attachment systems.

BACKGROUND Mandibular two-implant-retained overdentures were suggested as first choice of treatment for edentulous mandibles. However, wear of the attachments may reduce their retention and compromise long-term clinical success. AIM The aim of this in vitro study was to compare the change in the retentive force and removal torque of three attachment systems during simulation of insertion-removal cycles. MATERIALS AND METHODS Thirty custom-manufactured polyvinyl chloride blocks mimicking an implant-retained overdenture using Locator(®) -, spherical Dalbo(®) -PLUS - and SFI(®) -Bar-attachments on Straumann(®) RN Implants were fabricated. The samples were distributed equally into three groups which were subdivided into two sets of five blocks, one set with implants parallel to one another and the other with angulated implants (12°). All attachments were tightened to 35Ncm, while the fixation screws of the SFI(®) -Bar were tightened to 15Ncm. Testing was carried out with an Instron(®) universal testing machine for a total of 14,600 insertion-removal cycles in 0.9% sodium chloride solution. Retentive forces from cycles 10, 100, 1000, 5000, 10,000 and 14,600 were used for the analysis. The removal torque of the attachments was measured before and at the end of the study. Statistical analysis comprised three-way ANOVA and multiple linear regression models. RESULTS Initially, all three attachment systems demonstrated increasing retentive forces. From cycle 5000 on, Locator(®) -attachments showed lower mean retentive forces than the Dalbo(®) -PLUS and SFI(®) -Bar-groups. The Dalbo(®) -PLUS and SFI(®) -Bar-attachments showed a steady yet not significant increase during the whole observation period. Implant-angulation had no significant influence on the retention forces. The final mean removal torques were significantly reduced. No complete failure was observed. CONCLUSIONS AND CLINICAL IMPLICATIONS Within the limits of this in vitro study, it can be concluded that the investigated overdenture attachment systems are sufficiently resistant to wear. However, the Dalbo(®) -Plus- and SFI(®) -Bar- exhibit higher retentive capacities than the Locator(®) -attachment over time. The fixation screw of the SFI(®) -Bar may loosen during long-term use, but these observations might be less important if 1-year recall intervals are respected. An angulation of up to 12° between implants does not seem to have a significant effect on attachment wear.

Implant survival in 1- versus 2-implant mandibular overdentures: a systematic review and meta-analysis.

OBJECTIVE This systematic review was performed to compare the survival of 1- vs. 2-implant overdentures (IODs) in the edentulous mandible. MATERIALS AND METHODS Manual and electronic database (PubMed, EMBASE and CENTRAL) searches were performed to identify scientific articles, published in English, reporting on mandibular IODs utilizing unsplinted attachments. Studies were included if they were prospective human studies reporting on two-piece microrough surface implants with a diameter ≥3 mm. Data were extracted by two independent investigators, and an overall inter-investigator kappa score was calculated. A meta-analysis was performed on the included comparative studies. RESULTS The search shortlisted 30 prospective studies for data extraction and statistical analysis. The included studies comprised of only two randomized controlled trials (RCTs) comparing 1- vs. 2-IODs, and a further 28 prospective studies. The kappa score calculated was between 0.86 and 1 for the various parameters. One RCT favored 1-IODs (RD: 0.08, 95% CI: 0.01, 0.14) while the other favored 2-IODs (RD:-0.04, 95% CI: -0.27, 0.19). However, the overall random effects model did not reveal a significant risk difference (RD) for implant failure between the two interventions (I(2) = 36.6%, P = 0.209; RD: 0.05, 95% CI: -0.07, 0.18). CONCLUSIONS The results of this meta-analysis conclude that the postloading implant survival of 1-IODs is not significantly different from 2-IODs. However, the existing scientific evidence in the literature in terms of prospective comparative studies is scarce. Hence, before recommending the 1-IOD as a treatment modality, long-term observations are needed and a larger range of functional, prosthodontic, and patient-centered outcome measures should be considered.

High‐fluoride toothpaste: a multicenter randomized controlled trial in adults

Objective The aim of this single – blind, multicenter, parallel, randomized controlled trial was to evaluate the effectiveness of the application of a high-fluoride toothpaste on root caries in adults. Methods Adult patients (n = 130, ♂ = 74, ♀ = 56; mean age ± SD: 56.9 ± 12.9) from three participating centers, diagnosed with root caries, were randomly allocated into two groups: Test (n = 64, ♂ = 37, ♀ = 27; lesions = 144; mean age: 59.0 ± 12.1; intervention: high-fluoride toothpaste with 5000 ppm F), and Control (n = 66, ♂ = 37, ♀ = 29; lesions = 160; mean age: 54.8 ± 13.5; intervention: regular-fluoride toothpaste with 1350 ppm F) groups. Clinical examinations and surface hardness scoring of the carious lesions were performed for each subject at specified time intervals (T0 – at baseline before intervention, T1 – at 3 months and T2 – at 6 months after intervention). Mean surface hardness scores (HS) were calculated for each patient. Statistical analyses comprised of two-way analysis of variance and post hoc comparisons using the Bonferroni–Dunn correction. Results At T0, there was no statistical difference between the two groups with regard to gender (P = 0.0682, unpaired t-test), or age (P = 0.9786, chi-squared test), and for the overall HS (Test group: HS = 3.4 ± 0.61; Control group: HS = 3.4 ± 0.66; P = 0.8757, unpaired t-test). The anova revealed significantly better HS for the test group than for the control groups (T1: Test group: HS = 2.9 ± 0.67; Control group: HS = 3.1 ± 0.75; T2: Test group: HS = 2.4 ± 0.81; Control group: HS = 2.8 ± 0.79; P < 0.0001). However, the interaction term time-point*group was not significant. Conclusions The application of a high-fluoride containing dentifrice (5000 ppm F) in adults, twice daily, significantly improves the surface hardness of otherwise untreated root caries lesions when compared with the use of regular fluoride containing (1350 ppm F) toothpastes.

Influence of implant angulation and cyclic dislodging on the retentive force of two different overdenture attachments - an in vitro study

OBJECTIVE This in vitro study evaluated the influence of implant angulations on the retentive behavior of two overdenture attachments during cyclic dislodging. METHODS Models simulating a two-implant overdenture situation were fabricated. They were divided into five groups based on their simulated implant angulations (Groups: 1 = 0°; 2 = 20°; 3 = 30°; 4 = 40°; and 5 = 60°; n = 90). Each group was further divided into two subgroups based on its attachment system (control attachment: LOCATOR(®) ; test attachment: SFI-Anchor(®) ) except for group 5 which had no LOCATOR(®) group. All models underwent 10,000 insertion-removal cycles in a wet environment. Mean retentive forces were recorded. ANOVA and linear regression models were used for statistical analyses, and the level of significance was at P < 0.05. RESULTS The ANOVA model revealed an effect of dislodging cycles for both attachments (P = 0.0070). The linear regression model with repeated measures revealed a significant effect of angulation within the LOCATOR(®) groups (0° vs. 20°: P < 0.0001; 0° vs. 30°: P < 0.0001; 0° vs. 40°: P < 0.0001), but was insignificant within the SFI-Anchor(®) groups (0° vs. 20°: P = 0.544; 0° vs. 30°: P = 0.134; 0° vs. 40°: P = 0.254; 0° vs. 60°: P = 0.979). It further revealed a significant increase in the retentive force between the LOCATOR(®) and the SFI-Anchor(®) (20°: P = 0.041; 30°: P < 0.0001; 40°: P < 0.0001), although there was no significant difference between the attachments at 0° (P = 0.623). CONCLUSIONS This study confirms that the retentive behavior of SFI-Anchor(®) is not influenced by implant axial inclination even at angulations of up to 60°. The SFI-Anchor(®) may therefore be particularly indicated for clinical situations with marked implant axial discrepancies.

Dental Appearance and Personality Trait Judgment of Elderly Persons

PURPOSE The study aimed to investigate the personality judgments made by observers of elderly individuals with different dental appearances. MATERIALS AND METHODS A random sample of 120 elderly (57 men, 63 women; third age: n = 51, mean age: 68.6 ± 5.0 years; fourth age: n = 69, mean age: 85.8 ± 3.0 years) and 120 young (54 men, 66 women; mean age: 24.9 ± 3.5 years) subjects were included. Decayed, natural, and ideal dental appearances were simulated on photographs of an elderly man and woman. Participants were asked to judge the personality traits of two randomly selected photographs. Univariate and multivariate analyses were performed. RESULTS Both groups judged the photographs similarly by attributing a higher social class to the individuals with an ideal dental appearance (elderly group: P = .0295 for the male subject, P = .0420 for the female subject; young group: P = .0003 for the male subject, P = .0042 for the female subject). This difference was less obvious when only the third-age participants were analyzed; they attributed a higher social class to the photograph of the man with a natural dental appearance than to the man with decayed and ideal appearances (P = .0322 and P = .0092, respectively) and lower intellectual capacities to the woman with a decayed appearance (P = .0351). The fourth-age subgroup made no such distinction. CONCLUSIONS Personality judgments made by young and elderly persons are influenced by dental appearance. However, in the very old subgroup, no such influence could be verified. Dental esthetics should not be neglected in dental care for elderly patients.

CAD/CAM milled complete removable dental prostheses: An in vitro evaluation of biocompatibility, mechanical properties, and surface roughness

This study compared the biocompatibility, mechanical properties, and surface roughness of a pre-polymerized polymethyl methacrylate (PMMA) resin for CAD/CAM complete removable dental prostheses (CRDPs) and a traditional heat-polymerized PMMA resin. Two groups of resin substrates [Control (RC): conventional PMMA; Test (RA): CAD/CAM PMMA] were fabricated. Human primary osteoblasts and mouse embryonic-fibroblasts were cultured for biocompatibility assays. Mechanical properties and surface roughness were compared. ANOVA revealed no difference between the resin groups in the biocompatibility assays. RA demonstrated a higher elastic modulus (p=0.002), youngs modulus (p=0.002), plastic energy (p=0.002), ultimate strength (p=0.0004), yield point (p=0.016), strain at yield point (p=0.037), and toughness (p<0.0001); while RC displayed a higher elastic energy (p<0.0001). Laser profilometry concluded a rougher surface profile (p<0.0001) for RA. This study concluded that the tested CAD/CAM resin was equally biocompatible and presented with improved mechanical properties than the traditional heat-polymerized PMMA resin used in the fabrication of CRDPs.

Impact of lingual plates on the interocclusal free way space: a pilot study

Palatal augmentation prostheses are commonly used in the treatment for dysphagia. By lowering the palatal contours, the tongue contact is increased and thus the bolus propulsion facilitated. However, the unfavourable weight of such appliances may be avoided when using lingual plates. Hence, the aim of this study is to investigate the effect of two different types of lingual plates on the vertical dimension in rest position. Eleven healthy dentate subjects with an average age of 35.5 years (26-60 years) volunteered in this pilot study. The vertical overbites were measured on plaster models. Two different designs of the experimental lingual plates were tested in this pilot study (P-type & D-type). The inter-occlusal freeway space was measured using the electromagnetic K7 jaw-tracking system (Myotronics, U.S.A.), while the subjects were seated in an upright position. They were asked to close from rest position into maximum intercuspation for about 2 s. Recordings were performed without the plates and subsequently with each of the two plate designs in situ. All recordings were performed three times and the second closing movement of each recording was used for the analysis. After averaging the repetitions without experimental lingual plates, with P-type and D-type plates, the differences were analysed using a Kruskall-Wallis test. The results showed no significantly increased freeway space while using both types of lingual plates. Hence, it can be concluded that any altered tongue pressure during swallowing with lingual plates is not related to an increase in vertical dimension.

Comparison of user satisfaction and image quality of fixed and mobile camera systems for 3-dimensional image capture of edentulous patients: A pilot clinical study

Statement of problem. An evaluation of user satisfaction and image quality of a novel handheld purpose‐built mobile camera system for 3‐dimensional (3D) facial acquisition is lacking. Purpose. The purpose of this pilot clinical study was to assess and compare the effectiveness between a handheld mobile camera system designed for facial acquisition and a fixed static camera arrangement by comparing the time effectiveness and the operator and participant preference for the 2 techniques of image capture. Material and methods. Completely edentulous participants (n=12: women=7, men=5; mean age: 74.6 years) were included in this pilot study. Images were captured with and without the prostheses in situ while maintaining “serious” and “full‐smile” facial expressions. Images were captured using a mobile and a static system. The working times for the participant installation and image captures were recorded. Operator and participant perceptions of the entire experience were recorded by using visual analog scale questionnaires. Nonparametric tests were used for statistical analyses (&agr;=.05). Results. The installation time was significantly shorter for the mobile system (static=24 ±13 seconds; mobile=10 ±10 seconds), but the differences in the image capture times were not statistically significant (static: 29 ±5 seconds; mobile: 40 ±18 seconds). Operator preference was in favor of the mobile system with regard to working time (P=.002), difficulty in using (installation: P=.002; handling: P=.045), and camera weight (P=.002); however, they preferred the static arrangement for image quality (P=.003) and comfort (P=.013). The participants rated the entire photographic experience favorably, and 10 of 12 participants preferred the static camera over the mobile one. Conclusions. Despite the complexity of the installation, the static system was evaluated better for image quality; the mobile system was easier in installation and handling. The operators preferred the mobile system, and the participants preferred the static system.