Murat Demiroglu

Protective effects of Nigella sativa on gamma radiation-induced jejunal mucosal damage in rats.

INTRODUCTION The aim of this study was to compare the efficacy of Nigella sativa in protection of jejunal mucosa against harmful effects of gamma radiation. METHODS Radiotherapy group received abdominal gamma radiation of 15Gy in addition to physiological saline. Radiotherapy+Nigella sativa treatment group received abdominal gamma radiation of 15Gy in addition to Nigella sativa treatment in the amount of 400mg/kg. Radiotherapy and treatment groups were sacrificed 3 days after the exposure to irradiation. Then, jejunum samples were harvested for biochemical and histological assessment of mucosal injury. RESULTS Nigella sativa treatment was found to significantly lower elevated tissue malondialdehyde (MDA) levels and, to raise reduced glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) activity in intestinal tissues samples. Single dose 15Gy gamma-irradiation was noted to result in a marked jejunal mucosal injury. Three days after exposure to irradiation, the villi and Lieberkühn crypts were observed as denuded, and villous height diminished. Concomitantly with inflammatory cell invasion, capillary congestion and ulceration were observed in the atrophic mucosa. Nigella sativa treatment significantly attenuated the radiation induced morphological changes in the irradiated rat jejunal mucosa. CONCLUSION Nigella sativa has protective effects against radiation-induced damage, suggesting that clinical transfer is feasible.

A case of schwannoma of the common peroneal nerve in the knee

Schwannomas are benign neurogenic tumors of peripheral nerves that originate from neural sheath. The aim of this case report is to bring to mind the schwannoma in the patient with knee pain. A 39-year-old woman presented with a complaint of knee pain of three months history. After surgical intervention, the patient’s complaints completely disappeared in the post-operative period. This should come to mind in the differential diagnosis of knee pain.

Deep peroneal nerve palsy due to osteochondroma arising from fibular head and proximal lateral tibia

Highlights • Osteochondroma are the most common benign tumors.• Disease affecting knee joint in 94% of all cases.• Clinicians should be aware of the possible tumoral lesions in drop foot etiology.

Comparison between two anatomic landmarks using ultrasonography in spinal anesthesia: a randomized controlled trial.

Abstract Background and objective: Tuffier’s line is the most used anatomic landmark in clinical practice. We aimed to compare the accuracy of Tuffier’s line with a landmark that joins the two lowest points of the tenth rib on the flanks with the help of ultrasound. Methods: A prospective, randomized, controlled, double-blinded trial was performed with 200 patients aged between 18 and 50. Patients taller than 180 cm or shorter than 150 cm, or with body mass index >30 kg/m2 were excluded. The first anesthesiologist examined Group T according to Tuffier’s line and Group R according to the tenth rib line and marked L4–5. Only one anesthesiologist evaluated the marked level with ultrasound for accuracy of the anesthesiologist’s examination. Results: There was no difference between groups for demographic and surgical data (p > 0.05). However, we observed a significant difference between the two techniques for success rate (60% in group T vs. 74% in group R) at estimation of correct level (p < 0.05). There was no correlation between success of estimation and patients’ demographic data. Conclusion: We conclude that the tenth rib line is better than Tuffier’s line for accuracy with palpation. However, it must be confirmed by further studies including more than one examiner for palpation and also include different patient populations.

Lung Metastasis Mimicking Fingertip Infection

Metastasis fingers (acral metastasis) are finding a poor prognosis. Past medical history should be questioned and metastasis from primary tumor should be kept in mind in patients with pain, swelling, and hyperemia in fingers. Successful surgical treatment on acral metastasis does not extend the life expectancy; however, it reduces the patients pain during his terminal period, saves the functions of the limb, and increases life comfort.

A rare case of a medullary, multifocal lesion in the distal radius

In multifocal findings, the possibility of multifocal osteoid osteomas should be considered and this case helps us to be attentive for the unusual radiographical presentation of osteoid osteoma.

A rarely seen lipoma variant: Osteochondrolipoma: Case report

received: 28.11.2015 Accepted: 11.01.2016 1Department of Pathology, Istanbul Medeniyet University, Göztepe Training and Research Hospital 2Department of Orthopedics, Istanbul Medeniyet University, Göztepe Training and Research Hospital Yazışma adresi: Ayşe Bahar Ceyran, Department of Pathology, Istanbul Medeniyet University, Göztepe Training and Research Hospital, İstanbul e-mail: baharceyran@gmail.com GİrİŞ

Preiser's disease in a five-fingered hand.

Abstract Preiser’s disease, also known as idiopathic avascular necrosis of the scaphoid, and five-fingered hand are rare hand conditions. In this report, we present a case of a 25 year old female patient who had avascular necrosis of the scaphoid and five-fingered hand.